Deck 5: The Pharmacology and Physiology of Drug Use
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Deck 5: The Pharmacology and Physiology of Drug Use
1
The part of the brain distinguishing humans from other mammals is the
A) brainstem
B) cerebellum
C) cerebral cortex
D) medulla
A) brainstem
B) cerebellum
C) cerebral cortex
D) medulla
C
2
Homeostasis is maintained by the
A) hypothalamus
B) midbrain
C) pons
D) medulla
A) hypothalamus
B) midbrain
C) pons
D) medulla
A
3
The relationship or interaction between drugs and living organisms is referred to as
A) physiology
B) pharmacology
C) homeostasis
D) neurohormonal balance
A) physiology
B) pharmacology
C) homeostasis
D) neurohormonal balance
B
4
RAS affects
A) sleep
B) attention
C) arousal
D) all of the above
A) sleep
B) attention
C) arousal
D) all of the above
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5
Epinephrine, dopamine, and norepinephrine are all examples of
A) hormonal modulators
B) cCatecholamines
C) neurotransmitters found only in the autonomic nervous system
D) neurotransmitters not secreted into the synapse
A) hormonal modulators
B) cCatecholamines
C) neurotransmitters found only in the autonomic nervous system
D) neurotransmitters not secreted into the synapse
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6
A reduction of ACH receptors in the brain has been linked to what disease?
A) Alzheimer's disease
B) Mmultiple sclerosis
C) Mmuscular dystrophy
D) Eepilepsy
A) Alzheimer's disease
B) Mmultiple sclerosis
C) Mmuscular dystrophy
D) Eepilepsy
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7
Which of the following neurotransmitters plays a role in regulating sensory perception, eating, pain, sleep, and body temperature?
A) Aacetylcholine
B) Eepinephrine
C) Nnorepinephrine
D) Sserotonin
A) Aacetylcholine
B) Eepinephrine
C) Nnorepinephrine
D) Sserotonin
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8
Which of the following neurotransmitters acts as an excitatory transmitter in the skeletal muscles, but functions as an inhibitory transmitter in the heart muscle?
A) Nnorepinephrine
B) Eepinephrine
C) Aacetylcholine
D) Sserotonin
A) Nnorepinephrine
B) Eepinephrine
C) Aacetylcholine
D) Sserotonin
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9
In order for an electrical message to be sent from the axon of one neuron to the dendrite of another neuron, it must transverse a space called the
A) myelin sheath
B) synapse
C) neuron gap
D) neurilemma
A) myelin sheath
B) synapse
C) neuron gap
D) neurilemma
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10
_______allow nerve impulses to be transmitted to the cell body.
A) aAxons
B) Ccell bodyies
C) Mmyelin sheaths
D) Ddendrites
A) aAxons
B) Ccell bodyies
C) Mmyelin sheaths
D) Ddendrites
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11
Before ACH can be inactivated, _______ must be present.
A) vitamins
B) opium
C) cholinesterase
D) citrus juice
A) vitamins
B) opium
C) cholinesterase
D) citrus juice
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12
It is questionable whether _________ is/are truly (a) neurotransmitter(s) since it/ they appear(s) to modulate the activity of neurotransmitters.
A) peptides
B) acetylcholine
C) serotonin
D) Catecholamines
A) peptides
B) acetylcholine
C) serotonin
D) Catecholamines
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13
Epinephrine is also known as
A) acetyl salicylic acid
B) acetaminophen
C) adrenaline
D) noradrenalin
A) acetyl salicylic acid
B) acetaminophen
C) adrenaline
D) noradrenalin
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14
To synthesize serotonin, high levels of what amino acid is needed?
A) Ttryptophan
B) pPeptides
C) Aacetic acid
D) aAcetaminophen
A) Ttryptophan
B) pPeptides
C) Aacetic acid
D) aAcetaminophen
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15
The neurological disorder Huntington's ChoreaHuntington's chorea has been linked to what neurotransmitter?
