Deck 9: Drug Therapy for Seizures

Question 1

An excessive discharge of cortical neuron activity is called:

A) electrical threshold
B) action potential
C) seizures
D) none of the above

Answer 1

seizures

Question 2

Tonic-clonic seizures are also called:

A) status epilepticus
B) absence seizures
C) petit mal seizures
D) grand mal seizures

Answer 2

grand mal seizures

Question 3

Which of the following anticonvulsants are also used for the treatment of skeletal muscle spasms, alcohol withdrawal symptoms, and anxiety?

A) hydantoins
B) succinimides
C) benzodiazepines
D) barbiturates

Answer 3

benzodiazepines

Question 4

Fosphenytoin is parenterally used for control of which of the following seizures?

A) status epilepticus
B) absence seizures
C) petit mal seizures
D) grand mal seizures

Question 5

Which of the following drugs may cause gingival hyperplasia?

A) penicillin and barbiturates
B) penicillin and benzodiazepines
C) phenytoin and barbiturates
D) phenytoin and succinimides

Question 6

Which of the following agents is classified as phenytoin-like drugs?

A) carbamazepine and valproic acid
B) ethosuximide and methsuximide
C) fosphenytoin and phenytoin sodium
D) clorazepate and diazepam

Question 7

In general, the mechanisms of action of phenytoin-like agents resemble the mechanism of action of:

A) ethosuximide
B) phenobarbital
C) phensuximide
D) phenytoin

Question 8

Which of the following is generally considered to be the safest of the succinimide drugs?

A) phensuximide
B) ethosuximide
C) methsuximide
D) none of the above

Question 9

The succinimides are contraindicated in patients with:

A) bone marrow depression
B) renal dysfunction
C) liver failure
D) all of the above

Question 10

Which of the following is an example of complex seizures?

A) infantile spasms
B) psychomotor
C) myoclonic
D) petit mal

Question 11

A symptom occurs at the onset of a partial epileptic seizure is called:

A) convulsion
B) epilepsy
C) status epilepticus
D) aura

Question 12

Generalized seizures that do not involve motor convulsions are also referred to as:

A) petit mal
B) grand mal
C) partial
D) Jacksonian

Question 13

An emergency situation characterized by continual seizure activity with no interruptions is called:

A) grand mal
B) myoclonic
C) status epilepticus
D) tonic-clonic

Question 14

Which of the following have multiple foci that may cause loss of consciousness?

A) generalized seizures
B) partial seizures
C) absence seizures
D) none of the above

Question 15

Which of the following anticonvulsant drugs are useful for a wide range of seizure types?

A) succinimides
B) phenytoin-like drugs
C) benzodiazepines
D) barbiturates

Question 16

Which of the following drugs is also used for prevention of migraine headaches and treatment of bipolar disorder?

A) valproic acid
B) clonazepam
C) ethosuximide
D) phenytoin

Question 17

Which of the following phenytoin-like drugs should be used with caution in older adults and in patients with a history of cardiac disease?

A) valproic acid
B) carbamazepine
C) lamotrigine
D) none of the above

Question 18

Which of the following is the mechanism of action of succinimides?

A) They delay the entry of copper into neurons.
B) They delay the entry of potassium into skeletal muscles.
C) They delay the entry of calcium into neurons by blocking calcium channels.
D) None of the above.

Question 19

Which of the following is a general seizure?

A) partial
B) myoclonic
C) Jacksonian
D) autonomic

Question 20

Atonic seizures are also called:

A) grand mal
B) petit mal
C) akinetic
D) Jacksonian

Question 21

Abnormal discharge of the brain neurons that causes alteration of motor activity is called a __________.

Question 22

The old term for recurrent seizures is __________.

Question 23

Seizures are a group of disorders that are characterized by hyperexcitability of neurons in the __________.

Question 24

Seizure disorders are classified by the __________ in the brain and their clinical features.

Question 25

Generalized seizures have __________ foci that may cause loss of consciousness.

