Deck 4: Enzymes and Energy

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Question
Biological catalysts

A)decrease reaction rates.
B)alter a reaction product.
C)remain unchanged at the end of the reaction.
D)All of these choices are correct.
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Question
During a chemical reaction, a catalyst increases the rate at which the reaction occurs.
Question
Which of the following statements about enzymes is NOT true?

A)Enzymes increase chemical reaction rates.
B)Enzymes are consumed during a chemical reaction.
C)Enzymes decrease the free energy of activation of specific reactions.
D)Enzymes have unique pH and temperature optima.
Question
Ribozymes are RNA molecules that act as

A)hormones.
B)cofactors.
C)enzymes.
D)inhibitors.
Question
The process that yeast uses to make alcohol from glucose is

A)fermentation.
B)aerobic respiration.
C)photosynthesis.
D)catalysis.
Question
Enzymes are specific for a given substrate.
Question
The level of protein structure primarily involved in determining enzyme activity is the

A)primary structure.
B)secondary structure.
C)tertiary structure.
D)quaternary structure.
Question
The rate at which a chemical reaction can be increased is by either ______________ the temperature or ______________ the activation energy.

A)increasing, increasing
B)increasing, decreasing
C)decreasing, decreasing
D)decreasing, increasing
Question
Most enzymes are lipids.
Question
Cell extracts from which organism that could carry out fermentation caused vitalism to be questioned?

A)yeast
B)bacteria
C)amoebae
D)paramecia
Question
The model that describes how an enzyme can adjust its shape to fit the shape of the substrate is the

A)lock-and-key model.
B)enzyme-substrate model.
C)induced-fit model.
D)conformational model.
Question
Which of the following is NOT a characteristic of a catalyst?

A)is not changed itself at the end of the reaction
B)does not change the nature of the reaction
C)can change the final result of the reaction
D)increases the rate of the reaction
Question
Catalysts increase reaction rates by lowering the activation energy of a reaction.
Question
An enzyme elevated in the plasma of men with prostate cancer is

A)alkaline phosphatase.
B)catalase.
C)creatine kinase.
D)acid phosphatase.
Question
The model that explains how an enzyme and substrate fit together is the

A)enzyme-substrate model.
B)lock-and-key model.
C)conformational model.
D)None of these choices are correct.
Question
When an enzyme catalyzes a chemical reaction

A)the enzyme binds to the substrate's active site.
B)the enzyme's active site binds the product.
C)amino acids in the substrate allow for interaction with the product.
D)amino acids in the enzyme's active site interact with substrate molecules.
Question
Enzymes ______________ the rate of a specific chemical reaction.

A)decrease
B)increase
C)have no effect on
Question
In some instances RNA can act as an enzyme.
Question
The substrate binds to the ______________ of the enzyme.

A)allosteric site
B)acidic site
C)neutral site
D)active site
Question
Elevated plasma aldolase could be indicative of

A)muscular dystrophy.
B)pancreatitis.
C)pernicious anemia.
D)prostate cancer.
Question
The pH optima for all digestive enzymes are approximately equal to the pH of blood.
Question
Digestive enzymes which remove hydrogen atoms from their substrates are referred to as

A)dehydrogenases.
B)hydrolases.
C)catalases.
D)peroxidases.
Question
Abnormally high concentration of the BB form of creatine phosphokinase is associated with a myocardial infarction.
Question
Addition of phosphate groups to a particular molecule is catalyzed by

A)transaminases.
B)phosphatases.
C)isomerases.
D)kinases.
Question
Isomers are different forms of an enzyme.
Question
In general, decreased body temperature causes the rate of enzymatic reactions to decrease.
Question
Reactant molecules of enzyme action are called

A)substrates.
B)allosteric inhibitors.
C)cofactors.
D)products.
Question
The MM isoenzyme of creatine phosphokinase is found in skeletal muscle.
Question
Dehydration synthesis reactions are catalyzed by

A)dehydrogenases.
B)hydrolases.
C)isomerases.
D)synthases.
Question
The breakdown of hydrogen peroxide is catalyzed by

A)aldolase.
B)amylase.
C)catalase.
D)kinase.
Question
Which of the following does NOT affect the activity of an enzyme?

