Deck 15: Viruses
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Deck 15: Viruses
1
The stage of viral replication in which the virus binds a cell surface receptor is:
A)Release
B)Penetration
C)Synthesis
D)Attachment
E)Assembly
A)Release
B)Penetration
C)Synthesis
D)Attachment
E)Assembly
D
2
HIV is a:
A)Double-stranded DNA virus
B)Single-stranded RNA virus
C)Single-stranded DNA virus
D)Double-stranded RNA virus
E)Prion
A)Double-stranded DNA virus
B)Single-stranded RNA virus
C)Single-stranded DNA virus
D)Double-stranded RNA virus
E)Prion
B
3
Viruses:
A)Consist of only a single cell
B)Are smaller than cells
C)Consist of multiple cells
D)Contain a nucleus
E)Contain ribosomes
A)Consist of only a single cell
B)Are smaller than cells
C)Consist of multiple cells
D)Contain a nucleus
E)Contain ribosomes
B
4
The type of viral infection in which a virus enters a host cell and then remains dormant (hidden)in a host cell's chromosome is:
A)A rare form of viral infection
B)A transgenic infection
C)A lytic infection
D)A systematic infection
E)A lysogenic infection
A)A rare form of viral infection
B)A transgenic infection
C)A lytic infection
D)A systematic infection
E)A lysogenic infection
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5
A layer of host cell membrane attached to a virus is called:
A)An envelope
B)A protein coat
C)A capsomere
D)A capsid
E)A plasmid
A)An envelope
B)A protein coat
C)A capsomere
D)A capsid
E)A plasmid
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6
A capsid is:
A)A lipid coat of a virus
B)A viral DNA molecule
C)A protein coat of a virus
D)A viral RNA molecule
E)The area in the virus where its genetic information is located
A)A lipid coat of a virus
B)A viral DNA molecule
C)A protein coat of a virus
D)A viral RNA molecule
E)The area in the virus where its genetic information is located
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7
The stage of viral replication in which the host cell produces viral nucleic acids and proteins is:
A)Release
B)Attachment
C)Synthesis
D)Penetration
E)Assembly
A)Release
B)Attachment
C)Synthesis
D)Penetration
E)Assembly
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8
Which of the following diseases is NOT caused by viruses?
A)The common cold and influenza
B)Smallpox and mononucleosis
C)Polio and rabies
D)Aids and warts
E)Diabetes
A)The common cold and influenza
B)Smallpox and mononucleosis
C)Polio and rabies
D)Aids and warts
E)Diabetes
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9
Most viruses:
A)Infect only a few closely related species
B)Only infect animal cells
C)Infect a wide variety of organisms
D)Cannot infect living cells
E)Only infect plant cells
A)Infect only a few closely related species
B)Only infect animal cells
C)Infect a wide variety of organisms
D)Cannot infect living cells
E)Only infect plant cells
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10
The shape of a virus is determined by:
A)Its DNA
B)Its RNA
C)Its envelope
D)Its host
E)Its coat protein organization
A)Its DNA
B)Its RNA
C)Its envelope
D)Its host
E)Its coat protein organization
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11
Viruses that infect bacteria are:
A)Not known to exist
B)Prions
C)Bacteriophages
D)Composed of protein only
E)Also capable of causing disease in humans
A)Not known to exist
B)Prions
C)Bacteriophages
D)Composed of protein only
E)Also capable of causing disease in humans
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12
The stage of viral replication in which the new viruses leave the host cell is:
A)Release
B)Attachment
C)Penetration
D)Synthesis
E)Assembly
A)Release
B)Attachment
C)Penetration
D)Synthesis
E)Assembly
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13
The host range of a virus is:
A)The geographical location in which the virus is found
B)The type of organisms or cells that a virus can infect
C)Determined by receptor molecules on living cells
D)Determined by the prey it feeds on
