Deck 36: Treatment of Viral Infections

Question 1

Antivirals are not virucidal;they are virustatic.

Answer 1

True
Antivirals do not destroy viruses;they are virustatic.

Question 2

Abacavir is a nucleoside reverse transcriptase inhibitor and is an ingredient in the triple antiretroviral therapy that combines abacavir with AZT and _____.

A)didanosine
B)lamivudine
C)emtricitabine
D)saquinavir

Answer 2

B
Abacavir is a nucleoside reverse transcriptase inhibitor.It is an ingredient in the triple antiretroviral therapy that combines abacavir with AZT and lamivudine.

Question 3

Effective treatment of viral infections is dependent upon _____ factors.

A)host
B)virus
C)drug
D)all of the above

Answer 3

D
Effective treatment of viral infections is dependent upon host factors,virus factors,and drug factors.

Question 4

All of the following are classes of antiretrovirals except _____.

A)nucleoside reverse transcriptase inhibitors (NRTIs)
B)non-nucleoside reverse transcriptase inhibitors (NRTIs)
C)acyclic phosphonate nucleotide analog
D)fusion inhibitors

Question 5

Antiviral medications are effective against all viruses.

Question 6

The only drug in the fusion inhibitor class is _____.

A)abacavir
B)enfuvirtide
C)fosamprenavir
D)efavirenz

Question 7

There are eight steps in the HIV life cycle.

Question 8

The mechanism of action of which drug used to treat RSV is not completely understood,but it is believed that the drug increases the mutation rate of the virus leading to a growing number of viruses unable to replicate?

A)ribavirin
B)foscarnet
C)acyclovir
D)penciclovir

Question 9

MATCHING
Match the following drugs with their classes.
a.PEG-intron
b.non-nucleotide reverse transcriptase inhibitors
c.acyclic phosphonate nucleotide analog
d.nucleotide reverse transcriptase inhibitors
e.neuraminidase inhibitor
f.protease inhibitor
interferon

Question 10

The importance of treating herpes simplex virus is the timing of initiation of drug therapy.Severity of the infection and symptoms are reduced only when antiviral therapy is initiated within the first _____ hours of exposure to the virus or onset of symptoms.

A)6-12
B)12-24
C)24-36
D)24-48

Question 11

Interferons are classified as antiviral agents.

Question 12

A good choice of medication therapy for patients with HIV and HBV co-infections is _____.

A)stavudine
B)emtricitabine
C)lamivudine
D)didanosine

Question 13

The FDA requires the manufacturer of _____ to provide a black box warning in the package labeling regarding reports of fatal and non-fatal intracranial hemorrhage.

A)acyclovir
B)tipranavir
C)saquinavir
D)all of the above

Question 14

_____ is associated with fatal liver toxicity and the FDA has required changes in the package labeling to warn of this adverse effect.

A)Nevirapine
B)Efavirenz
C)Delavirdine
D)All of the above

Question 15

Efavirenz is teratogenic and classified in pregnancy category _____.

A)C
B)D
C)X
D)A

Question 16

Human immunodeficiency virus (HIV)is the virus that causes acquired immune deficiency syndrome (AIDS).The virus attacks _____and weakens the immune system.

A)CD4 monocytes
B)CD4 T lymphocytes
C)CD2 T lymphocytes
D)none of the above

Question 17

AIDs "cocktails" are made up of _____ or more medications.

A)1 to 2
B)2 to 3
C)3 or more
D)none of the above

Question 18

Antiretroviral therapy is a life-long commitment and requires strict adherence to treatment regimens.

Question 19

Which drug is not FDA approved,but is used for the treatment of herpes infections?

A)valacyclovir
B)cidofovir
C)acyclovir
D)foscarnet

Question 20

Which of the following drugs is used to treat influenza A?

A)amantadine
B)rifampin
C)rimantidine
D)a and c

Question 21

MATCHING
Match the following drugs with their classes.
a.PEG-intron
b.non-nucleotide reverse transcriptase inhibitors
c.acyclic phosphonate nucleotide analog
d.nucleotide reverse transcriptase inhibitors
e.neuraminidase inhibitor
f.protease inhibitor
nevirapine

Question 22

MATCHING
Match the following drugs with their classes.
a.PEG-intron
b.non-nucleotide reverse transcriptase inhibitors
c.acyclic phosphonate nucleotide analog
d.nucleotide reverse transcriptase inhibitors
e.neuraminidase inhibitor
f.protease inhibitor
cidofovir

Question 23

MATCHING
Match the following drugs with their classes.
a.PEG-intron
b.non-nucleotide reverse transcriptase inhibitors
c.acyclic phosphonate nucleotide analog
d.nucleotide reverse transcriptase inhibitors
e.neuraminidase inhibitor
f.protease inhibitor
didanosine

Question 24

MATCHING
Match the following drugs with their classes.
a.PEG-intron
b.non-nucleotide reverse transcriptase inhibitors
c.acyclic phosphonate nucleotide analog
d.nucleotide reverse transcriptase inhibitors
e.neuraminidase inhibitor
f.protease inhibitor
atazanavir

Question 25

MATCHING
Match the following drugs with their classes.
a.PEG-intron
b.non-nucleotide reverse transcriptase inhibitors
c.acyclic phosphonate nucleotide analog
d.nucleotide reverse transcriptase inhibitors
e.neuraminidase inhibitor
f.protease inhibitor
zanamivir