Deck 45: Antineoplastic Agents

Question 1

The overall effect of gonadotropin inhibitors for a patient with prostate cancer is to inhibit the production of:

A) Estrogen
B) Progesterone
C) Sperm
D) Testosterone

Answer 1

Testosterone

Question 2

Which two systems can cancer use to metastasize?

A) Digestive system and lymphatic system
B) Respiratory system and lymphatic system
C) Circulatory system and lymphatic system
D) Circulatory system and nervous system

Answer 2

Circulatory system and lymphatic system

Question 3

What common approach is used to treat cancer?

A) Surgery
B) Radiation
C) Chemotherapy
D) All of these are correct.

Answer 3

All of these are correct.

Question 4

What is the primary course of therapy used to treat diffuse tumors?

A) Dietary supplementation
B) Surgery
C) Radiation
D) Chemotherapy

Question 5

A leukemia patient is currently not responding to cyclophosphamide despite having favorable results with the medication in the past.Where might an additional problem be taking place?

A) Pancreas
B) Kidneys
C) Gallbladder
D) Liver

Question 6

Mr.Smith is not showing a positive response after receiving his chemotherapy.What would be the next step in his treatment?

A) Increase the dose of the current chemotherapy medication.
B) Change to a different chemotherapy medication in the same family.
C) Initiate combination therapy.
D) Change to a completely different chemotherapy medication.

Question 7

As cancer undergoes metastasis,the sites of new tumor development are called:

A) Origination sites
B) Primary sites
C) Secondary sites
D) Peripheral sites

Question 8

What type of alkylating drugs would be good for treating brain tumors?

A) Nitrosoureas
B) Nitrogen mustard
C) Platinum derivatives
D) Antimetabolites

Question 9

A medication that can be taken prophylactically by women who have a family history of developing breast cancer is:

A) Anastrozole
B) Tamoxifen
C) Leuprolide
D) Flutamide

Question 10

Mr.Smith was temporarily taken off chemotherapy despite responding very well to treatment.The reason for this would be that:

A) Additional time allows medical staff to test for remission.
B) Additional time will allow for recovery of the normal cells.
C) Additional time prevents the development of myelosuppression.
D) Additional time allows the immune system to fight off the tumor.

Question 11

This approach in cancer treatment will follow primary treatment in order to kill remaining cancer cells:

A) Dietary changes
B) Chemotherapy
C) Surgery
D) Radiation

Question 12

A patient experiences severe tissue damage after receiving an intravenous injection of a chemotherapy agent.This effect is a result of:

A) Overdose of kanamycin
B) Extravasation of doxorubicin
C) Compromised liver function
D) Problems with renal tubular reabsorption

Question 13

An advantage of raloxifene over the other hormone antagonists is:

A) Stimulation of uterine lining proliferation does not occur.
B) Cytotoxicity does not occur.
C) Vasomotor hot flashes are reduced.
D) Blood clotting factors are increased.

Question 14

Why would leucovorin need to be administered after methotrexate therapy?

A) To resume blood cell production
B) To reduce oxygen supply to cancer cells
C) To reestablish normal blood glucose levels
D) To reduce plasma cortisol levels

Question 15

Tumor growth inhibition by the vinca alkaloids occurs by:

A) Inhibition of transcription
B) Inhibition of protein translation
C) Metaphase arrest
D) Anaphase arrest

Question 16

Cancer can be broadly classified into these two categories:

A) Solid tumors and diffuse tumors
B) Solid tumors and vesicular tumors
C) Vesicular tumors and diffuse tumors
D) Lymphatic tumors and diffuse tumors

Question 17

Which of the following would best represent the best drug product of current research on developing a new chemotherapeutic medication?

A) Antimetabolite
B) Alkylating drug
C) Polyclonal antibody
D) Monoclonal antibody

Question 18

Mrs.Smith's treatment for cancer is showing promise.The results of her first treatment showed a 50% reduction of tumor cells.Why would only one more treatment not be enough to eradicate the cancer from her body?

A) The treatment eradicates cancer cells by percentage, not number.
B) The treatment eradicates cancer cells by number, not percentage.
C) Additional treatments will serve as a precautionary measure.
D) The treatment is complete, and additional treatment will not be necessary.

Question 19

Methotrexate is a chemotherapeutic medication that:

A) Causes metaphase arrest
B) Blocks DNA synthesis
C) Inhibits transcription
D) Inhibits protein translation

Question 20

A 25-year-old female chemotherapy patient might also be taking which type of medication in addition to her chemotherapy regimen?

A) Estrogen replacement therapy
B) Progesterone replacement therapy
C) Oral contraceptives
D) Follicle-stimulating hormone