E)The biome it is found in
A)The geographical location in which the virus is found
B)The type of organisms or cells that a virus can infect
C)Determined by receptor molecules on living cells
D)Determined by the prey it feeds on
E)The biome it is found in
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14
The treating of a viral infection by inoculating the host with a bacterial virus:
A)Is chemotherapy
B)Is phage therapy
C)Is radiation therapy
D)Is antibiotic therapy
E)None of these are correct
A)Is chemotherapy
B)Is phage therapy
C)Is radiation therapy
D)Is antibiotic therapy
E)None of these are correct
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15
The influenza viruses that infect man usually are derived from a type that could also infect:
A)Horses and sheep
B)Cattle and water buffalo
C)Chimpanzees and gorillas
D)Birds and pigs
E)A variety of primates
A)Horses and sheep
B)Cattle and water buffalo
C)Chimpanzees and gorillas
D)Birds and pigs
E)A variety of primates
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16
The stage of viral replication in which viral components are put together to form new viruses is:
A)Release
B)Assembly
C)Attachment
D)Penetration
E)Synthesis
A)Release
B)Assembly
C)Attachment
D)Penetration
E)Synthesis
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17
The type of viral infection in which a virus enters a host cell immediately replicates and causes the host cell to burst is:
A)A rare form of viral infection
B)A transgenic infection
C)A lysogenic infection
D)A lytic infection
E)A systematic infection
A)A rare form of viral infection
B)A transgenic infection
C)A lysogenic infection
D)A lytic infection
E)A systematic infection
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18
The stage of viral replication in which the viral nucleic acid is released inside the cell is:
A)Penetration
B)Release
C)Attachment
D)Synthesis
E)Assembly
A)Penetration
B)Release
C)Attachment
D)Synthesis
E)Assembly
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19
The correct sequence of the stages of viral replication is:
A)Attachment - Synthesis - Penetration - Assembly - Release
B)Penetration - Attachment - Assembly - Synthesis - Release
C)Penetration - Attachment - Synthesis - Release - Assembly
D)Attachment - Penetration - Assembly - Synthesis - Release
E)Attachment - Penetration - Synthesis - Assembly - Release
A)Attachment - Synthesis - Penetration - Assembly - Release
B)Penetration - Attachment - Assembly - Synthesis - Release
C)Penetration - Attachment - Synthesis - Release - Assembly
D)Attachment - Penetration - Assembly - Synthesis - Release
E)Attachment - Penetration - Synthesis - Assembly - Release
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20
The genetic information in viruses:
A)Is found in the nucleus of the virus
B)Is always DNA
C)Can be DNA or RNA
D)Is always RNA
E)Can be replicated outside of a cell
A)Is found in the nucleus of the virus
B)Is always DNA
C)Can be DNA or RNA
D)Is always RNA
E)Can be replicated outside of a cell
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21
Viral DNA inserted into a chromosome of the host is:
A)A carrier
B)A phage
C)A reservoir
D)A prophage
E)A lytic infection
A)A carrier
B)A phage
C)A reservoir
D)A prophage
E)A lytic infection
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22
Viruses are not considered to be alive,yet they share this ability with living cells:
A)They can metabolize food
B)They can evolve
C)They can reproduce on their own
D)They can produce cell membranes
E)They can synthesize proteins
A)They can metabolize food
B)They can evolve
C)They can reproduce on their own
D)They can produce cell membranes
E)They can synthesize proteins
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23
Oral infections with herpes simplex virus 1 can lie dormant in nerve cells for years,and when a patient becomes stressed,the virus is released,forming cold sores on the lips.Why would the virus form a cold sore?
