Deck 25: Drug Therapy During Pregnancy and Lactation

Question 1

Which of the following is NOT a sign and symptom of preeclampsia?

A) weight gain
B) high blood pressure
C) protein in the urine
D) blood in the urine

Answer 1

blood in the urine

Question 2

During pregnancy, special attention should be given to which of the following problems first?

A) urogenital
B) cardiovascular
C) respiratory
D) skin

Answer 2

cardiovascular

Question 3

Seizures in a pregnant woman can cause:

A) pernicious anemia
B) megaloblastic anemia
C) fetal ictus
D) fetal hypoxia

Answer 3

fetal hypoxia

Question 4

High doses of fluoxetine (Prozac ) in pregnant women have been shown to cause what in newborn babies?

A) decreased birth weight
B) increased birth weight
C) increased blood pressure
D) decreased blood pressure

Question 5

Which of the following treatments is preferred for gestational diabetes?

A) oral hypoglycemic drugs
B) insulin
C) only dieting
D) only exercise and dieting

Question 6

Pernicious vomiting during pregnancy is known as:

A) preeclampsia
B) eclampsia
C) hyperglycemia
D) hyperemesis gravidarum

Question 7

Which of the following are the drugs of choice for preeclampsia?

A) magnesium and diazepam
B) magnesium and hydralazine
C) magnesium and antihistamine
D) folic acid and hydrochlorothiazide

Question 8

Which of the following agents can produce a hostile environment capable of causing a spontaneous abortion?

A) alcohol
B) aspirin
C) nicotine
D) coffee

Question 9

During pregnancy, the heart rate increases about:

A) 5 to 10 beats per minute
B) 10 to 15 beats per minute
C) 30 to 40 beats per minute
D) 40 to 45 beats per minute

Question 10

Plasma lipid levels increase throughout pregnancy, altering drug:

A) distribution
B) transportation
C) transportation and distribution
D) absorption

Question 11

Which of the following is the reason that drugs pass easily though breast milk?

A) it contains low percentages of fats
B) it contains high percentages of fats
C) it contains high percentages of hormones
D) none of the above

Question 12

During pregnancy, which of the following changes does NOT occur:

A) increased renal plasma flow
B) decreased drug excretions
C) increased glomerular filtration rates
D) increased drug excretion

Question 13

Pregnancy drug categories were developed in 1980 by which of the following organizations?

A) the DEA
B) the CDC
C) the FDA
D) none of the above

Question 14

Controlled human studies may show fetal risks that outweigh any possible benefits of the use of a drug during pregnancy. Which of the following drug categories is best described by the previous sentence?

A) X
B) D
C) B
D) A

Question 15

Which of the following drugs should not be given to women during breastfeeding?

A) cephalosporin
B) cytotoxic drugs
C) minerals
D) A and B

Question 16

Which of the following is a true statement regarding drug metabolism during pregnancy or breastfeeding?

A) it is increased
B) it is decreased
C) it is not changed
D) it is sometimes altered

Question 17

Plasma lipid levels throughout pregnancy are:

A) increased
B) decreased
C) not changed
D) sometimes altered

Question 18

Which of the following antiemetic drugs are generally considered safe in low and infrequent doses during pregnancy?

A) phenothiazines
B) piperazines
C) phenobarbital
D) none of the above

Question 19

Which of the following antidepressants do not appear to cause increased risk for fetal complications during pregnancy?

A) MAOIs
B) tricyclic antidepressants
C) SSRIs
D) tetracyclic antidepressants

Question 20

After the baby is delivered, which of the following medications is required for gestational diabetes?

A) insulin
B) tolbutamide
C) levothyroxine
D) none of the above

Question 21

A serious condition of pregnancy involving convulsions is called __________.

Question 22

The heart rate and blood volume during pregnancy normally __________.

Question 23

Fat soluble drugs easily pass through the __________ into the fetus.

Question 24

Less than __________ percent of the total dose of a drug from the breast milk is ingested by a nursing infant.

Question 25

Many side effects of drugs taken by a pregnant patient can mask their __________ effects.

Question 26

During pregnancy, the usage of benzodiazepines can cause __________ infant syndrome.

Question 27

Some drugs are contraindicated for use during the __________ trimester of pregnancy, while others should not be used at all during pregnancy or lactation.

Question 28

Teratogenic drugs may cause serious __________ or even spontaneous abortion.

Question 29

The __________ phase is completed at about 60 days.

Question 30

Many experts believe that seizures in a pregnant woman can cause fetal __________, which leads to brain damage.

Question 31

High doses of fluoxetine (Prozac ) during pregnancy may cause low __________ __________.

Question 32

Diabetic women, during pregnancy, are at an increased risk of having babies with higher birth weights, or for developing __________.

Question 33

The drugs of choice for preeclampsia are magnesium sulfate, to prevent __________, and hydralazine (to treat hypertension).

Question 34

Drug excretion rates are __________ during pregnancy.

Question 35

Beginning in the __________ trimester, arterial blood pressure increases.

Question 36

Category A drugs in pregnant women show __________ __________ to the fetus.

Question 37

__________ __________ drugs are contraindicated for use in pregnant women, and studies show fetal risk.

Question 38

The use of cocaine during pregnancy causes __________ growth retardation.

Question 39

The adverse fetal effect of meperidine is neonatal __________.

Question 40

Excessive use of phenobarbital may cause neonatal __________ and death.

Question 41

Match the drug with the adverse effect it has on the fetus.

-adrenocortical hormones

A) neonatal bleeding and death
B) neonatal depression
C) renal failure
D) electrolyte imbalance
E) growth retardation

Question 42

Match the drug with the adverse effect it has on the fetus.

-cocaine

A) neonatal bleeding and death
B) neonatal depression
C) renal failure
D) electrolyte imbalance
E) growth retardation

Question 43

Match the drug with the adverse effect it has on the fetus.

-acetaminophen

A) neonatal bleeding and death
B) neonatal depression
C) renal failure
D) electrolyte imbalance
E) growth retardation

Question 44

Match the drug with the adverse effect it has on the fetus.

-meperidine

A) neonatal bleeding and death
B) neonatal depression
C) renal failure
D) electrolyte imbalance
E) growth retardation

Question 45

Match the drug with the adverse effect it has on the fetus.

-phenobarbital (high doses)

A) neonatal bleeding and death
B) neonatal depression
C) renal failure
D) electrolyte imbalance
E) growth retardation

Question 46

Match the drug to its indication for use.

-lithium

A) hormone replacement therapy
B) anticoagulant
C) anticonvulsant
D) antibiotic
E) antimanic

Question 47

Match the drug to its indication for use.

-tetracycline

A) hormone replacement therapy
B) anticoagulant
C) anticonvulsant
D) antibiotic
E) antimanic

Question 48

Match the drug to its indication for use.

-phenytoin

A) hormone replacement therapy
B) anticoagulant
C) anticonvulsant
D) antibiotic
E) antimanic

Question 49

Match the drug to its indication for use.

-diethylstilbestrol

A) hormone replacement therapy
B) anticoagulant
C) anticonvulsant
D) antibiotic
E) antimanic

Question 50

Match the drug to its indication for use.

-coumarin

A) hormone replacement therapy
B) anticoagulant
C) anticonvulsant
D) antibiotic
E) antimanic