A)the organ the enzyme is in
B)concentration of enzyme and substrate molecules
C)concentration of cofactors and coenzymes
D)pH and temperature
Question
Hydrolysis reactions are catalyzed by

A)dehydrogenases.
B)hydrolases.
C)isomerases.
D)synthases.
Question
The pH optimum for enzymes secreted by the stomach is higher than the pH optimum for enzymes secreted by the pancreas.
Question
The enzyme with the lowest pH optimum is

A)acid phosphatase.
B)lipase.
C)monoamine oxidase.
D)pepsin.
Question
Isoenzymes bind different substrates and catalyze different chemical reactions.
Question
The conversion of glucose to galactose is catalyzed by an isomerase.
Question
An enzyme-catalyzed reaction in the body at 50 \circ C will proceed at a faster rate than at 35 \circ C.
Question
The phosphatase found in bone would have a pH optimum that is ______________ than the pH optimum of the phosphatase found in the prostate gland.

A)higher
B)lower
C)the same as
Question
Pyruvate dehydrogenase catalyzes the removal of hydrogen from pyruvic acid.
Question
Elevated plasma amylase could indicate

A)osteitis deformans.
B)a myocardial infarct.
C)obstructive jaundice.
D)a perforated peptic ulcer.
Question
End-product inhibition usually involves allosteric inhibition of an enzyme.
Question
Metal ions such as magnesium or calcium can serve as enzyme

A)coenzymes.
B)ribozymes.
C)substrates.
D)cofactors.
Question
In the reaction (H2O + CO2 -> H2CO3), increasing the concentration of H2O would

A)decrease the concentration of H2CO3.
B)increase the concentration of H2CO3.
C)increase the concentration of CO2.
D)have no effect on either CO2 or H2CO3 concentrations.
Question
A defect in the enzyme which converts phenylalanine into tyrosine is characteristic of the disease

A)phenylketonuria.
B)albinism.
C)lactose intolerance.
D)maple-syrup disease.
Question
At saturation, enzyme activity is maximal.
Question
Active enzymes are often called zymogens.
Question
Regulation of a metabolic pathway by the final product of the pathway is termed

A)allosteric inhibition.
B)end-product inhibition.
C)negative feedback.
D)Both end-product inhibition and negative feedback are correct.
Question
The principle that reversible reactions will be driven from the side of the equation where the concentration is lower to the side where the concentration is higher is known as the law of mass action.
Question
Enzymes in a metabolic pathway act antagonistically to produce a final product.
Question
Which of the following is NOT true about enzymes?

A)As the temperature increases from 25 \circ C to 37 \circ C enzyme activity decreases.
B)Very few enzymes require cofactors.
C)Most enzymes are not sensitive to changes in pH.
D)All of these choices are not true.
Question
A deficiency of dietary copper could limit the activity of some enzymes.
Question
______________ are inactive forms of digestive enzymes.

A)Cofactors
B)Coenzymes
C)Zymogens
D)Both cofactors and zymogens are correct.
Question
Which of the following is NOT true of catalysts?

A)They are unchanged by the reaction catalyzed.
B)They allow endergonic reactions to become exergonic reactions.
C)They increase the amount of energy released by a chemical reaction.
D)All of these choices are not true.
Question
A defect in the enzyme that catalyzes the formation of melanin from DOPA results in

A)phenylketonuria.
B)albinism.
C)lactose intolerance.
D)maple-syrup disease.
Question
In response to increased concentration of the final product of a metabolic pathway

A)all enzymes in the pathway become more active.
B)intermediate enzymes become more active.
C)the final product acts as an allosteric regulator of one enzyme in the pathway.
D)all enzymes in the pathway become less active.
Question
______________ occurs when the product of a metabolic pathway binds to an enzyme and decreases enzymatic activity.

A)Allosteric inhibition
B)End-product inhibition
C)Second messaging
D)Coupling
Question
Addition of substrate when enzyme reaction rate is maximal results in

A)additional product formation.
B)less product formation.
C)no change in product formation.
D)enzyme destruction.
Question
Most enzymatic reactions in the body are one step processes.
Question
Coenzymes are organic molecules that are required for proper enzyme function.
Question
In an enzymatic reaction, when temperature is increased past the point of "optimal temperature," the enzyme starts to

A)increase its catalytic activity.
B)reduce its catalytic activity.
C)increase its allosteric properties.
D)increase product formation.
Question
The greatest increase in entropy occurs

A)when starch is degraded to glucose.
B)when amylase produces maltose.
C)when glucose is converted to galactose.
D)when ATP is synthesized.
Question
Oxidizing agents accept electrons from molecules undergoing reduction.
Question
Free energy is ______________ when exergonic reactions proceed.

