Deck 55: Toxicology

Question 1

Which of the following chelating agents are used to bind and remove metals?

A)ethylenediaminetetraacetate
B)deferoxamine
C)British anti-Lewisite
D)all of the above

Answer 1

all of the above

Question 2

Which of the following is considered part of pharmacokinetic parameters?
1)half-life
2)volume of distribution
3)clearance rates

A)1, 2, 3
B)1, 2
C)1, 3
D)2, 3

Answer 2

1, 2, 3

Question 3

Most toxins enter the body through what route?

A)skin
B)lungs
C)gastrointestinal tract
D)all of the above

Answer 3

all of the above

Question 4

What type of toxicology focuses on the pathological processes that are caused by the exposure of a patient to a toxin and includes subsequent medical evaluation and treatment of the patient?

A)clinical
B)forensic
C)environmental
D)occupational

Question 5

Cocaine has what window of detection?

A)1 to 6 hours
B)<72 hours
C)<12 to 24 hours
D)2 to 5 days

Question 6

In which of the following situations would an individual not experience a high from cocaine use?
1)smoking
2)snorting
3)applying to skin
4)drinking

A)1, 2, 3, 4
B)1, 4
C)3, 4
D)2, 3

Question 7

Hemodialysis or hemoperfusion may be effective in removing water-soluble toxins that have which of the following characteristics?
1)high molecular weight
2)low volume of distribution
3)low protein binding

A)1, 2, 3
B)2, 3
C)1, 3
D)1, 2

Question 8

Naloxone is an antidote for what type of poisoning?

A)opiates
B)heavy metals
C)digoxin
D)organophosphates

Question 9

Cadmium can be found in what sample types?
1)blood
2)urine
3)hair
4)nails

A)1, 2, 3
B)2, 3
C)1, 4
D)2, 4

Question 10

When considering herbal drugs and toxins, licorice and licorice root can cause which of the following symptoms?
1)hypertension
2)hypokalemia
3)hypotension
4)hyperkalemia

A)1, 2
B)1, 4
C)2, 3
D)3, 4

Question 11

Which of the following individuals would have the highest metabolism of a drug based strictly on age?

A)a newborn
B)a 20-year-old
C)a 60-year-old
D)an 80-year-old

Question 12

Which of the following binds sulfhydryl groups of enzymes and proteins, uncouples oxidative phosphorylation, and can be found in urine, hair, nail, and blood samples?

A)cadmium
B)iron
C)lead
D)arsenic

Question 13

Which of the following is true of neurotoxicity?
1)Neurotoxicity is strictly a slow, insidious process.
2)The effect of one chemical may lead to an increase in neurotransmitters, whereas another inhibits their production or release.
3)A chemical might alter the flow of sodium, potassium, or calcium across ion channels in membranes.
4)With chronic exposure, it may be difficult to determine whether the symptoms are related to toxicity or a disease state.

A)1, 2, 3
B)1, 2, 4
C)1, 3, 4
D)2, 3, 4

Question 14

Which type of toxin induces genetic changes that become inheritable?

A)mutagens
B)teratogens
C)carcinogens
D)both a and b

Question 15

Which of the following drugs shows a relationship between the concentration of the toxin found in the circulation and toxicity?

A)acetaminophen
B)salicylate
C)carbon monoxide
D)all of the above

Question 16

Which of the following is the correct antidote for iron or aluminum poisoning?

A)Digibind
B)dimercaprol
C)deferoxamine
D)naloxone

Question 17

Ginseng can cause toxicity in which of the following sites?

A)heart
B)liver
C)kidney
D)gastrointestinal tract

Question 18

What is the primary means by which most drugs and toxins cross membranes?

A)active transport
B)facilitated transport
C)passive diffusion
D)passage through membrane pores