Deck 6: Interactions Between Cells and The Extracellular Environment
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Deck 6: Interactions Between Cells and The Extracellular Environment
1
____________ transport does not require membrane proteins.
A)Facilitated diffusion
B)Bulk
C)Simple diffusion
D)Active
A)Facilitated diffusion
B)Bulk
C)Simple diffusion
D)Active
C
2
____________________ is a term which describes a membrane that allows only certain molecules to penetrate it.
A)Selectively permeable
B)Permeable
C)Porous
D)Countertransport
A)Selectively permeable
B)Permeable
C)Porous
D)Countertransport
A
3
Matrix metalloproteinases
A)degrade the basal lamina.
B)synthesize collagen in the extracellular matrix.
C)may be active in invasive cancer cells.
D)synthesize proteoglycans in the extracellular matrix.
A)degrade the basal lamina.
B)synthesize collagen in the extracellular matrix.
C)may be active in invasive cancer cells.
D)synthesize proteoglycans in the extracellular matrix.
C
4
Simple diffusion is the net diffusion of a solvent.
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5
80% of the extracellular fluid is termed interstitial fluid.
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6
Osmosis and simple diffusion do NOT require the actions of carrier proteins.
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7
Active transport
A)utilizes energy.
B)cannot transport molecules against a concentration gradient.
C)cannot be saturated.
D)requires cofactors.
A)utilizes energy.
B)cannot transport molecules against a concentration gradient.
C)cannot be saturated.
D)requires cofactors.
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8
How much of the extracellular fluid makes up the blood plasma?
A)33%
B)92%
C)20%
D)50%
A)33%
B)92%
C)20%
D)50%
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9
___________________ comprise an important family of enzymes that can break down extracellular matrix proteins but require a zinc ion cofactor.
A)Matrix metallohydrolases
B)Matrix phosphokinases
C)Matrix metalloproteinases
D)None of these choices are correct.
A)Matrix metallohydrolases
B)Matrix phosphokinases
C)Matrix metalloproteinases
D)None of these choices are correct.
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10
Active transport proceeds when energy is expended.
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11
The extracellular matrix is made up of collagen, elastin, and a gel-like ground substance.
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12
What cofactor do matrix metalloproteinases need to be functional?
A)calcium
B)copper
C)chromium
D)zinc
A)calcium
B)copper
C)chromium
D)zinc
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13
________ are a class of glycoproteins that bind to components in the extracellular matrix thereby acting as adhesion molecules between cells and the matrix.
A)Glycocalyces
B)Aquaporins
C)Desmosomes
D)Integrins
A)Glycocalyces
B)Aquaporins
C)Desmosomes
D)Integrins
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14
Proteins that extend from the cytoskeleton within the cell, through the plasma membrane, and into the extracellular matrix are
A)lysosomal proteins.
B)metallo proteins.
C)receptor proteins.
D)integrin proteins.
A)lysosomal proteins.
B)metallo proteins.
C)receptor proteins.
D)integrin proteins.
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15
Diffusion ____________ the entropy of a solution.
A)decreases
B)increases
C)does not change
A)decreases
B)increases
C)does not change
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16
Passive transport of water is known as
A)filtration.
B)osmosis.
C)facilitated diffusion.
D)a water pump.
A)filtration.
B)osmosis.
C)facilitated diffusion.
D)a water pump.
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17
How much of the total body water content is intracellular?
A)50%
B)67%
C)33%
D)80%
A)50%
B)67%
C)33%
D)80%
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18
The process in which waste molecules are removed from the blood by having them diffuse through an artificial porous membrane is called dialysis.
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19
A solution consists of a ____________ which dissolves the _____________.
A)solvent, solute
B)solvent, solid
C)solute, solvent
D)liquid, solid
A)solvent, solute
B)solvent, solid
C)solute, solvent
D)liquid, solid
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20
The majority of water within the body is found in the
A)intracellular compartment.
B)extracellular compartment.
C)blood plasma.
D)interstitial fluid.
A)intracellular compartment.
B)extracellular compartment.
