Deck 14: Antineoplastic Drugs

Question 1

Kaiden is being treated for a brain tumor.He is told that his chemotherapy may result in peripheral nerve damage and myelosupression,which may be so severe that treatment will be limited.To what class of drugs does Kaiden's chemotherapeutic agent likely belong?

A)signal transduction inhibitors
B)alkylating agents
C)mitotic inhibitors
D)antitumor antibiotics

Answer 1

mitotic inhibitors

Question 2

The chemotherapeutic agent paclitaxel that is used as second-line or subsequent therapy in patients with metastatic breast or ovarian carcinoma refractory on conventional chemotherapy is .

A)so well-tolerated that it is often taken in pill form at home
B)a type of alkylating agent
C)structurally different from other available antineoplastic agents
D)rarely associated with serious adverse events

Answer 2

structurally different from other available antineoplastic agents

Question 3

Chanelle has a brain tumor that is causing swelling of her brain.What class of drugs may be used to reduce cerebral edema?

A)colony stimulating factors
B)hormones
C)alkylating agents
D)mitotic inhibitors

Answer 3

hormones

Question 4

Cheyanne has melanoma and is being treated with interferon to .

A)prevent nausea and vomiting
B)boost her immune system response
C)halt tumor growth
D)prevent proliferation of cancer cells

Question 5

Gina is taking tamoxifen to treat her metastatic estrogen receptor-positive breast cancer and is experiencing severe hot flashes.What might be prescribed to help reduce these flashes?

A)an anti-inflammatory
B)an anti-estrogen
C)an antidepressant
D)an antipyretic

Question 6

Lester is being treated for metastatic prostate cancer and is receiving bicalutamide,an oral agent that interferes with the binding of testosterone.To what class of neoplastic agents does bicalutamide belong?

A)antimetabolite
B)antiandrogen
C)antimitotic
D)antiestrogen

Question 7

Your best friend is diagnosed with lymphoma and asks you about what she's read about the side effects of treatments,particularly gastrointestinal effects and hair loss.You explain to her that many drugs used in the treatment of cancer have effects on the gastrointestinal system and hair because they are especially toxic to cells that are ____.

A)rapidly proliferating
B)slow to reproduce
C)DNA-dependent
D)particularly complex

Question 8

Macy's chemotherapy has left her so anemic and prone to infections that treatment must be temporarily halted.What type of drug might Macy be prescribed to help her body produce bone marrow stem cells that divide and develop into red and white blood cells,and platelets?

A)colony stimulating factor
B)monoclonal antibody
C)vaccine
D)signal transduction inhibitor

Question 9

Arthur does not have cancer,but does have severe rheumatoid arthritis that has not been responsive to treatment.What class of antineoplastic agents might be used to treat his rheumatoid arthritis?

A)monoclonal antibody
B)alkylating agent
C)antimetabolite
D)radioisotope

Question 10

Bryant has skin cancer and is being treated with a topical antimetabolite,which is most likely to be .

A)vinorelbine
B)fluorouracil
C)leucovorin
D)cisplatin

Question 11

Emmaline has metastatic breast cancer and the tumor produces excess amounts of a protein called HER2.She is being treated with herceptin.What type of drug is herceptin?

A)antiestrogen
B)colony stimulating factor
C)monoclonal antibody
D)signal transduction inhibitor

Question 12

Seventy-two year-old Adreanna has lung cancer.What semi-synthetic derived from a plant alkaloid is likely to be recommended?

A)doxorubicin
B)paclitaxel
C)vinorelbine
D)cyclophosphamide

Question 13

Marcy is receiving cisplatin for the treatment of ovarian cancer.Cisplatin acts by .

A)interfering with DNA synthesis,repair,and cellular replication
B)preventing the development of a blood supply for tumor growth
C)damaging the DNA needed for cell reproduction
D)binding hormones necessary for tumor growth

Question 14

Annika is in treatment for acute leukemia with an antitumor antibiotic that has lower levels of cardiotoxicity than other antitumor antibiotics.This medication is most likely .

A)doxorubicin
B)vincristine
C)daunorubicin
D)vinblastine

Question 15

Sebastian has chronic myelogenous leukemia and is being given imatinib (Gleevec).Imatinib blocks specific enzymes and growth factor receptors that affect cancer cell proliferation and belongs to the class of drugs called .

A)mitotic inhibitors
B)antitumor antibiotics
C)monoclonal antibodies
D)signal transduction inhibitors

Question 16

Ziva is in treatment for lymphoma with an antitumor antibiotic.She will be closely monitored for signs of .

A)cardiotoxicity
B)immune system hyperactivity
C)peripheral neuropathy
D)development of a secondary cancer

Question 17

Darian is being treated for lymphoma and invariably experiences nausea and vomiting from his chemotherapy.What medication might be useful in minimizing these side effects?

A)imatinib
B)sipuleucel-T
C)tositumomab
D)ondansetron

Question 18

Your friend Reanna asks you about cancer prevention methods that go beyond lifestyle changes.You inform her about Gardasil and Cervarix,which protect against infection by two high risk types of human papillomavirus (HPV).What percentage of cervical cancers,worldwide,are associated with those two types of HPV?

A)70%
B)60%
C)95%
D)80%

Question 19

Mitch is in treatment for lung cancer with doxorubicin.During the infusion,he should be closely monitored for .

A)hypotension
B)seizures
C)intravenous infiltration
D)hypoglycemia

Question 20

What type of drug is used as primary hormonal therapy for metastatic estrogen receptor-positive breast cancer in both men and postmenopausal women,as well as for palliative treatment?

A)antitumor antibiotic
B)antimetabolite
C)antiandrogen
D)antiestrogen

Question 21

Three-year-old Landon has painful sores in his mouth caused by chemotherapy for leukemia.What instructions should his parents be given about oral hygiene?

A)Brush frequently and vigorously to reduce the risk of infection.
B)Brush and use floss twice a day to promote cleanliness.
C)Use swabs to avoid further damage.
D)Use an alcohol-based mouthwash for its antibacterial properties.

Question 22

Rylie is an oncology nurse who is trying to conceive a baby.Is it safe for her to administer cytotoxic chemotherapy?

A)Possibly.She may be able to administer select medications depending on the type of cytoxic drug being administered.
B)Yes,as long as she does not handle them at the time she is ovulating.
C)Yes,as long as she uses standard chemotherapeutical administration precautions.
D)No.Women who are pregnant,breast-feeding,or actively trying to conceive a child should not care for patients receiving cytotoxic drugs.

Question 23

Jessica has advanced ovarian cancer and fluid is building up in her abdomen.She is hospitalized and radiogold is injected into her abdomen.What piece of knowledge should those caring for her have?

A)Care providers should not be concerned about exposure risk because the radiogold is administered by injection.
B)Only women beyond reproductive age should be allowed to care for Jessica.
C)Care providers should wear lead-lined aprons when within five feet of Jessica.
D)Gowns and gloves should be worn when handling patient excreta such as feces,urine,and body secretions.

Question 24

Caoimhe is being treated for breast cancer with a drug that is only administered IV under constant supervision of an oncologist,with frequent monitoring of vital signs,and facilities available for emergency interventions if required.What drug is she receiving?

A)cyclophosphamide
B)cisplatin
C)vincristine
D)paclitaxel

Question 25

Agatha is receiving palliative chemotherapy,which is intended to .

A)prevent recurrence
B)alleviate symptoms
C)halt tumor growth
D)prevent metastases