A)increased
B)decreased
C)unchanged
Question
Energy transformations increase the entropy of a system is a statement of the

A)first law of thermodynamics.
B)second law of thermodynamics.
C)law of mass action.
D)law of conservation of energy.
Question
Another name for the first law of thermodynamics is the law of conservation of energy.
Question
The flow of energy in living systems is termed

A)entropy.
B)enthalpy.
C)bioenergetics.
D)bioluminescence.
Question
Cellular respiration results in a(n) ______________ in entropy as glucose is broken down to form carbon dioxide.

A)increase
B)decrease
C)no change
Question
The reaction of adenosine diphosphate and phosphate generates adenosine triphosphate and energy.
Question
In bioenergetic pathways, as intermediates are acted upon by enzymes, the ultimate result is the release of

A)lactate.
B)ATP.
C)free energy.
D)enzymes.
Question
Endergonic reactions cause the amount of entropy in the products to be

A)increased.
B)decreased.
C)unchanged.
Question
______________ is the universal energy carrier.

A)Glucose
B)ATP
C)ADP
D)GTP
Question
A ______________ is the amount of heat required to raise the temperature of one cubic centimeter of water one degree on the Celsius scale.

A)specific heat
B)meter
C)boiling point
D)calorie
Question
Exergonic reactions proceed with the release of energy.
Question
Free energy is the only type that can be used to perform cellular work.
Question
The amount of entropy increases as bonds are broken to generate glucose from glycogen.
Question
Energy transformations result in a(n) ______________ in entropy.

A)increase
B)decrease
C)no change
Question
Decreased phenylalanine metabolism causes

A)albinism.
B)hypercholeteremia.
C)lactose intolerance.
D)Tay-Sachs disease.
Question
An inborn error in lipid metabolism may cause all of the following diseases EXCEPT

A)Tay-Sachs disease.
B)homocystinuria.
C)hypercholesteremia.
D)Gaucher's disease.
Question
A food calorie (Calorie) is equivalent to which metric measurement of heat?

A)calorie
B)joule
C)kilocalorie
D)watt
Question
Energy can change forms, but cannot be created or destroyed is a statement of the

A)first law of thermodynamics.
B)second law of thermodynamics.
C)law of mass action.
D)third law of thermodynamics.
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Deck 4: Enzymes and Energy
1
Biological catalysts

A)decrease reaction rates.
B)alter a reaction product.
C)remain unchanged at the end of the reaction.
D)All of these choices are correct.
C
2
During a chemical reaction, a catalyst increases the rate at which the reaction occurs.
True
3
Which of the following statements about enzymes is NOT true?

A)Enzymes increase chemical reaction rates.
B)Enzymes are consumed during a chemical reaction.
C)Enzymes decrease the free energy of activation of specific reactions.
D)Enzymes have unique pH and temperature optima.
B
4
Ribozymes are RNA molecules that act as

A)hormones.
B)cofactors.
C)enzymes.
D)inhibitors.
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k this deck
5
The process that yeast uses to make alcohol from glucose is

A)fermentation.
B)aerobic respiration.
C)photosynthesis.
D)catalysis.
Unlock Deck
Unlock for access to all 97 flashcards in this deck.
Unlock Deck
k this deck
6
Enzymes are specific for a given substrate.
Unlock Deck
Unlock for access to all 97 flashcards in this deck.
Unlock Deck
k this deck
7
The level of protein structure primarily involved in determining enzyme activity is the

A)primary structure.
B)secondary structure.
C)tertiary structure.
D)quaternary structure.
Unlock Deck
Unlock for access to all 97 flashcards in this deck.
Unlock Deck
k this deck
8
The rate at which a chemical reaction can be increased is by either ______________ the temperature or ______________ the activation energy.

A)increasing, increasing
B)increasing, decreasing
C)decreasing, decreasing
D)decreasing, increasing
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9
Most enzymes are lipids.
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10
Cell extracts from which organism that could carry out fermentation caused vitalism to be questioned?

