Deck 9: Medications That Affect Coagulation
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Deck 9: Medications That Affect Coagulation
1
Calcium and vitamin K play vital roles in the process of clot formation.
A)True
B)False
A)True
B)False
True
2
Which one of the following is a microfibrillar collagen?
A)Oxycel
B)Surgicel
C)Avitene
D)NuKnit
A)Oxycel
B)Surgicel
C)Avitene
D)NuKnit
Avitene
3
Drugs that promote clot formation are termed
A)coagulants.
B)anticoagulants.
C)hemostatics.
D)fibrinolytics.
A)coagulants.
B)anticoagulants.
C)hemostatics.
D)fibrinolytics.
coagulants.
4
A medical plan of treatment for thrombosis usually indicates that a clot has formed in a(n)
A)vein.
B)artery.
A)vein.
B)artery.
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5
During the second stage of blood clot formation,__________ is formed.
A)thromboplastin
B)prothrombin
C)thrombin
D)fibrinogen
A)thromboplastin
B)prothrombin
C)thrombin
D)fibrinogen
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6
Agents that inhibit the process of blood clot formation are called
A)coagulants.
B)anticoagulants.
C)hemostatics.
D)thrombolytics.
A)coagulants.
B)anticoagulants.
C)hemostatics.
D)thrombolytics.
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7
Microfibrillar collagen hemostat is derived from
A)bovine corium collagen.
B)purified pork skin.
C)purified beeswax.
D)an astringent plant.
A)bovine corium collagen.
B)purified pork skin.
C)purified beeswax.
D)an astringent plant.
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8
Which one of the following hemostatic agents may be used dry or moist and is available in film,powder,and sponge forms?
A)Chemical hemostatics
B)Oxidized cellulose
C)Avitene microfibrillar collagen hemostat (MCH)
D)Absorbable gelatin
A)Chemical hemostatics
B)Oxidized cellulose
C)Avitene microfibrillar collagen hemostat (MCH)
D)Absorbable gelatin
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9
Which one of the following hemostatic agents promotes platelet aggregation leading to clot formation?
A)Surgicel
B)Avitene
C)Thrombin
D)NuKnit
A)Surgicel
B)Avitene
C)Thrombin
D)NuKnit
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10
During the third stage of blood clot formation,__________ is formed.
A)thromboplastin
B)prothrombin
C)thrombin
D)fibrin
A)thromboplastin
B)prothrombin
C)thrombin
D)fibrin
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11
During the first stage of blood clot formation,__________ is formed.
A)thromboplastin
B)prothrombin
C)thrombin
D)fibrin
A)thromboplastin
B)prothrombin
C)thrombin
D)fibrin
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12
If a blood clot is formed in an artery,which course of treatment is most likely?
A)Medical
B)Surgical
A)Medical
B)Surgical
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13
Which is not a topical hemostatic?
A)Bone wax
B)Tannic acid
C)Silver nitrate
D)Calcium salts
A)Bone wax
B)Tannic acid
C)Silver nitrate
D)Calcium salts
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14
Which one of the following hemostatic agents causes adhesion formation if it comes in contact with nonbleeding tissues?
A)Surgicel
B)Avitene
C)Gelfoam
D)NuKnit
A)Surgicel
B)Avitene
C)Gelfoam
D)NuKnit
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15
Agents that dissolve already formed clots are called
A)coagulants.
B)anticoagulants.
C)hemostatics.
D)thrombolytics.
A)coagulants.
B)anticoagulants.
C)hemostatics.
D)thrombolytics.
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16
Which one of the following is a natural clot-dissolving enzyme in the blood?
A)Fibrin
B)Fibrinogen
C)Fibrinolysin
D)Fibrin stabilizing factor
A)Fibrin
B)Fibrinogen
C)Fibrinolysin
D)Fibrin stabilizing factor
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17
Which one of the following is a form of oxidized regenerated cellulose?
A)Avitene microfibrillar collagen hemostat (MCH)
B)Surgifoam
C)Surgicel Fibrillar
D)Thrombi-Gel
A)Avitene microfibrillar collagen hemostat (MCH)
B)Surgifoam
C)Surgicel Fibrillar
D)Thrombi-Gel
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18
Which of the following is not a form of absorbable gelatin?
A)Gelfilm
B)Gelfoam powder
C)Gelfoam sponge
D)Thrombogen
A)Gelfilm
B)Gelfoam powder
C)Gelfoam sponge
D)Thrombogen
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19
Which of the following is not a form of absorbable collagen sponge?
A)Helistat
B)Instat
C)Hemopad
D)Avitene
A)Helistat
B)Instat
C)Hemopad
D)Avitene
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20
The formation or presence of a blood clot within the vascular system is termed
A)hemostasis.