C)blood plasma.
D)interstitial fluid.
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21
A one molar solution would contain 6.02 * 1023 molecules of solute.
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22
The osmotic pressure exerted by a cell would decrease if the cell synthesized more proteins.
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23
The rate of diffusion increases as the concentration gradient increases.
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24
Individuals suffering from cystic fibrosis have defective ____________ ion channels.
A)sodium
B)potassium
C)calcium
D)chloride
A)sodium
B)potassium
C)calcium
D)chloride
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25
___________ g of sucrose (molecular weight = 342g) would be added to 1L of water to produce a 2.5 Osm solution.
A)342
B)500
C)855
D)2.5
A)342
B)500
C)855
D)2.5
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26
Which of the following is able to passively penetrate the plasma membrane?
A)O2
B)small charged particles
C)large polar molecules
D)All of these choices are correct.
A)O2
B)small charged particles
C)large polar molecules
D)All of these choices are correct.
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27
A six molar sucrose (molecular weight = 342g) solution would contain
A)57g sucrose per liter.
B)342g sucrose per liter.
C)1026g sucrose per liter.
D)2052g sucrose per liter.
A)57g sucrose per liter.
B)342g sucrose per liter.
C)1026g sucrose per liter.
D)2052g sucrose per liter.
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28
Edema will result if a person has an abnormally low concentration of plasma proteins.
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29
Ion channels that can be opened by physiological stimuli are said to be
A)polar.
B)aquaporins.
C)hypertonic.
D)gated.
A)polar.
B)aquaporins.
C)hypertonic.
D)gated.
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30
Which of the following cells do NOT normally have many aquaporins in their plasma membranes?
A)kidneys
B)lungs
C)salivary glands
D)skin
A)kidneys
B)lungs
C)salivary glands
D)skin
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31
Diffusion is more rapid in cells with microvilli compared to cells lacking microvilli.
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32
The rate of diffusion is influenced by
A)the concentration gradient.
B)membrane permeability.
C)membrane surface area.
D)All of these choices are correct.
A)the concentration gradient.
B)membrane permeability.
C)membrane surface area.
D)All of these choices are correct.
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33
Hydrophobic molecules usually enter a cell via ___________.
A)osmosis
B)active transport
C)diffusion
D)protein channels
A)osmosis
B)active transport
C)diffusion
D)protein channels
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34
The osmotic pressure of a solution is directly related to its ___________ concentration.
A)water
B)solute
C)solvent
D)matrix
A)water
B)solute
C)solvent
D)matrix
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35
Channels present in the membranes of some cells that allow rapid movement of water are called
A)water tubes.
B)aqueducts.
C)aquaporins
D)streams.
A)water tubes.
B)aqueducts.
C)aquaporins
D)streams.
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36
Gas exchange between the cells and extracellular fluid utilizes active transport.
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37
A 0.5M glucose (molecular weight = 180g) contains ____________ grams of glucose per liter.
A)90
B)180
C)6.02 * 1023
D)360
A)90
B)180
C)6.02 * 1023
D)360
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38
Dialysis uses the process of
A)facilitated diffusion.
B)primary active transport.
C)simple diffusion.
D)secondary active transport.
A)facilitated diffusion.
B)primary active transport.
C)simple diffusion.
D)secondary active transport.
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39
A one molal NaCl solution has the same osmolality as a one molal glucose solution.
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40
Solutes that cannot freely pass through a membrane are said to be
A)hypertonic.
B)osmotically inactive.
C)osmotically active.
D)selectively permeable.
A)hypertonic.
B)osmotically inactive.
C)osmotically active.
D)selectively permeable.
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41
A solution freezing at -1.98 C
A)is hypotonic to plasma.
B)is isotonic to plasma.
C)is hypertonic to plasma.
D)is not related to plasma.
A)is hypotonic to plasma.
B)is isotonic to plasma.
C)is hypertonic to plasma.
D)is not related to plasma.
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42
A cell placed in a 9% saline solution (molecular weight = 58.5g) would
A)lyse.