A)yeast
B)bacteria
C)amoebae
D)paramecia
Unlock Deck
Unlock for access to all 97 flashcards in this deck.
Unlock Deck
k this deck
11
The model that describes how an enzyme can adjust its shape to fit the shape of the substrate is the

A)lock-and-key model.
B)enzyme-substrate model.
C)induced-fit model.
D)conformational model.
Unlock Deck
Unlock for access to all 97 flashcards in this deck.
Unlock Deck
k this deck
12
Which of the following is NOT a characteristic of a catalyst?

A)is not changed itself at the end of the reaction
B)does not change the nature of the reaction
C)can change the final result of the reaction
D)increases the rate of the reaction
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13
Catalysts increase reaction rates by lowering the activation energy of a reaction.
Unlock Deck
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k this deck
14
An enzyme elevated in the plasma of men with prostate cancer is

A)alkaline phosphatase.
B)catalase.
C)creatine kinase.
D)acid phosphatase.
Unlock Deck
Unlock for access to all 97 flashcards in this deck.
Unlock Deck
k this deck
15
The model that explains how an enzyme and substrate fit together is the

A)enzyme-substrate model.
B)lock-and-key model.
C)conformational model.
D)None of these choices are correct.
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Unlock for access to all 97 flashcards in this deck.
Unlock Deck
k this deck
16
When an enzyme catalyzes a chemical reaction

A)the enzyme binds to the substrate's active site.
B)the enzyme's active site binds the product.
C)amino acids in the substrate allow for interaction with the product.
D)amino acids in the enzyme's active site interact with substrate molecules.
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Unlock for access to all 97 flashcards in this deck.
Unlock Deck
k this deck
17
Enzymes ______________ the rate of a specific chemical reaction.

A)decrease
B)increase
C)have no effect on
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k this deck
18
In some instances RNA can act as an enzyme.
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19
The substrate binds to the ______________ of the enzyme.

A)allosteric site
B)acidic site
C)neutral site
D)active site
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k this deck
20
Elevated plasma aldolase could be indicative of

A)muscular dystrophy.
B)pancreatitis.
C)pernicious anemia.
D)prostate cancer.
Unlock Deck
Unlock for access to all 97 flashcards in this deck.
Unlock Deck
k this deck
21
The pH optima for all digestive enzymes are approximately equal to the pH of blood.
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k this deck
22
Digestive enzymes which remove hydrogen atoms from their substrates are referred to as

A)dehydrogenases.
B)hydrolases.
C)catalases.
D)peroxidases.
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Unlock Deck
k this deck
23
Abnormally high concentration of the BB form of creatine phosphokinase is associated with a myocardial infarction.
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Unlock for access to all 97 flashcards in this deck.
Unlock Deck
k this deck
24
Addition of phosphate groups to a particular molecule is catalyzed by

A)transaminases.
B)phosphatases.
C)isomerases.
D)kinases.
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k this deck
25
Isomers are different forms of an enzyme.
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k this deck
26
In general, decreased body temperature causes the rate of enzymatic reactions to decrease.
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k this deck
27
Reactant molecules of enzyme action are called

A)substrates.
B)allosteric inhibitors.
C)cofactors.
D)products.
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k this deck
28
The MM isoenzyme of creatine phosphokinase is found in skeletal muscle.
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k this deck
29
Dehydration synthesis reactions are catalyzed by

A)dehydrogenases.
B)hydrolases.
C)isomerases.
D)synthases.
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Unlock for access to all 97 flashcards in this deck.
Unlock Deck
k this deck
30
The breakdown of hydrogen peroxide is catalyzed by

A)aldolase.
B)amylase.
C)catalase.
D)kinase.
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Unlock Deck
k this deck
31
Which of the following does NOT affect the activity of an enzyme?

A)the organ the enzyme is in
B)concentration of enzyme and substrate molecules
C)concentration of cofactors and coenzymes
D)pH and temperature
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k this deck
32
Hydrolysis reactions are catalyzed by

A)dehydrogenases.
B)hydrolases.
C)isomerases.
D)synthases.
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k this deck
33
The pH optimum for enzymes secreted by the stomach is higher than the pH optimum for enzymes secreted by the pancreas.
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k this deck
34
The enzyme with the lowest pH optimum is

A)acid phosphatase.
B)lipase.
C)monoamine oxidase.
D)pepsin.
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Unlock Deck
k this deck
35
Isoenzymes bind different substrates and catalyze different chemical reactions.
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k this deck
36
The conversion of glucose to galactose is catalyzed by an isomerase.
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k this deck
37
An enzyme-catalyzed reaction in the body at 50 \circ C will proceed at a faster rate than at 35 \circ C.
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Unlock Deck
k this deck
38
The phosphatase found in bone would have a pH optimum that is ______________ than the pH optimum of the phosphatase found in the prostate gland.