A) Sserotonin
B) aAcetylcholine
C) eEpinephrine
D) Ggamma-aminobutyric acid
A) Sserotonin
B) aAcetylcholine
C) eEpinephrine
D) Ggamma-aminobutyric acid
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16
Nornadrenaline is also called
A) epinephrine
B) serotonin
C) norepinephrine
D) dopamine
A) epinephrine
B) serotonin
C) norepinephrine
D) dopamine
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17
The __________ system serves as the emotional center of the brain.
A) reticular activating
B) limbic
C) autonomic
D) peripheral
A) reticular activating
B) limbic
C) autonomic
D) peripheral
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18
Which of the following neurotransmitters is released into the blood-stream during times of stress?
A) Nnorepinephrine
B) Sserotonin
C) Ddopamine
D) eEpinephrine
A) Nnorepinephrine
B) Sserotonin
C) Ddopamine
D) eEpinephrine
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19
Which of the following neurotransmitters is thought to play a significant role in emotional, mental, and motor functions?
A) Sserotonin
B) Ddopamine
C) Eepinephrine
D) Aacetylcholine
A) Sserotonin
B) Ddopamine
C) Eepinephrine
D) Aacetylcholine
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20
A nerve cell is referred to as a
A) glial cell
B) dendrite
C) neuron
D) neurilemma
A) glial cell
B) dendrite
C) neuron
D) neurilemma
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21
The user's psychological make-up, personality, mood, and expectations when using drugs is referred to as
A) set
B) setting
C) habituation
D) dominance
A) set
B) setting
C) habituation
D) dominance
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22
Drugs that cause damage to the fetus are called
A) carcinogenic
B) teratogenic
C) psychogenic
D) somatogenic
A) carcinogenic
B) teratogenic
C) psychogenic
D) somatogenic
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23
Alcohol can cause the heart muscle to
A) degenerate
B) induce cardiac arrhythmia
C) increase blood pressure
D) all of the above
A) degenerate
B) induce cardiac arrhythmia
C) increase blood pressure
D) all of the above
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24
The peripheral nervous system consists of the
A) ventral and dorsal systems
B) autonomic and somatic systems
C) distal and medial systems
D) sensory and muscular systems
A) ventral and dorsal systems
B) autonomic and somatic systems
C) distal and medial systems
D) sensory and muscular systems
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25
The medulla and pons are part of the
A) periventricular system
B) reticular activating system
C) cerebral cortex
D) brain stem
A) periventricular system
B) reticular activating system
C) cerebral cortex
D) brain stem
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26
The amount of a drug needed to produce a specific response is the
A) threshold dose
B) safety dose
C) marginal dose
D) effective dose
A) threshold dose
B) safety dose
C) marginal dose
D) effective dose
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27
The endocrine is controlled by the
A) hypothalamus
B) pons
C) medulla
D) limbic system
A) hypothalamus
B) pons
C) medulla
D) limbic system
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28
Why is drug action more prolonged in infants and the elderly?
A) the drugs are absorbed quicker
B) these groups have less neurons
C) they these groups are less able to metabolize and excrete drugs
D) these groups produce more neurotransmitters
A) the drugs are absorbed quicker
B) these groups have less neurons
C) they these groups are less able to metabolize and excrete drugs
D) these groups produce more neurotransmitters
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29
When a user feels the desired effects from lesser amounts of the drug, it is referred to as what type of tolerance?
A) Ppharmacological
B) Bbehavioral
C) Rreverse
D) cCross
A) Ppharmacological
B) Bbehavioral
C) Rreverse
D) cCross
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30
Regulating vital functions is a function of the
A) periventricular system
B) basal ganglia
C) brain stem
D) reticular activating system
A) periventricular system
B) basal ganglia
C) brain stem
D) reticular activating system
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31
Which of the following terms refers to a drug's ability to produce an effect relative to other drugsdrugs?
