Deck 11: Antimicrobial Drugs

Question 1

Which of the following is not a test to determine the efficacy of an antimicrobial agent against a specific organism?

A)Polymerase chain reaction
B)Kirby-Bauer method
C)Minimal inhibitory concentration method
D)Serum killing power method

Answer 1

A

Question 2

The term bacteriostatic means that bacteria

A)are killed by the antimicrobial drug.
B)show continuous growth.
C)no longer can multiply.
D)no longer cause disease.

Answer 2

C

Question 3

Which of the following is not a common characteristic used in the selection of an antimicrobial drug?

A)Selective toxicity
B)Ease of delivery to the site of infection
C)Ability to administer intravenously
D)Potential for allergic reaction

Answer 3

C

Question 4

All of the following are general metabolic or structural targets for antimicrobial drugs except

A)Lipid synthesis inhibition
B)Protein synthesis inhibition
C)Interference with nucleic acid synthesis
D)Interference with cell wall synthesis

Question 5

An ideal antimicrobial drug will kill harmful microbes without significant damage to the host.This principle is referred to as __________.

Question 6

All of the following are mechanisms of resistance used by microbes except

A)Change in ribosome composition
B)Development of defensive enzymes
C)Increased drug elimination
D)Change in membrane permeability

Question 7

The findings of the antibacterial properties of Penicillium notatum were first published by

A)Mosse.
B)Joubert.
C)Pasteur.
D)Fleming.

Question 8

Which of the following is an antiviral agent?

A)Amantadine
B)Vancomycin
C)Chloramphenicol
D)Macrolides

Question 9

When two antibiotics are given together to increase the therapeutic effect,the phenomenon is referred to as

A)antagonism.
B)mutualism.
C)synergism.
D)parasitism.

Question 10

Which of the following is a synthetic antimicrobial drug?

A)Penicillin G
B)Penicillin V
C)Cephalosporin
D)Quinolone

Question 11

Antimicrobial drugs that adversely affect the red bone marrow are referred to as

A)hepatotoxic.
B)hemotoxic.
C)neurotoxic.
D)nephrotoxic.

Question 12

A drug that kills pathogenic bacteria is referred to as __________.

Question 13

In order for an antimicrobial drug to be able to cross the blood-brain barrier it must be __________ soluble.

Question 14

Most agents that inhibit protein synthesis involve disrupting the process of __________.

Question 15

Another term for the effectiveness of a drug is __________.

Question 16

Which of the following drugs is effective against Candida albicans?

A)Ketoconazole
B)Amphotericin B
C)Griseofulvin
D)Vancomycin

Question 17

Drugs that are effective against gram-positive and gram-negative bacteria,but not all of them,are ________ activity drugs.

A)small-spectrum
B)narrow-spectrum
C)medium-spectrum
D)broad-spectrum

Question 18

Prontosil,a dye,was first used as an antibiotic by

A)Pasteur.
B)Domagk.
C)Bovet.
D)Fleming.

Question 19

Which of the following antimicrobials is effective against mycobacteria?

A)Penicillin
B)Rifampin
C)Erythromycin
D)Cephalosporin

Question 20

Cephalosporins have __________ generations of developed agents.

A)two
B)three
C)four
D)five

Question 21

Match the description below with the correct item from this list.
a.Vancor
b.Vancocin
c.Sansac
d.Cipro
e.Dalacin
f.Rofact
g.Nydrazid
h.Etibi
Isoniazid

Question 22

Match the description below with the correct item from this list.
a.Vancor
b.Vancocin
c.Sansac
d.Cipro
e.Dalacin
f.Rofact
g.Nydrazid
h.Etibi
Rifampin

Question 23

Resistance to only one type of drug may allow resistance to a similar drug; this process is called __________.

Question 24

Match the description below with the correct item from this list.
a.Vancor
b.Vancocin
c.Sansac
d.Cipro
e.Dalacin
f.Rofact
g.Nydrazid
h.Etibi
Clindamycin

Question 25

The range of pathogen type that a given drug is effective against is referred to as the drug's __________.

Question 26

In the MIC method of determining antibiotic effectiveness,the lowest concentration containing no living organisms is called the __________.

Question 27

Match the description below with the correct item from this list.
a.Vancor
b.Vancocin
c.Sansac
d.Cipro
e.Dalacin
f.Rofact
g.Nydrazid
h.Etibi
Erythromycin

Question 28

The zone of inhibition is the result of the __________ method.

Question 29

The assessment of a drug to determine its benefits versus the risks is called the __________.

Question 30

Match the description below with the correct item from this list.
a.Vancor
b.Vancocin
c.Sansac
d.Cipro
e.Dalacin
f.Rofact
g.Nydrazid
h.Etibi
Ethambutol