Deck 11: Bulk Repackaging and Non-Sterile Compounding

Question 1

All of the following are used for mixing compounds except:

A)Mortars and pestles
B)Spatulas
C)Cylindrical graduated cylinders
D)Ointment slabs

Answer 1

C
Various sizes of glass and porcelain mortars and pestles are necessary, depending on the types of ingredients to be prepared. Ointment slabs are used for mixing ointments, as are spatulas. Graduated cylinders are measuring devices.

Question 2

All of the following are reasons to compound medications except:

A)A compound medication is no longer manufactured by a drug company.
B)Compounding a medication saves the patient money.
C)A specialized dose is needed.
D)The patient is allergic to something in the manufactured form.

Answer 2

B
There are several reasons medications need to be compounded by a pharmacy: the medication is no longer manufactured by the drug company; the patient is allergic to a preservative, dye, or other additive in the normal drug; a specialized dosage or strength is needed for a patient with unique needs; combining several medications will increase patient compliance; the patient cannot ingest the normal dosage form; and the medication requires additives to make it more palatable for a patient.

Question 3

Compounding includes:

A)Mixing
B)Reconstituting
C)Packaging
D)All of the above

Answer 3

D
Compounding is the act of mixing, reconstituting, and packaging a drug.

Question 4

USP <795> sets the standards for all of the following dosage forms except:

A)Creams
B)Elixirs
C)Popsicles
D)Intravenous (IV) medications

Question 5

The minimum weighable quantity for a class A balance is _____ mg.

A)6
B)20
C)120
D)250

Question 6

Which one of the following is not a reason for a pharmacy to repackage a bulk medication?

A)Repackaging helps the technicians learn the drug names and strengths.
B)Purchasing a bulk medication is less expensive than purchasing a unit-dosed medication.
C)Certain medications are not available in unit doses.
D)Repackaging may decrease the wait time for the patient to receive the medication.

Question 7

Which of the following ingredients is(are) considered hydrophobic?

A)Ointment
B)Cream
C)Oleaginous base
D)A and B

Question 8

On April 14, 2015, 1000 low-dose (81 mg) aspirin with a manufacturer's expiration date of December 2017 are unit dosed. What BUD should be assigned?

A)October 14, 2015
B)October 31, 2015
C)April 14, 2016
D)December 14, 2016

Question 9

Which of the following statements is(are) true regarding a class A balance?

A)Class A balance is also called a torsion or class III balance.
B)Class A balance is required by most states' boards of pharmacy.
C)Class A balance uses special milligram and gram weights for counterbalance.
D)All of the above statements are true.

Question 10

The water portion of saline solution is called the:

A)Dissolver
B)Solute
C)Solvent
D)Dissolvent

Question 11

Which of the following is not an advantage of blister packing in long-term care facilities?

A)Allows older adult patients to get one dose out of the package without spilling or touching the other doses.
B)Allows the crediting of unused doses if the physician changes the medication.
C)Is less expensive.
D)Identifying missed doses is easy; therefore compliance is increased.

Question 12

All of the following are GMPs for repackaging bulk medication except:

A)Equipment is in good, clean condition.
B)Appropriate packaging is used.
C)Correct beyond-use date (BUD) is assigned.
D)Medication is checked by a technician.

Question 13

What should be done with pill trays that are used for guiding tablets into unit-dose containers after each use?

A)Nothing
B)Clean with alcohol
C)Rinse with water
D)B and C

Question 14

Which of the following is not a taste that may need to be masked in medicines?

A)Sweet
B)Salty
C)Sour
D)Bitter

Question 15

Which of the following statements is(are) true concerning beyond-use dating of compounded nonsterile products?

A)The BUD of the final compound cannot exceed the expiration date of any of the separate components.
B)No nonsterile compounded product can be assigned a BUD longer than 6 months unless documented in the literature.
C)A topical formulation containing water has a 30-day maximum BUD unless documented in the literature.
D)All of the above statements are true.

Question 16

Weights for a class A balance should be handled with:

A)Gloved hands
B)Tweezers
C)Spatula
D)Glassine paper

Question 17

Which organization sets the standards for a nonsterile compounding area?

A)U.S.Food and Drug Administration (FDA)
B)American Society of Health-System Pharmacists (ASHP)
C)United States Pharmacopeia (USP)
D)Drug Enforcement Administration (DEA)

Question 18

GMP means:

A)Good mixing process
B)Good manufacturing process
C)Good manufacturing procedure
D)Good manufacturing practice

Question 19

Which one of the following is not necessary when manually repackaging?

A)Gloves
B)Laboratory coat
C)Hand washing
D)Shoe covers

Question 20

The punch method is:

A)How a medication is removed from foil-backed blister packs
B)Manual filling of capsules with premixed powdered medication
C)Method for making suppositories
D)None of the above

Question 21

When combining two or more ingredients that have different melting points, the ingredients are:

A)Placed in a container and melted together.
B)Melted from the lowest to the highest melting point.
C)Melted from the highest to the lowest melting point.
D)Mixed; the order of mixing is not important.

Question 22

Which of the following methods is not used to prepare suppositories?

A)Hand-rolling
B)Punch
C)Compression
D)Fusion-molding

Question 23

Where could a pharmacy technician find a list of ingredients, preparation methods, safety requirements, BUD information, and references for compounding a product?

A)Recipe book
B)Product book
C)Formulation record
D)Compounding record

Question 24

Which of the following compounding additives maintains the dispersion of finely divided liquid droplets in a liquid vehicle made from two or more immiscible liquids?

A)Disintegrant
B)Lubricant
C)Plasticizer
D)Emulsifying agent

Question 25

What is the smallest volume that can be accurately measured with a 50-mL graduated cylinder?

A)5 mL
B)10 mL
C)20 mL
D)25 mL

Question 26

Where does a technician log information concerning the contents of a particular product that has been compounded?

A)Material safety data sheets (MSDS)
B)Formulation record
C)Compounding record
D)GMP

Question 27

The proper and accurate way to read a graduated cylinder is:

A)At eye level
B)From a distance
C)At the top of the meniscus
D)A and C

Question 28

What type of compounding may be performed away from the specified compounding area?

A)Suppositories
B)Skin creams
C)Reconstitution of antibiotics
D)None of the above

Question 29

Compounded gummy lozenges may include:

A)Glycerinated gelatin and water
B)Fruit flavoring
C)Medicinal drug
D)All of the above

Question 30

Which of the following dosage forms has the highest percentage of solid ingredients?

A)Creams
B)Ointments
C)Suspensions
D)Pastes

Question 31

Which of the following capsules is the largest?

A)000
B)0
C)1
D)5

Question 32

For continuity of measurement with a class A balance, the weights are always placed on the:

A)Right side
B)Left side
C)Weighing boat or paper
D)A and C