B)thrombosis.
C)coagulation.
D)aggregation.
A)hemostasis.
B)thrombosis.
C)coagulation.
D)aggregation.
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21
Which one of the following causes a chemical burn to stop capillary bleeding?
A)Silver nitrate
B)Konakion
C)Helistat
D)Heparin
A)Silver nitrate
B)Konakion
C)Helistat
D)Heparin
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22
Which one of the following is not a function of heparin?
A)Inhibition of factor X
B)Breakdown of fibrin
C)Interfering with prothrombin-to-thrombin conversion
D)Interference with platelet aggregation
A)Inhibition of factor X
B)Breakdown of fibrin
C)Interfering with prothrombin-to-thrombin conversion
D)Interference with platelet aggregation
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23
What is the generic name for Coumadin?
A)Warfarin sodium
B)Vitamin K
C)Anistreplase
D)Urokinase
A)Warfarin sodium
B)Vitamin K
C)Anistreplase
D)Urokinase
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24
Which one of the following parenteral anticoagulants is used most often?
A)Protamine sulfate
B)Calcium chloride
C)Enoxaparin sodium
D)Heparin sodium
A)Protamine sulfate
B)Calcium chloride
C)Enoxaparin sodium
D)Heparin sodium
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25
Which form of anticoagulant is used for long-term management of deep vein thrombosis (DVT)?
A)Parenteral
B)Oral
C)Thrombolytics
D)Factor XIII
A)Parenteral
B)Oral
C)Thrombolytics
D)Factor XIII
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26
What is the duration of heparin (in hours)?
A)1 to 2
B)2 to 4
C)6 to 12
D)12 to 24
A)1 to 2
B)2 to 4
C)6 to 12
D)12 to 24
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27
What is the onset of Coumadin?
A)2 or more days
B)8 to 12 days
C)16 to 24 hours
D)12 to 72 hours
A)2 or more days
B)8 to 12 days
C)16 to 24 hours
D)12 to 72 hours
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28
Which one of the following is used to correct deficiencies in the natural clotting mechanism and may be administered preoperatively or intraoperatively?
A)Systemic coagulants
B)Chemical hemostatics
C)Thrombin
D)Collagen hemostatics
A)Systemic coagulants
B)Chemical hemostatics
C)Thrombin
D)Collagen hemostatics
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29
Which one of the following is not a systemic coagulant?
A)Vitamin K
B)Protamine sulfate
C)Calcium salts
D)Hemofil-M
A)Vitamin K
B)Protamine sulfate
C)Calcium salts
D)Hemofil-M
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30
What is the onset of heparin (in minutes)?
A)5
B)10
C)15
D)20
A)5
B)10
C)15
D)20
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31
Anticoagulants are used for any of the following reasons except
A)to prevent pulmonary embolism.
B)to prevent venous thrombosis.
C)to dissolve blood clots causing a myocardial infarction.
D)postoperative prophylactic therapy for patients with a history of arterial stasis.
A)to prevent pulmonary embolism.
B)to prevent venous thrombosis.
C)to dissolve blood clots causing a myocardial infarction.
D)postoperative prophylactic therapy for patients with a history of arterial stasis.
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32
Which systemic coagulant is contraindicated in patients with a history of malignant hyperthermia?
A)Calcium salts
B)Vitamin K
C)Hemofil-M
D)Factor VIII
A)Calcium salts
B)Vitamin K
C)Hemofil-M
D)Factor VIII
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33
Heparin is measured in
A)milliliters.
B)milligrams.
C)units.
D)drams.
A)milliliters.
B)milligrams.
C)units.
D)drams.
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34
Intravenous administration of _________ is associated with anaphylactic reactions and should not be attempted unless no other venue is available.
A)calcium salts
B)vitamin K
C)anti-hemophilic factor (AHF)
D)factor IX
A)calcium salts
B)vitamin K
C)anti-hemophilic factor (AHF)
D)factor IX
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35
Which one of the following drugs is used to reverse the effect of heparin?
A)Enoxaparin sodium
B)Lovenox
C)Calcium chloride
D)Protamine sulfate
A)Enoxaparin sodium
B)Lovenox
C)Calcium chloride
D)Protamine sulfate
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36
Which one of the following hemostatic agents should be used immediately after it is reconstituted?
A)Avitene
B)Instat MCH
C)Thrombostat
D)Helistat
A)Avitene
B)Instat MCH
C)Thrombostat
D)Helistat
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37
Which solution may be used as an irrigation solution at the sterile field during an atrioventricular (AV)fistula insertion?
