Deck 33: Therapy of Gastrointestinal Disorders: Peptic Ulcers, gerd, and Vom

Question 1

Which medications can actually promote the formation of ulcers by interfering with mucus production or secretion?

A) NSAIDs and diuretics
B) NSAIDs and steroids
C) Steroids and diuretics
D) Steroids and antibiotics

Answer 1

NSAIDs and steroids

Question 2

Acid secretion and gastrin-induced secretion is inhibited by blocking which receptors?

A) Cholinergic and H1 receptors
B) Adrenergic and H1 receptors
C) Cholinergic and H2 receptors
D) Adrenergic and H2 receptors

Answer 2

Cholinergic and H2 receptors

Question 3

When taking oral H2 receptor antagonists,it is important to remember that

A) The medication will interact with citrus juices
B) The medication could interact with certain cardiovascular medications
C) The medication must be taken on an empty stomach
D) The medication can be taken with food

Answer 3

The medication can be taken with food

Question 4

Which H2 inhibitor should not be prescribed for a patient already taking calcium channel blockers,metoprolol,and phenytoin?

A) Cimetidine
B) Famotidine
C) Nizatidine
D) Ranitidine

Question 5

One common problem with long term use of antacids would be

A) Metabolic alkalosis
B) High magnesium content
C) High aluminum content
D) High sodium content

Question 6

One way to treat a patient with severe GERD would be to

A) Administer tissue grafting to replace eroded tissue
B) Remove damaged tissue through surgery
C) Administer triple therapy
D) Administer quadruple therapy

Question 7

Symptoms of chronic erosion of mucosal lining and perforation would include

A) Hyperglycemia
B) High levels of IgE antibodies
C) Hypertension
D) Presence of blood in stool or vomit

Question 8

A patient with liver problems should avoid which H2 receptor antagonist medications?

A) Ranitidine and famotidine
B) Ranitidine and cimetidine
C) Nizatidine and cimetidine
D) Nizatidine and ranitidine

Question 9

Gastric juices are released during the gastric phase from

A) Gastrin and secretin
B) Gastrin and cholecystokinin
C) Sensory and mental input
D) Distention of the stomach when food enters

Question 10

Gastric juices mainly consist of

A) HCl and gastrin
B) HCl and pepsin
C) Sodium bicarbonate and gastrin
D) Sodium bicarbonate and pepsin

Question 11

The mechanism of action of Sucralfate has it classified as

A) An antacid
B) A prostaglandin
C) An anticholinergic
D) None of these are correct

Question 12

One way to directly block the secretion of acid and pepsin in the stomach would be to

A) Administer an H1 blocker
B) Administer a proton pump inhibitor
C) Administer an H2 blocker
D) Administer an anticholinergic

Question 13

What are two types of receptor antagonists that are used as antiemetics?

A) Serotonin 5-HT3 and NK-1
B) Serotonin 5-HT2 and NK-1
C) Serotonin 5-HT3 and NK-2
D) Serotonin 5-HT2 and NK-2

Question 14

To completely stop acid secretion between meals would put a person at increased risk of

A) Metabolic acidosis
B) Metabolic alkalosis
C) GI infections
D) Constipation

Question 15

Omeprazole works by

A) Inhibiting a hydrogen-potassium pump in mucosal cells
B) Inhibiting a sodium-potassium pump in mucosal cells
C) Inhibiting a hydrogen-potassium pump in parietal cells
D) Inhibiting a sodium-potassium pump in parietal cells

Question 16

Why should cimetidine never be mixed with a barbiturate when compounding an IV admixture?

A) Both drugs will exhibit pharmacological antagonism with each other
B) Cimetidine will precipitate out of solution
C) Both drugs will exhibit pharmacological synergism with each other
D) The barbiturate will precipitate out of solution

Question 17

Antibiotic treatment for peptic ulcers caused by H.pylori require the use of

A) Two antibiotics
B) One antibiotic and one antifungal
C) Three antibiotics
D) One antibiotic and one antiprotozoal

Question 18

Which of the following is not a common cause of peptic ulcers?

A) Overproduction of inhibitory enzyme to stop acid secretion
B) A bacterium called Helicobacter pylori (H. pylori)
C) Excess gastric acid secretion
D) Insufficient production of protective mucus

Question 19

In treating an H.pylori peptic ulcer,triple therapy refers to using

A) Two antibiotics and a bismuth compound
B) Two antibiotics and a proton pump inhibitor
C) An antibiotic, a bismuth compound, and a proton pump inhibitor
D) An antibiotic, an antifungal, and a bismuth compound

Question 20

Receptors found on parietal cells that increase secretion of HCl when activated

A) Cholinergic
B) Prostaglandin
C) Histamine
D) Adrenergic