B)crenate.
C)not change.
D)swell.
A)lyse.
B)crenate.
C)not change.
D)swell.
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43
One mole of solute per liter depresses the freezing point of water by -1.86 C.
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44
Cells placed in hypotonic solutions will
A)decrease in volume.
B)increase intracellular solute concentration.
C)increase in volume.
D)lose water to the solution.
A)decrease in volume.
B)increase intracellular solute concentration.
C)increase in volume.
D)lose water to the solution.
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45
The transport maximum is related to the property known as
A)competition.
B)saturation.
C)specificity.
D)inhibition.
A)competition.
B)saturation.
C)specificity.
D)inhibition.
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46
The amount of water in a cell placed in a 0.8 Osm solution would
A)decrease.
B)increase.
C)remain constant.
A)decrease.
B)increase.
C)remain constant.
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47
Freezing-point depression is a measure of osmolality.
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48
A 0.1 Osm plasma sample would
A)stimulate the action of osmoreceptors.
B)be hypertonic to the cells.
C)stimulate an increase in blood volume.
D)inhibit the release of antidiuretic hormone.
A)stimulate the action of osmoreceptors.
B)be hypertonic to the cells.
C)stimulate an increase in blood volume.
D)inhibit the release of antidiuretic hormone.
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49
Glycosuria occurs when the ____________ of the renal glucose transport protein is exceeded.
A)transport minimum
B)transport maximum
C)saturation level
D)Both transport maximum and saturation level are correct.
A)transport minimum
B)transport maximum
C)saturation level
D)Both transport maximum and saturation level are correct.
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50
Glucose entry into the cell is by facilitated diffusion.
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51
Antidiuretic hormone is released by the posterior pituitary in response to increased plasma osmolality.
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52
Plasma freezes at
A)-1.86 C.
B)-1.00 C.
C)-0.56 C.
D)0.00 C.
A)-1.86 C.
B)-1.00 C.
C)-0.56 C.
D)0.00 C.
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53
The osmolality of plasma is
A)0.3 Osm.
B)0.1 Osm.
C)1.0 Osm.
D)2.0 Osm.
A)0.3 Osm.
B)0.1 Osm.
C)1.0 Osm.
D)2.0 Osm.
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54
A 10% dextrose solution is isotonic to plasma.
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55
What type of intravenous fluid would be given to reduce edema?
A)hypertonic
B)isotonic
C)hypotonic
A)hypertonic
B)isotonic
C)hypotonic
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56
Hypertonic solutions stimulate cellular lysis.
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57
Osmoreceptors are involved in the regulation of blood volume.
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58
Protein carrier mediated transport of molecules display
A)specificity.
B)competition.
C)saturation.
D)All of these choices are correct.
A)specificity.
B)competition.
C)saturation.
D)All of these choices are correct.
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59
Which of the following is NOT true of a person who is dehydrated?
A)plasma osmolality increases
B)hypothalamus stimulates release of ADH
C)ADH causes the kidneys to excrete water
D)increased osmolality causes thirst
A)plasma osmolality increases
B)hypothalamus stimulates release of ADH
C)ADH causes the kidneys to excrete water
D)increased osmolality causes thirst
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60
A solution with an osmolality four times greater than plasma would freeze at ___________.
A)-0.56 C.
B)-1.12 C.
C)-1.68 C.
D)-2.24 C.
A)-0.56 C.
B)-1.12 C.
C)-1.68 C.
D)-2.24 C.
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61
Secondary active transport often occurs as a coupled transport process.
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62
In secondary active transport, if the other substance is moved in the same direction as Na+, it is called
A)cotransport.
B)symport.
C)antiport.
D)Both cotransport and symport are correct.
A)cotransport.
B)symport.
C)antiport.
D)Both cotransport and symport are correct.
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63
Facilitated diffusion of a molecule into a cell would be more rapid if
A)the concentration of the molecule in the cell increased.
B)the concentration of water in the cell decreased.
C)the concentration of the molecule outside the cell increased.
D)the cell was isotonic.