Question 26

Partial seizures have a single or focal __________.

Question 27

Continuous seizures without __________ of consciousness are termed status epilepticus.

Question 28

The most useful anticonvulsants are barbiturates and __________.

Question 29

Valproic acid, carbamazepine, and phenytoin are the drugs of choice for __________ __________ seizures.

Question 30

Ethosuximide and valproic acid are the drugs of choice for __________ seizures.

Question 31

The drugs of first choice for __________ seizures are carbamazepine, phenytoin, and lamotrigine.

Question 32

Intravenous phenytoin for status epilepticus must be done carefully because it may cause __________.

Question 33

Barbiturates are chemical derivatives of __________ acid.

Question 34

Barbiturates are classified as either Schedule __________ or __________ medications.

Question 35

The most recognizable and used drug in the hydantoin class is __________.

Question 36

Gingival hyperplasia is one of the adverse effects of __________.

Question 37

The terms epilepsy, convulsions, and seizures are commonly used __________.

Question 38

Partial seizures may or may not involve altered __________.

Question 39

Valproic acid is used for treatment of seizures. It has also been used for the prevention of migraine headaches and the treatment of __________ disorder.

Question 40

Hydantoins act by desensitizing __________ channels in the central nervous system responsible for neuronal responsiveness.

Question 41

Match the generic name to the trade name.

-carbamazepine

A)Dilantin
B)Milontin
C)Tranxene
D)Cerebyx
E)Klonopin
F)Cleontin
G)Felbatol
H)Zarontin
I)Tegretol
J)Depakene

Question 42

Match the generic name to the trade name.

-valporic acid

A)Dilantin
B)Milontin
C)Tranxene
D)Cerebyx
E)Klonopin
F)Cleontin
G)Felbatol
H)Zarontin
I)Tegretol
J)Depakene

Question 43

Match the generic name to the trade name.

-ethosuximide

A)Dilantin
B)Milontin
C)Tranxene
D)Cerebyx
E)Klonopin
F)Cleontin
G)Felbatol
H)Zarontin
I)Tegretol
J)Depakene

Question 44

Match the generic name to the trade name.

-felbamate

A)Dilantin
B)Milontin
C)Tranxene
D)Cerebyx
E)Klonopin
F)Cleontin
G)Felbatol
H)Zarontin
I)Tegretol
J)Depakene

Question 45

Match the generic name to the trade name.

-fosphenytoin

A)Dilantin
B)Milontin
C)Tranxene
D)Cerebyx
E)Klonopin
F)Cleontin
G)Felbatol
H)Zarontin
I)Tegretol
J)Depakene

Question 46

Match the generic name to the trade name.

-clorazepate

A)Dilantin
B)Milontin
C)Tranxene
D)Cerebyx
E)Klonopin
F)Cleontin
G)Felbatol
H)Zarontin
I)Tegretol
J)Depakene

Question 47

Match the generic name to the trade name.

-methsuximide

A)Dilantin
B)Milontin
C)Tranxene
D)Cerebyx
E)Klonopin
F)Cleontin
G)Felbatol
H)Zarontin
I)Tegretol
J)Depakene

Question 48

Match the generic name to the trade name.

-clonazepam

A)Dilantin
B)Milontin
C)Tranxene
D)Cerebyx
E)Klonopin
F)Cleontin
G)Felbatol
H)Zarontin
I)Tegretol
J)Depakene

Question 49

Match the generic name to the trade name.

-phensuximide

A)Dilantin
B)Milontin
C)Tranxene
D)Cerebyx
E)Klonopin
F)Cleontin
G)Felbatol
H)Zarontin
I)Tegretol
J)Depakene

Question 50

Match the generic name to the trade name.

-phenytoin

A)Dilantin
B)Milontin
C)Tranxene
D)Cerebyx
E)Klonopin
F)Cleontin
G)Felbatol
H)Zarontin
I)Tegretol
J)Depakene