A)To allow it to spread to a new host
B)So that it can mutate and survive an antibiotic treatments
C)To move to another part of the body
D)To avoid the immune system
E)To warn other people that the host is infected
A)To allow it to spread to a new host
B)So that it can mutate and survive an antibiotic treatments
C)To move to another part of the body
D)To avoid the immune system
E)To warn other people that the host is infected
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24
An infectious RNA molecule is a:
A)Virus
B)Virion
C)Viroid
D)Prion
E)Prophage
A)Virus
B)Virion
C)Viroid
D)Prion
E)Prophage
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25
Drugs like Aziodothymidine (AZT):
A)Inhibit viral DNA from inserting into the host chromosome
B)Inhibit the cleaving of proteins needed to make the protein coat of a virus
C)Inhibit host cells from reproducing
D)Inhibit reverse transcriptase
E)Inhibit viruses from entering a host cell
A)Inhibit viral DNA from inserting into the host chromosome
B)Inhibit the cleaving of proteins needed to make the protein coat of a virus
C)Inhibit host cells from reproducing
D)Inhibit reverse transcriptase
E)Inhibit viruses from entering a host cell
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26
Our most potent weapon in the fight against viruses is:
A)Antibiotics
B)Sulfa drugs
C)Gene therapy
D)Surgery
E)Vaccinations
A)Antibiotics
B)Sulfa drugs
C)Gene therapy
D)Surgery
E)Vaccinations
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27
Since viruses have no active methods of entering plant cells,they must rely upon mechanically caused wounds,vegetative propagation of plants,grafting,seed,pollen,and being carried on the mouth parts of chewing insects.Tobacco mosaic virus is most commonly introduced into plants through small wounds caused by handling and by insects chewing on plant parts.What would prevent viruses from easily entering plant cells?
A)The cell wall on the virus
B)The plasma membrane on the plant
C)The cell wall on the plant
D)The plasma membrane on the virus
E)The protein coat on the virus
A)The cell wall on the virus
B)The plasma membrane on the plant
C)The cell wall on the plant
D)The plasma membrane on the virus
E)The protein coat on the virus
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28
HIV:
A)Is a retrovirus
B)Infects most mammals
C)Can be killed with antibiotics
D)Causes liver cancer
E)Can be transmitted through the skin
A)Is a retrovirus
B)Infects most mammals
C)Can be killed with antibiotics
D)Causes liver cancer
E)Can be transmitted through the skin
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29
The Human Immunodeficiency Virus (HIV)only affects a specific class of cells in the immune system called T helper cells,and not other types of T cells.Which is the best explanation for this observation?
A)HIV can only replicate inside of T helper cells
B)Only T helper cells have reverse transcriptase
C)The T helper cells are not necessary for the immune system to fight viral infections
D)Only T helper cells have the correct receptor on their cell surface
E)HIV can only be released from T helper cells
A)HIV can only replicate inside of T helper cells
B)Only T helper cells have reverse transcriptase
C)The T helper cells are not necessary for the immune system to fight viral infections
D)Only T helper cells have the correct receptor on their cell surface
E)HIV can only be released from T helper cells
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30
The enzyme that HIV uses to convert its RNA into DNA is:
A)Reverse transcriptase
B)DNA polymerase
C)RNA polymerase
D)RNA integrase
E)Transcriptase
A)Reverse transcriptase
B)DNA polymerase
C)RNA polymerase
D)RNA integrase
E)Transcriptase
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31
Oral infections with herpes simplex virus 1 can lie dormant in nerve cells for years,and when a patient becomes stressed,the virus is released,forming cold sores on the lips.Where will the virus be while dormant in the nerve cell?
A)Floating in the nerve cell cytoplasm
B)Integrated in the nerve cell chromosomes
C)In the nerve cell membrane
D)Floating outside of the nerve cell, waiting to reinfect it
E)In the blood
A)Floating in the nerve cell cytoplasm
B)Integrated in the nerve cell chromosomes
C)In the nerve cell membrane
D)Floating outside of the nerve cell, waiting to reinfect it
E)In the blood
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32
Oral infections with herpes simplex virus 1 can lie dormant in nerve cells for years,and when a patient becomes stressed,the virus is released,forming cold sores on the lips.In a cold sore,the virus is in which of the following states?
A)Latent
B)Lysogenic
C)Assembly
D)Remissive
E)Asymptomatic
A)Latent
B)Lysogenic
C)Assembly
D)Remissive
E)Asymptomatic
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33
An infectious protein is a:
A)Virus
B)Viroid
C)Prion
D)Virion
E)Prophage
A)Virus
B)Viroid
C)Prion
D)Virion
E)Prophage
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34
Many doctors recommend that all women be vaccinated for HPV before they become sexually active.Which step in the viral life cycle would first be blocked by a vaccine?
