Question 1

Antipsychotic drugs can result in the production of abnormal movement patterns known as&#10;A) intra-articular symptoms&#10;B) extrapyramidal symptoms&#10;C) spinocerebellar symptoms&#10;D) dorsal column symptoms&#10;E) malignant hyperthermia

Accepted Answer

Antipsychotic drugs can result in extrapyramidal symptoms, which are abnormal movement patterns. This includes tardive dyskinesia, which involves involuntary movements of the face and body, as well as dystonia, parkinsonism, and akathisia. The other options are not associated with antipsychotic medication use.

Question 2

In addition to their ability to affect dopamine receptors,newer &#34;atypical&#34; antipsychotics also exhibit strong ability to ____ certain CNS _____ receptors.&#10;A) block; serotonin&#10;B) stimulate; serotonin&#10;C) block; norepinephrine&#10;D) stimulate; norepinephrine&#10;E) block; dopamine

Accepted Answer

Atypical antipsychotics, also known as second-generation antipsychotics, have a higher affinity for blocking serotonin receptors (specifically 5-HT2A receptors) than traditional first-generation antipsychotics. This is thought to contribute to their decreased side effects compared to older antipsychotics. These medications may also block dopamine receptors, but less strongly than older antipsychotics. They do not typically stimulate serotonin or norepinephrine receptors.

Question 3

Antipsychotics are often used in Alzheimer disease and other cases of dementia&#10;A) to improve cognition and memory&#10;B) to improve balance&#10;C) to help control aggression and agitation&#10;D) to increase vomiting and diarrhea&#10;E) none of the above

Accepted Answer

Antipsychotics are often used in Alzheimer disease and other cases of dementia to help control aggression and agitation, as they have a calming effect on the patient. However, they do not improve cognition and memory and do not have any effect on balance. They can sometimes cause side effects such as vomiting and diarrhea, but this is not their primary purpose in dementia treatment.

Question 4

Tardive dyskinesia is often the most feared motor side effect of antipsychotic drugs because&#10;A) it is associated with muscle atrophy&#10;B) it is associated with osteoporosis&#10;C) it can cause cardiac dysrhythmias&#10;D) it can cause peripheral neuropathies&#10;E) it may be irreversible

Accepted Answer

Tardive dyskinesia is a potentially irreversible movement disorder that can manifest as involuntary repetitive movements such as grimacing, tongue protrusion, and jerking movements of the limbs. It is a serious side effect of long-term antipsychotic use and can be difficult to treat once it develops.

Question 5

All of the following motor side effects are associated with antipsychotic drugs EXCEPT&#10;A) spasticity&#10;B) tardive dyskinesia&#10;C) pseudoparkinsonism&#10;D) akathisia&#10;E) dystonias

Accepted Answer

Spasticity is not typically associated with antipsychotic drugs, while the other motor side effects listed (including tardive dyskinesia, pseudoparkinsonism, akathisia and dystonias) are commonly seen in patients taking antipsychotics.

Question 6

Traditional antipsychotic drugs such as haloperidol and chlorpromazine are _____ receptor ______.&#10;A) dopamine; agonists&#10;B) dopamine; antagonists&#10;C) acetylcholine; agonists&#10;D) acetylcholine; antagonists&#10;E) 5-hydroxytryptamine; agonists

Accepted Answer

Traditional antipsychotic drugs such as haloperidol and chlorpromazine are dopamine receptor antagonists. They work by blocking dopamine receptors in the brain, which reduces the activity of dopamine and helps to alleviate symptoms of psychosis.

Question 7

Newer or &#34;atypical&#34; antipsychotics are often preferred because&#10;A) they bind more effectively to dopamine receptors in the basal ganglia&#10;B) they offer a greater chance of curing schizophrenia&#10;C) they are less expensive than traditional agents&#10;D) they have a reduced risk of causing motor side effects&#10;E) they are available without prescription

Accepted Answer

Newer or "atypical" antipsychotics have a reduced risk of causing motor side effects such as tardive dyskinesia, extrapyramidal symptoms, and dystonia.

Question 8

Schizophrenia appears to be caused primarily by an overactivity of _______ pathways in certain parts of the brain such as the limbic system.&#10;A) dopamine&#10;B) acetylcholine&#10;C) norepinephrine&#10;D) 5-hydroxytryptamine (serotonin)&#10;E) gama-amino butyric acid (GABA)

Accepted Answer

Research has shown that schizophrenia is primarily caused by an overactivity of dopamine pathways in certain parts of the brain, particularly the limbic system. Medications that block dopamine receptors have been effective in treating symptoms of schizophrenia.

Question 9

Patients taking relatively high doses of the more potent antipsychotics may experience catatonia,stupor,rigidity,tremors,and fever.These symptoms comprise a serious disorder known as&#10;A) Horner's syndrome&#10;B) Brown-Sequard syndrome&#10;C) Charcot's syndrome&#10;D) neuroleptic malignant syndrome&#10;E) general adaptation syndrome

Accepted Answer

The symptoms of catatonia, stupor, rigidity, tremors, and fever are indicative of neuroleptic malignant syndrome, which is a serious disorder associated with high doses of potent antipsychotics. Horner's syndrome, Brown-Sequard syndrome, and Charcot's syndrome do not present with such symptoms. The general adaptation syndrome pertains to the body's response to stress.

Deck 8: Antipsychotic Drugs