A)100 units heparin in 3000 mL saline
B)1000 units heparin in 100 mL saline
C)5000 units heparin in 1000 mL saline
D)10,000 units heparin in 100 mL saline
A)100 units heparin in 3000 mL saline
B)1000 units heparin in 100 mL saline
C)5000 units heparin in 1000 mL saline
D)10,000 units heparin in 100 mL saline
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38
Which one of the following hemostatic agents creates a mechanical barrier to control bleeding?
A)Tannic acid
B)Silver nitrate
C)Collastat
D)Bone wax
A)Tannic acid
B)Silver nitrate
C)Collastat
D)Bone wax
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39
What is the duration of Coumadin?
A)8 to 12 days
B)16 to 24 hours
C)2 to 5 days
D)12 to 72 hours
A)8 to 12 days
B)16 to 24 hours
C)2 to 5 days
D)12 to 72 hours
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40
Which one of the following is not an oral anticoagulant?
A)Aspirin
B)Coumadin
C)Streptokinase
D)Acetylsalicylic acid
A)Aspirin
B)Coumadin
C)Streptokinase
D)Acetylsalicylic acid
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41
Which group of drugs is given intravenously to dissolve existing blood clots?
A)Parenteral anticoagulants
B)Oral anticoagulants
C)Thrombolytics
D)Factor XIII inhibitors
A)Parenteral anticoagulants
B)Oral anticoagulants
C)Thrombolytics
D)Factor XIII inhibitors
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42
All of the following are topical hemostatics except
A)Gelfoam.
B)surgical.
C)bone wax.
D)vitamin K.
A)Gelfoam.
B)surgical.
C)bone wax.
D)vitamin K.
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43
Hemostatic agents are effective against major arterial or venous bleeding.
A)True
B)False
A)True
B)False
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44
Which one of the following procedures is performed to remove a blood clot?
A)Carotid endarterectomy
B)Arterial embolectomy
C)Venous endarterectomy
D)Open heart surgery
A)Carotid endarterectomy
B)Arterial embolectomy
C)Venous endarterectomy
D)Open heart surgery
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45
A blood clot within an intact blood vessel is called a(n)
A)embolus.
B)thrombus.
C)thrombosis.
D)coagulant.
A)embolus.
B)thrombus.
C)thrombosis.
D)coagulant.
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46
If a venous clot breaks off and travels to the heart,it is called a(n)
A)thrombus.
B)coagulant.
C)embolus.
D)thrombosis.
A)thrombus.
B)coagulant.
C)embolus.
D)thrombosis.
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47
What types of hemostatics are used on areas of capillary bleeding?
A)Subcutaneous
B)Intravenous
C)Intramuscular
D)Topical
A)Subcutaneous
B)Intravenous
C)Intramuscular
D)Topical
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48
Which one of the following agents is a chemical hemostatic?
A)Bone wax
B)Silver nitrate
C)Heparin
D)Vitamin K
A)Bone wax
B)Silver nitrate
C)Heparin
D)Vitamin K
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49
Which one of the following is not a thrombolytic drug?
A)Streptokinase
B)Warfarin
C)Urokinase
D)Alteplase
A)Streptokinase
B)Warfarin
C)Urokinase
D)Alteplase
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50
Which naturally occurring mechanism is the most dominant in blood?
A)Coagulants
B)Vitamin K
C)Anticoagulants
D)Calcium
A)Coagulants
B)Vitamin K
C)Anticoagulants
D)Calcium
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51
Which one of the following agents is a thrombolytic?
A)Vitamin K
B)Heparin
C)Protamine sulfate
D)Streptokinase
A)Vitamin K
B)Heparin
C)Protamine sulfate
D)Streptokinase
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52
How long does the intrinsic pathway take to form a clot?
A)Seconds
B)Minutes
C)Hours
D)Days
A)Seconds
B)Minutes
C)Hours
D)Days
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53
Which one of the following is a systemic anticoagulant?
A)Gelfoam
B)Heparin
C)Vitamin K
D)Avitene
A)Gelfoam
B)Heparin
C)Vitamin K
D)Avitene
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54
Which vitamin serves a vital role in coagulation?
A)K
B)D
C)A
D)C
A)K
B)D
C)A
D)C
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55
Bone wax is used primarily in which one of the following surgical specialties?
A)General surgery
B)Gynecology
C)Neurosurgery
D)Otorhinolaryngology
A)General surgery
B)Gynecology
C)Neurosurgery
D)Otorhinolaryngology
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56
A "net" that traps blood cells to form a clot is called
A)fibrin.
B)thrombin.
C)platelets.
D)plasma.
A)fibrin.
B)thrombin.
C)platelets.
D)plasma.
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57
Avitene must be applied with a __________ instrument.
A)large
B)wet
C)dry
D)warm
A)large
B)wet
C)dry
D)warm
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58
Thrombolytic medications are used to treat all of the following except
A)deep vein thrombosis (DVT).