A)Attachment
B)Penetration
C)Synthesis
D)Assembly
E)Release
A)Attachment
B)Penetration
C)Synthesis
D)Assembly
E)Release
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35
Hepatitis A and C contain an RNA genome while hepatitis B contains a DNA genome.What could you conclude about these hepatitis viruses?
A)They do not all share a common ancestor
B)They do not all affect the liver
C)They all have the same symptoms
D)They all have the same mode of transmission
E)They all have the same rate of occurrence
A)They do not all share a common ancestor
B)They do not all affect the liver
C)They all have the same symptoms
D)They all have the same mode of transmission
E)They all have the same rate of occurrence
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36
Human Papilloma Virus (HPV)can be transmitted sexually,and causes genital warts and cervical cancer.Why might a virus trigger increased cell growth?
A)To use the cell's mitochondria to perform respiration
B)Viruses are parasites and can only grow on dead cells
C)To protect the virus from the immune system
D)To allow the virus to spread to other people
E)To use the cell's replication machinery to make more virus
A)To use the cell's mitochondria to perform respiration
B)Viruses are parasites and can only grow on dead cells
C)To protect the virus from the immune system
D)To allow the virus to spread to other people
E)To use the cell's replication machinery to make more virus
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37
A patient receiving a protease inhibitor and AZT is probably being treated for an infection by:
A)A bacterium
B)A protozoan
C)A DNA virus
D)A retrovirus
E)A fungus
A)A bacterium
B)A protozoan
C)A DNA virus
D)A retrovirus
E)A fungus
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38
A reason or reasons given by scientists as to why viruses are not considered living organisms include:
A)Viruses do not contain genetic information
B)Viruses do not reproduce on their own
C)Viruses are all smaller than the smallest known cells
D)Viruses do not contain a nucleus
E)Viruses can be frozen and still survive
A)Viruses do not contain genetic information
B)Viruses do not reproduce on their own
C)Viruses are all smaller than the smallest known cells
D)Viruses do not contain a nucleus
E)Viruses can be frozen and still survive
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39
Most antibiotics are not effective against viruses because these antibiotics do which of the following?
A)Inhibit synthesis of cell walls
B)Destroy DNA and RNA
C)Inhibit all protein synthesis
D)Target capsids
E)Inhibit reverse transcriptase
A)Inhibit synthesis of cell walls
B)Destroy DNA and RNA
C)Inhibit all protein synthesis
D)Target capsids
E)Inhibit reverse transcriptase
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40
Oral infections with herpes simplex virus 1 can lie dormant in nerve cells for years,and when a patient becomes stressed,the virus is released,forming cold sores on the lips.While lying dormant the virus is in which of the following states?
A)Lysogenic
B)Symptomatic
C)Latent
D)Replicative
E)Infective
A)Lysogenic
B)Symptomatic
C)Latent
D)Replicative
E)Infective
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41

Given the structure of the anti-HIV drug azidothymidine (AZT),how do you think it blocks viral replication?
A)It blocks RNA synthesis
B)It inhibits host T cells from replicating
C)It inhibits the assembly of new viruses in the cell
D)It blocks DNA synthesis
E)It prevents HIV from entering the cell
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42
Viruses always lack which of the following?
A)A plasma membrane
B)Genetic material
C)A protein coat
D)Organelles
A)A plasma membrane
B)Genetic material
C)A protein coat
D)Organelles
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43
The vaccine against the influenza virus is prepared by treating the virus with detergent.How would this inactivate the virus?
A)By destroying the envelope
B)By destroying the protein coat
C)By destroying the RNA
D)By destroying the DNA
E)By inhibiting viral assembly
A)By destroying the envelope
B)By destroying the protein coat
C)By destroying the RNA
D)By destroying the DNA
E)By inhibiting viral assembly
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44
The influenza virus contains an RNA genome.Every year the common flu vaccine is designed to protect against three different strains of the influenza virus.Why do scientists typically have to make a new vaccine every year?