A)the concentration of the molecule in the cell increased.
B)the concentration of water in the cell decreased.
C)the concentration of the molecule outside the cell increased.
D)the cell was isotonic.
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64
Glucose transported via the GLUT carrier is characterized as
A)active transport.
B)passive transport.
C)co-transport.
D)receptor-mediated endocytosis.
A)active transport.
B)passive transport.
C)co-transport.
D)receptor-mediated endocytosis.
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65
Active transport proteins are often regulated by phosphorylation.
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66
The transport of molecules out of the urinary filtrate and into the blood is called
A)absorption.
B)reabsorption.
C)countertransport.
D)symport.
A)absorption.
B)reabsorption.
C)countertransport.
D)symport.
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67
Which of the following is NOT true of hypoglycemia?
A)It can result in death.
B)It may be due to diabetes.
C)It is characterized by high plasma glucose levels.
D)Both it can result in death and it may be due to diabetes are correct.
A)It can result in death.
B)It may be due to diabetes.
C)It is characterized by high plasma glucose levels.
D)Both it can result in death and it may be due to diabetes are correct.
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68
The glucose carrier of skeletal muscle is designated as
A)GLUT2.
B)GLUTSk.
C)GLUT4.
D)GLUT5.
A)GLUT2.
B)GLUTSk.
C)GLUT4.
D)GLUT5.
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69
What type of functional complex will prohibit paracellular transport?
A)tight junctions
B)adherens junctions
C)desmosomes
D)gap junctions
A)tight junctions
B)adherens junctions
C)desmosomes
D)gap junctions
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70
Facilitated diffusion is unable to transport molecules against a concentration gradient.
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71
Desmosomes are a type of junctional complex.
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72
Active transport carriers are also called
A)vesicles.
B)channels.
C)pumps.
D)receptors.
A)vesicles.
B)channels.
C)pumps.
D)receptors.
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73
The Na+/K+ pump
A)is an example of primary active transport.
B)generates a positive membrane potential.
C)actively transports 2 potassium ions out of the cell.
D)actively transports 3 sodium ions into the cell.
A)is an example of primary active transport.
B)generates a positive membrane potential.
C)actively transports 2 potassium ions out of the cell.
D)actively transports 3 sodium ions into the cell.
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74
The calcium pump is also an ATPase enzyme.
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75
Poisoning the Na+/K+ pump would
A)generate a more negative membrane potential.
B)increase cellular permeability to Na+.
C)inhibit secondary active transport.
D)increase cellular permeability to K+.
A)generate a more negative membrane potential.
B)increase cellular permeability to Na+.
C)inhibit secondary active transport.
D)increase cellular permeability to K+.
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76
Poisoning the Na+/K+ pump would cause the volume of the cell to ___________.
A)increase
B)decrease
C)remain the same
A)increase
B)decrease
C)remain the same
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77
The Na+/K+ pump transports _______ into the cell and ________ out of the cell per cycle.
A)3Na+, 2K+
B)2Na+, 3K+
C)3K+, 2Na+
D)2K+, 3Na+
A)3Na+, 2K+
B)2Na+, 3K+
C)3K+, 2Na+
D)2K+, 3Na+
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78
Which of the following is NOT a primary active transport pump?
A)GLUT4
B)calcium pump
C)sodium/potassium pump
D)proton pump
A)GLUT4
B)calcium pump
C)sodium/potassium pump
D)proton pump
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79
Secondary active transport
A)utilizes energy directly.
B)often utilizes symport proteins.
C)always uses the influx of sodium ions.
D)is only important in the kidney.
A)utilizes energy directly.
B)often utilizes symport proteins.
C)always uses the influx of sodium ions.
D)is only important in the kidney.
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80
Which of the following is a function of the steep Na+/K+ gradient across the cell membrane?
A)provides energy for coupled transport
B)creates electrochemical impulses
C)maintains osmotic pressure
D)All of these choices are correct.
A)provides energy for coupled transport
B)creates electrochemical impulses
C)maintains osmotic pressure
D)All of these choices are correct.
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