A)higher
B)lower
C)the same as
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k this deck
39
Pyruvate dehydrogenase catalyzes the removal of hydrogen from pyruvic acid.
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k this deck
40
Elevated plasma amylase could indicate

A)osteitis deformans.
B)a myocardial infarct.
C)obstructive jaundice.
D)a perforated peptic ulcer.
Unlock Deck
Unlock for access to all 97 flashcards in this deck.
Unlock Deck
k this deck
41
End-product inhibition usually involves allosteric inhibition of an enzyme.
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k this deck
42
Metal ions such as magnesium or calcium can serve as enzyme

A)coenzymes.
B)ribozymes.
C)substrates.
D)cofactors.
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Unlock Deck
k this deck
43
In the reaction (H2O + CO2 -> H2CO3), increasing the concentration of H2O would

A)decrease the concentration of H2CO3.
B)increase the concentration of H2CO3.
C)increase the concentration of CO2.
D)have no effect on either CO2 or H2CO3 concentrations.
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Unlock for access to all 97 flashcards in this deck.
Unlock Deck
k this deck
44
A defect in the enzyme which converts phenylalanine into tyrosine is characteristic of the disease

A)phenylketonuria.
B)albinism.
C)lactose intolerance.
D)maple-syrup disease.
Unlock Deck
Unlock for access to all 97 flashcards in this deck.
Unlock Deck
k this deck
45
At saturation, enzyme activity is maximal.
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k this deck
46
Active enzymes are often called zymogens.
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k this deck
47
Regulation of a metabolic pathway by the final product of the pathway is termed

A)allosteric inhibition.
B)end-product inhibition.
C)negative feedback.
D)Both end-product inhibition and negative feedback are correct.
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Unlock for access to all 97 flashcards in this deck.
Unlock Deck
k this deck
48
The principle that reversible reactions will be driven from the side of the equation where the concentration is lower to the side where the concentration is higher is known as the law of mass action.
Unlock Deck
Unlock for access to all 97 flashcards in this deck.
Unlock Deck
k this deck
49
Enzymes in a metabolic pathway act antagonistically to produce a final product.
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Unlock for access to all 97 flashcards in this deck.
Unlock Deck
k this deck
50
Which of the following is NOT true about enzymes?

A)As the temperature increases from 25 \circ C to 37 \circ C enzyme activity decreases.
B)Very few enzymes require cofactors.
C)Most enzymes are not sensitive to changes in pH.
D)All of these choices are not true.
Unlock Deck
Unlock for access to all 97 flashcards in this deck.
Unlock Deck
k this deck
51
A deficiency of dietary copper could limit the activity of some enzymes.
Unlock Deck
Unlock for access to all 97 flashcards in this deck.
Unlock Deck
k this deck
52
______________ are inactive forms of digestive enzymes.

A)Cofactors
B)Coenzymes
C)Zymogens
D)Both cofactors and zymogens are correct.
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Unlock for access to all 97 flashcards in this deck.
Unlock Deck
k this deck
53
Which of the following is NOT true of catalysts?

A)They are unchanged by the reaction catalyzed.
B)They allow endergonic reactions to become exergonic reactions.
C)They increase the amount of energy released by a chemical reaction.
D)All of these choices are not true.
Unlock Deck
Unlock for access to all 97 flashcards in this deck.
Unlock Deck
k this deck
54
A defect in the enzyme that catalyzes the formation of melanin from DOPA results in

A)phenylketonuria.
B)albinism.
C)lactose intolerance.
D)maple-syrup disease.
Unlock Deck
Unlock for access to all 97 flashcards in this deck.
Unlock Deck
k this deck
55
In response to increased concentration of the final product of a metabolic pathway

A)all enzymes in the pathway become more active.
B)intermediate enzymes become more active.
C)the final product acts as an allosteric regulator of one enzyme in the pathway.
D)all enzymes in the pathway become less active.
Unlock Deck
Unlock for access to all 97 flashcards in this deck.
Unlock Deck
k this deck
56
______________ occurs when the product of a metabolic pathway binds to an enzyme and decreases enzymatic activity.