A)Because our bodies develop resistance to the vaccine and it becomes less effective
B)Because the virus develops resistance to the vaccine
C)Because the virus can mutate into new strains
D)Because people change their habits each year and become susceptible to different strains of the virus
E)Because the common influenza virus can come from many species of animals including cats and dogs
A)Because our bodies develop resistance to the vaccine and it becomes less effective
B)Because the virus develops resistance to the vaccine
C)Because the virus can mutate into new strains
D)Because people change their habits each year and become susceptible to different strains of the virus
E)Because the common influenza virus can come from many species of animals including cats and dogs
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45
Rhinovirus is an RNA virus that causes the common cold and sinus infections.The virus does not contain an envelope.Which of the following is true of a rhinovirus?
A)It does not contain protein or genetic material
B)It does not contain genetic material
C)It does not contain protein
D)It does not contain lipid or protein
E)It does not contain lipid
A)It does not contain protein or genetic material
B)It does not contain genetic material
C)It does not contain protein
D)It does not contain lipid or protein
E)It does not contain lipid
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46
What is the genetic material found in HIV?
A)Protein
B)RNA
C)DNA
D)Lipid
E)Carbohydrate
A)Protein
B)RNA
C)DNA
D)Lipid
E)Carbohydrate
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47
Viruses can infect all higher life forms such as plants and animals,but cannot infect bacteria.
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48
figure 15.4 
Reviewing figure 15.4,which of the following is true of HIV?
A)It contains DNA as its genetic material
B)It replicates in the cytoplasm of cells
C)It lyses cells when it is released
D)It uses reverse transcriptase from the cell to make DNA
E)It is an enveloped virus

Reviewing figure 15.4,which of the following is true of HIV?
A)It contains DNA as its genetic material
B)It replicates in the cytoplasm of cells
C)It lyses cells when it is released
D)It uses reverse transcriptase from the cell to make DNA
E)It is an enveloped virus
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49
Poliomyelitis is an RNA virus that can invade the nervous system and cause paralysis within a matter of hours.Polio has been virtually eliminated world-wide by which of the following?
A)Antibiotics
B)Vaccination
C)Mosquito control
D)Quarantine
E)Improve water quality
A)Antibiotics
B)Vaccination
C)Mosquito control
D)Quarantine
E)Improve water quality
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50
figure 15.4 
SIV causes symptomless infections in monkeys and apes,yet causes AIDS-like disease in chimpanzees.HIV is closely related to SIV and causes AIDS in humans.Which of the following is the best explanation for these observations?
A)Monkeys, apes, and chimpanzees are all genetically very similar
B)The effects of viruses on different species is random
C)Chimpanzees and humans have a more recent common ancestor
D)SIV is most likely lytic in apes and monkeys
E)SIV is most likely latent in chimpanzees

SIV causes symptomless infections in monkeys and apes,yet causes AIDS-like disease in chimpanzees.HIV is closely related to SIV and causes AIDS in humans.Which of the following is the best explanation for these observations?
A)Monkeys, apes, and chimpanzees are all genetically very similar
B)The effects of viruses on different species is random
C)Chimpanzees and humans have a more recent common ancestor
D)SIV is most likely lytic in apes and monkeys
E)SIV is most likely latent in chimpanzees
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51
How did the researchers first know that Marilyn the chimp may be infected with HIV?
A)Because she had HIV RNA in her blood
B)Because she had HIV DNA in her tissues
C)Because she had been used in HIV research
D)Because she had raised antibodies against HIV
E)Because she had symptoms of HIV infection, or AIDS
A)Because she had HIV RNA in her blood
B)Because she had HIV DNA in her tissues
C)Because she had been used in HIV research
D)Because she had raised antibodies against HIV
E)Because she had symptoms of HIV infection, or AIDS
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52
Many viruses are inhibited by antibiotics.
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53
Smallpox is an enveloped virus with a DNA genome.We have eliminated this once deadly virus through an aggressive world-wide vaccination program.Why might a vaccine be successful with smallpox,but not with HIV?
A)Because smallpox is an enveloped virus
B)Because viruses with DNA genomes must replicate inside a host cell
C)Because RNA is more stable than DNA, and is less likely to be destroyed by the vaccine
D)Because host cells have RNA in them, and thus don't raise antibodies against RNA
E)Because DNA genomes mutate less rapidly than RNA genomes
A)Because smallpox is an enveloped virus
B)Because viruses with DNA genomes must replicate inside a host cell
C)Because RNA is more stable than DNA, and is less likely to be destroyed by the vaccine
D)Because host cells have RNA in them, and thus don't raise antibodies against RNA
E)Because DNA genomes mutate less rapidly than RNA genomes
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54
figure 15.9 
It has been difficult to generate drugs to treat AIDS for which reason?
