Deck 39: Pancreatic Hormones and Antidiabetic Drugs

Question 1

Cells that secrete GIP and GLP-1,which promote insulin secretion,are located in the:

A) Small intestines
B) Large intestines
C) Pancreas
D) Liver

Answer 1

Small intestines

Question 2

In gestational diabetes,hormones produced in the ??_____ will cause insulin resistance.

A) Placenta
B) Ovaries
C) Uterus
D) Pituitary gland

Answer 2

Placenta

Question 3

Hyperglycemia in diabetes mellitus is a direct result of:

A) GLUT1 transporter proteins not being able to form a glucose channel
B) GLUT2 transporter proteins not being able to migrate to the plasma membrane
C) GLUT3 transporter proteins not being able to form a glucose channel
D) GLUT4 transporter proteins not being able to migrate to the plasma membrane

Answer 3

GLUT4 transporter proteins not being able to migrate to the plasma membrane

Question 4

The autoimmune response associated with type 1 diabetes in which beta cells are destroyed is thought to be initiated by:

A) Obesity
B) A Coxsackie virus
C) A staphylococcal infection
D) The aging process

Question 5

Which glucose receptor also functions as a carrier channel in cells?

A) GLUT1
B) GLUT2
C) GLUT3
D) GLUT4

Question 6

Which antidiabetic agents are considered hypoglycemics?

A) Insulins and alpha-glucosidase inhibitors
B) Biguanides and secretagogues
C) Insulin sensitizers and peptidase inhibitors
D) Insulins and secretagogues

Question 7

Which one of the following receptors is not coupled to a G-protein?

A) GIP receptor
B) GLP-1 receptor
C) Glucagon receptor
D) Insulin receptor

Question 8

Medical professionals can determine how well a patient is monitoring his or her blood glucose levels by:

A) Analyzing blood glucose levels
B) Analyzing a urine sample
C) Analyzing red blood cells
D) Analyzing white blood cells

Question 9

Phase 2 insulin secretion will occur when:

A) High glucose levels persist after 20 minutes from eating
B) Low glucose levels persist after 20 minutes from eating
C) High glucose levels persist after 2 hours from eating
D) Low glucose levels persist after 2 hours from eating

Question 10

A major factor in the development of type 2 diabetes mellitus is:

A) Genetics
B) Insulin resistance
C) Obesity
D) Age

Question 11

The need for amputation for diabetics occurs because of:

A) An increase in levels of stored glucose in the extremities
B) A decrease in immune response with high levels of insulin
C) A decrease in immune response with high levels of glucagon
D) Inadequate circulation to the extremities

Question 12

Insulin will cause a majority of the blood glucose to be taken up in:

A) The liver
B) Smooth muscle
C) Skeletal muscle
D) Cardiac muscle

Question 13

Glucagon is secreted:

A) When GIP and GLP-1 are released
B) When blood glucose levels are above normal
C) When blood glucose levels are below normal
D) After consuming a large meal

Question 14

Diabetes mellitus is a syndrome that usually involves a problem with which hormone?

A) Insulin
B) Glucagon
C) Amylin
D) GIP

Question 15

What will be the effect on urine output for patients with diabetes mellitus?

A) Urine output will increase due to a lack of antidiuretic hormone being produced.
B) Urine output will decrease due to osmotic pressure of excess glucose in blood.
C) Urine output will increase due to excess glucose being filtered into the renal tubule.
D) Urine output will decrease due to increased production of antidiuretic hormone.

Question 16

Excess amounts of insulin in the blood will have what effect on the number of insulin receptors present?

A) Slight increase in the number of insulin receptors present
B) Decrease in the number of insulin receptors present
C) No change in the number of insulin receptors present
D) Dramatic increase in the number of insulin receptors present

Question 17

Metabolic acidosis in diabetics will occur as a result of:

A) The breakdown of carbohydrates
B) The breakdown of fats
C) The breakdown of proteins
D) The breakdown of nucleic acids

Question 18

What ion channel is essential for the release of insulin and amylin into the blood?

A) Sodium
B) Calcium
C) Potassium
D) Chloride

Question 19

What endocrine response occurs after a healthy person ingests a meal?

A) Glycogenolysis is increased.
B) Incretin secretion is reduced.
C) Stored glucagon is immediately released.
D) Stored insulin is immediately released.

Question 20

Once potassium channels are closed from the production of ATP in the beta cell,what is needed for the release of insulin?

A) Depolarization caused by sodium influx
B) Repolarization caused by potassium efflux
C) Depolarization caused by calcium influx
D) Hyperpolarization caused by potassium efflux