Deck 8: Identification of Unexpected Antibodies

Question 1

Rabbit erythrocyte stroma removes ____ and antibodies in the P blood group system.

A)Anti-A
B)Anti-B
C)Anti-Leᵃ
D)Anti-Leᵇ

Answer 1

Anti-B

Question 2

Which method is preferred for removing autoantibodies?

A)Autologous absorption
B)Allogenic absorption
C)Cutaneous absorption
D)Pathologic absorption

Answer 2

Autologous absorption

Question 3

Antibody screen is generally performed using ______ different reagent cells.

A)1-2
B)2-3
C)2-4
D)3-4

Answer 3

2-4

Question 4

Which of the following antigens is a high-frequency antigen that is present in more than 99% of all individuals?

A)D
B)k
C)K
D)P1

Question 5

Which drug is not known to cause a positive direct antiglobulin test (DAT)?

A)Aldomet
B)Aspirin
C)Cephalosporin
D)Procainamide

Question 6

Enhancement reagents are also called

A)Antigrams
B)Elutions
C)Potentiators
D)Titrations

Question 7

If the patient has been transfused within the previous ___ month(s),donor cells may still be circulating in the patient's bloodstream.

A)1
B)2
C)3
D)6

Question 8

All of the following are true about enzyme treatment except

A)Can be performed using either a one- or two-step method
B)Destroys IgM antibodies
C)Destroys some antigens
D)Enhances some antigen-antibody reactions

Question 9

An antibody screen cell with the following phenotype,dce/dec,Fy (a-b+),Jk (a+b+),could be used to exclude or rule out which of the following antibodies?

A)Anti-Fyᵃ
B)Anti-Fyᵇ
C)Anti-Jkᵃ
D)Anti-Jkᵇ

Question 10

If the autocontrol is negative and the patient has been transfused or pregnant,then positive reactions in the antibody screen test are likely due to an

A)alloantibody
B)antigen
C)autoantibody
D)anti-drug antibody

Question 11

The results of a titration showed 2+ positive reactions at 1:2,1:4,1:8,and 1:16 dilutions;1+ positive reactions at 1:32 and 1:64 dilutions;and a negative reaction at 1:128 dilution.What would be the titer result reported?

A)16
B)32
C)64
D)128

Question 12

If an individual inherits two antithetical alleles the person is heterozygous and their cells carry ________ of antigen(s).

A)a single dose
B)a double dose
C)a triple dose
D)four doses

Question 13

The k antigen is destroyed by

A)the enzyme bromelin
B)the enzyme pronase
C)a combination of chymotrypsin and trypsin
D)a combination of ficin and pronase

Question 14

In transfusion medicine,what is the definition of neutralization?

A)Inactivation of an antibody by adsorption onto red blood cells
B)Inactivation of an antibody by combination with a soLuᵇle antigen
C)Inactivation of an antigen by a genetic mutation
D)Inactivation of an antigen by combination with a plasma antibody

Question 15

The elution methods best suited for cold-reactive antibodies include all of the following except

A)Digitonin acid
B)Landsteiner and Wiener heat
C)Lui's freeze-thaw
D)Sonication

Question 16

Which antigen is destroyed by ficin?

A)D
B)C
C)Fyᵃ
D)Jkᵃ

Question 17

What is the most common sulfhydryl reagent used in transfusion medicine?

A)Bromelin
B)Chymotrypsin
C)Dithiothreitol
D)Papain

Question 18

The chance of finding a ____ antibody screening cell is very small.

A)dCe/dCe
B)C/e/E/e
C)cis-AB
D)DCe/dce

Question 19

What test is used to determine the phenotype of red blood cells?

A)Antigen typing
B)Direct antiglobulin test
C)Molecular typing
D)Reflex test

Question 20

What equation is used to calculate the frequency of alleles and genotypes within a population?

A)Fisher-Test
B)Hardy-Weinberg
C)Hyde-Park
D)Landsteiner-Wiener