A)HIV does not cause AIDS
B)HIV does not use any enzymes that can be targeted by drugs
C)HIV mutates rapidly because reverse transcriptase lacks proofreading
D)The only way to kill a virus is with a vaccine, not with drugs
E)People with HIV infections die very rapidly, before the drugs have a chance to cure them

It has been difficult to generate drugs to treat AIDS for which reason?
A)HIV does not cause AIDS
B)HIV does not use any enzymes that can be targeted by drugs
C)HIV mutates rapidly because reverse transcriptase lacks proofreading
D)The only way to kill a virus is with a vaccine, not with drugs
E)People with HIV infections die very rapidly, before the drugs have a chance to cure them
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55
figure 15.9 
If a person is treated with a single anti-HIV drug,they often end up with a resistant strain.How does this occur?
A)The drugs weaken the immune system, making a patient more susceptible to infection with resistant strains of HIV
B)The drug causes mutations in the HIV, making them resistant to the drug
C)The drugs kill all sensitive viruses, leaving only the pre-existing resistant viruses
D)The HIV wants to avoid the drug, so it becomes resistant

If a person is treated with a single anti-HIV drug,they often end up with a resistant strain.How does this occur?
A)The drugs weaken the immune system, making a patient more susceptible to infection with resistant strains of HIV
B)The drug causes mutations in the HIV, making them resistant to the drug
C)The drugs kill all sensitive viruses, leaving only the pre-existing resistant viruses
D)The HIV wants to avoid the drug, so it becomes resistant
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56
figure 15.9 
Based on figure 15.9,which of the following statements is most likely accurate?
A)HIV arose more than once
B)HIV groups M, N, and O will be more similar to each other than to SIV
C)SIV only arose once
D)The SIV strains will all have more sequence similarity with each other than with any of the HIV groups
E)HIV and SIV are not genetically related

Based on figure 15.9,which of the following statements is most likely accurate?
A)HIV arose more than once
B)HIV groups M, N, and O will be more similar to each other than to SIV
C)SIV only arose once
D)The SIV strains will all have more sequence similarity with each other than with any of the HIV groups
E)HIV and SIV are not genetically related
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57
figure 15.4 
Reviewing figure 15.4,why could researchers use PCR to amplify viral DNA from the chimp Marilyn's tissues?
A)Because the HIV is converted to DNA and integrated into a cell's chromosome
B)Because PCR uses a reverse transcriptase and can thus detect RNA
C)Because HIV uses DNA as its genetic material
D)Because some of the HIV will be stuck to the outside of a cell
E)Because PCR can amplify any genetic material

Reviewing figure 15.4,why could researchers use PCR to amplify viral DNA from the chimp Marilyn's tissues?
A)Because the HIV is converted to DNA and integrated into a cell's chromosome
B)Because PCR uses a reverse transcriptase and can thus detect RNA
C)Because HIV uses DNA as its genetic material
D)Because some of the HIV will be stuck to the outside of a cell
E)Because PCR can amplify any genetic material
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58
Rhinovirus is an RNA virus that causes the common cold and sinus infections.The virus does not contain an envelope.What would you predict to be the primary route of transmission of rhinovirus?
A)Sexual contact
B)Blood
C)Aerosol
D)Insects
E)Parasites
A)Sexual contact
B)Blood
C)Aerosol
D)Insects
E)Parasites
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59
Most scientific evidence points to the HIV viruses originating in Africa.
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60
A vaccine against the influenza virus would result in production of antibodies against which of the following?
A)The protein coat
B)Viral RNA
C)Viral DNA
D)Proteins in the envelope
E)Lipids in the envelope
A)The protein coat
B)Viral RNA
C)Viral DNA
D)Proteins in the envelope
E)Lipids in the envelope
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