A)Allosteric inhibition
B)End-product inhibition
C)Second messaging
D)Coupling
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Unlock Deck
k this deck
57
Addition of substrate when enzyme reaction rate is maximal results in

A)additional product formation.
B)less product formation.
C)no change in product formation.
D)enzyme destruction.
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Unlock for access to all 97 flashcards in this deck.
Unlock Deck
k this deck
58
Most enzymatic reactions in the body are one step processes.
Unlock Deck
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Unlock Deck
k this deck
59
Coenzymes are organic molecules that are required for proper enzyme function.
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Unlock Deck
k this deck
60
In an enzymatic reaction, when temperature is increased past the point of "optimal temperature," the enzyme starts to

A)increase its catalytic activity.
B)reduce its catalytic activity.
C)increase its allosteric properties.
D)increase product formation.
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Unlock Deck
k this deck
61
The greatest increase in entropy occurs

A)when starch is degraded to glucose.
B)when amylase produces maltose.
C)when glucose is converted to galactose.
D)when ATP is synthesized.
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Unlock Deck
k this deck
62
Oxidizing agents accept electrons from molecules undergoing reduction.
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Unlock Deck
k this deck
63
Free energy is ______________ when exergonic reactions proceed.

A)increased
B)decreased
C)unchanged
Unlock Deck
Unlock for access to all 97 flashcards in this deck.
Unlock Deck
k this deck
64
Energy transformations increase the entropy of a system is a statement of the

A)first law of thermodynamics.
B)second law of thermodynamics.
C)law of mass action.
D)law of conservation of energy.
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Unlock Deck
k this deck
65
Another name for the first law of thermodynamics is the law of conservation of energy.
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k this deck
66
The flow of energy in living systems is termed

A)entropy.
B)enthalpy.
C)bioenergetics.
D)bioluminescence.
Unlock Deck
Unlock for access to all 97 flashcards in this deck.
Unlock Deck
k this deck
67
Cellular respiration results in a(n) ______________ in entropy as glucose is broken down to form carbon dioxide.

A)increase
B)decrease
C)no change
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Unlock for access to all 97 flashcards in this deck.
Unlock Deck
k this deck
68
The reaction of adenosine diphosphate and phosphate generates adenosine triphosphate and energy.
Unlock Deck
Unlock for access to all 97 flashcards in this deck.
Unlock Deck
k this deck
69
In bioenergetic pathways, as intermediates are acted upon by enzymes, the ultimate result is the release of

A)lactate.
B)ATP.
C)free energy.
D)enzymes.
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70
Endergonic reactions cause the amount of entropy in the products to be

A)increased.
B)decreased.
C)unchanged.
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71
______________ is the universal energy carrier.

A)Glucose
B)ATP
C)ADP
D)GTP
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72
A ______________ is the amount of heat required to raise the temperature of one cubic centimeter of water one degree on the Celsius scale.

A)specific heat
B)meter
C)boiling point
D)calorie
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73
Exergonic reactions proceed with the release of energy.
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74
Free energy is the only type that can be used to perform cellular work.
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75
The amount of entropy increases as bonds are broken to generate glucose from glycogen.
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76
Energy transformations result in a(n) ______________ in entropy.

A)increase
B)decrease
C)no change
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77
Decreased phenylalanine metabolism causes

A)albinism.
B)hypercholeteremia.
C)lactose intolerance.
D)Tay-Sachs disease.
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78
An inborn error in lipid metabolism may cause all of the following diseases EXCEPT

A)Tay-Sachs disease.
B)homocystinuria.
C)hypercholesteremia.
D)Gaucher's disease.
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79
A food calorie (Calorie) is equivalent to which metric measurement of heat?

A)calorie
B)joule
C)kilocalorie
D)watt
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80
Energy can change forms, but cannot be created or destroyed is a statement of the

A)first law of thermodynamics.
B)second law of thermodynamics.
C)law of mass action.
D)third law of thermodynamics.
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Unlock Deck
Unlock for access to all 97 flashcards in this deck.