A) pPurity
B) Ppotency
C) Ppotentiated
D) Ssynergism
A) pPurity
B) Ppotency
C) Ppotentiated
D) Ssynergism
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32
Tolerance for alcohol lessens as people
A) grow
B) think
C) feel
D) age
A) grow
B) think
C) feel
D) age
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33
When the body adjusts or compensates to the presence of a particular drug, the process is referred to as
A) behavioral tolerance
B) cross tolerance
C) pharmacological tolerance
D) reverse tolerance
A) behavioral tolerance
B) cross tolerance
C) pharmacological tolerance
D) reverse tolerance
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34
Drugs that negate the effect of other drugs are
A) synergistic drugs
B) antagonistic drugs
C) anti-elixir drugs
D) interactive drugs
A) synergistic drugs
B) antagonistic drugs
C) anti-elixir drugs
D) interactive drugs
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35
When an individual learns to adjust to the presence of a drug, what type of tolerance does that person exhibit?
A) pPharmacological
B) Bbehavioral
C) Rreverse
D) Ccross
A) pPharmacological
B) Bbehavioral
C) Rreverse
D) Ccross
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36
When tolerance to one drug results in tolerance to another drug, it is referred to as what type of tolerance?
A) Ppharmacological
B) Bbehavioral
C) Rreverse
D) Ccross
A) Ppharmacological
B) Bbehavioral
C) Rreverse
D) Ccross
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37
The smallest amount of a drug to produce an effect is referred to as the
A) effective dose
B) threshold dose
C) safety dose
D) marginal dose
A) effective dose
B) threshold dose
C) safety dose
D) marginal dose
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38
Alcohol and aspirin can be harmful to the gastrointestinal system because the combination can cause
A) diarrhea
B) constipation
C) excessive internal bleeding
D) hemorrhoids
A) diarrhea
B) constipation
C) excessive internal bleeding
D) hemorrhoids
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39
The sympathetic and parasympathetic nervous systems are branches of what larger system?
A) Pperiventricular system
B) Ssomatic nervous system
C) Aautonomic nervous system
D) Rreticular activating system
A) Pperiventricular system
B) Ssomatic nervous system
C) Aautonomic nervous system
D) Rreticular activating system
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40
Antagonistic drugs negate the effects of other drugs.
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41
The sympathetic and parasympathetic branches often work opposed to each other.
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42
Catecholamines affect one's emotional state.
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43
The "Rrunner's high" is due to epinephrine.
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44
Whether behaviors are viewed as rewards or punishment stems from the reticular activating system.
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45
Dendrites allow nerve impulses to be transmitted away from the cell body.
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46
Tryptophan decreases the brain production of serotonin.
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47
The medial forebrain bundle is tied to pleasure and reward.
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48
Inhalation administration of a drug is a very ineffective way to get a drug into the body.
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49
Drugs that produce profound and intense effects and act quickly are more likely to be abused.
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50
Oral administration is the most effective way to get a drug into the body and absorbed.
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51
Elderly women are more likely thenthan men to be at risk for drug -related problems since they receive more prescriptions.
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52
Reverse tolerance means that a drug user will feel the desired effects with less amounts of the drug.
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53
Infants and the elderly are two groups least sensitive to the effects of drugs.
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54
The possibility of a toxic reaction is decreased when drugs are stored in the adipose tissue.
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55
Neurons containing acetylcholine are termed cholinergic.
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56
Hormonal differences account for disparate responses to drugs.
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57
Teratogenic refers to drugs that cause damage to the fetus.
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58
When a person has to increase the amount of a drug to achieve the desired effects, they have probably developed a pharmacological tolerance.
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59
How drugs are administered, absorbed, distributed, metabolized, and excreted from the body is affected by drug pharmacology.
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60
How important do you think tolerance is in terms of drug misuse and abuse? Explain why you think it is important.
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61
Discuss the differences between the central nervous system and the peripheral nervous system.
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62
Identify the major neurotransmitters and discuss how each is thought to affect behavior.
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63
Why is it important to have an understanding of neurophysiology to better understand drug use, misuse, misuse, and abuse?
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64
Distinguish between threshold dose, effective dose, and lethal dose.
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65
Have you ever noticed differences between threshold and effective dose in your own use of medications? What does this tell you about variations in dose/response?
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