B)pulmonary embolism (PE).
C)myocardial infarction.
D)hemorrhage.
A)deep vein thrombosis (DVT).
B)pulmonary embolism (PE).
C)myocardial infarction.
D)hemorrhage.
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59
Vitamin K is available as
A)AquaMEPHYTON.
B)protamine sulfate.
C)heparin sodium.
D)warfarin.
A)AquaMEPHYTON.
B)protamine sulfate.
C)heparin sodium.
D)warfarin.
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60
Damage to small blood vessels causes a series of reactions that produce a protein called
A)thrombin.
B)thromboplastin.
C)plasma.
D)fibrin.
A)thrombin.
B)thromboplastin.
C)plasma.
D)fibrin.
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61
Match the following medications with the correct categories.
Oral anticoagulant
A)Alteplase (Activase)
B)Heparin
C)Monsel solution
D)Oxidized regenerated cellulose (Surgicel)
E)Vitamin K (Konakion)
F)Warfarin (Coumadin)
Oral anticoagulant
A)Alteplase (Activase)
B)Heparin
C)Monsel solution
D)Oxidized regenerated cellulose (Surgicel)
E)Vitamin K (Konakion)
F)Warfarin (Coumadin)
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62
Which is an example of a flowable form of absorbable gelatin?
A)Gelfoam
B)Gelfilm
C)Tisseel
D)Floseal
A)Gelfoam
B)Gelfilm
C)Tisseel
D)Floseal
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63
Match the following medications with the correct categories.
Parenteral anticoagulant
A)Alteplase (Activase)
B)Heparin
C)Monsel solution
D)Oxidized regenerated cellulose (Surgicel)
E)Vitamin K (Konakion)
F)Warfarin (Coumadin)
Parenteral anticoagulant
A)Alteplase (Activase)
B)Heparin
C)Monsel solution
D)Oxidized regenerated cellulose (Surgicel)
E)Vitamin K (Konakion)
F)Warfarin (Coumadin)
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64
Match the following medications with the correct categories.
Systemic coagulant
A)Alteplase (Activase)
B)Heparin
C)Monsel solution
D)Oxidized regenerated cellulose (Surgicel)
E)Vitamin K (Konakion)
F)Warfarin (Coumadin)
Systemic coagulant
A)Alteplase (Activase)
B)Heparin
C)Monsel solution
D)Oxidized regenerated cellulose (Surgicel)
E)Vitamin K (Konakion)
F)Warfarin (Coumadin)
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65
Match the following medications with the correct categories.
Thrombolytic
A)Alteplase (Activase)
B)Heparin
C)Monsel solution
D)Oxidized regenerated cellulose (Surgicel)
E)Vitamin K (Konakion)
F)Warfarin (Coumadin)
Thrombolytic
A)Alteplase (Activase)
B)Heparin
C)Monsel solution
D)Oxidized regenerated cellulose (Surgicel)
E)Vitamin K (Konakion)
F)Warfarin (Coumadin)
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66
Which hemostatic agent was developed to treat severe traumatic bleeding on the battlefield?
A)Gelfoam
B)Bone wax
C)QuikClot
D)Silver nitrate
A)Gelfoam
B)Bone wax
C)QuikClot
D)Silver nitrate
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67
Match the following medications with the correct categories.
Hemostatic
A)Alteplase (Activase)
B)Heparin
C)Monsel solution
D)Oxidized regenerated cellulose (Surgicel)
E)Vitamin K (Konakion)
F)Warfarin (Coumadin)
Hemostatic
A)Alteplase (Activase)
B)Heparin
C)Monsel solution
D)Oxidized regenerated cellulose (Surgicel)
E)Vitamin K (Konakion)
F)Warfarin (Coumadin)
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68
Match the following medications with the correct categories.
Chemical hemostatic
A)Alteplase (Activase)
B)Heparin
C)Monsel solution
D)Oxidized regenerated cellulose (Surgicel)
E)Vitamin K (Konakion)
F)Warfarin (Coumadin)
Chemical hemostatic
A)Alteplase (Activase)
B)Heparin
C)Monsel solution
D)Oxidized regenerated cellulose (Surgicel)
E)Vitamin K (Konakion)
F)Warfarin (Coumadin)
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69
A tiny piece of gelfoam used during a tympanoplasty procedure is called a
A)pledget.
B)platelet.
C)gelfilm.
D)floseal.
A)pledget.
B)platelet.
C)gelfilm.
D)floseal.
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70
Which hemostatic agent can be used in the presence of a gram-positive microorganism?
A)Surgicel
B)Gelfoam
C)Avitene
D)Bone wax
A)Surgicel
B)Gelfoam
C)Avitene
D)Bone wax
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