Deck 24: Antianginal Drugs

Question 1

Compare the routes of administration of the nitrates and determine the most common route of administration during attacks of angina.

A) Topical
B) Intravenous
C) Sublingual
D) Oral

Answer 1

Sublingual

Question 2

Use the adverse-effect profile of the nitrates to determine which of the following is not an adverse effect of this drug class.

A) Bradycardia
B) Cutaneous flushing
C) Fainting
D) Headache

Answer 2

Bradycardia

Question 3

Distinguish between the adverse effects of the beta-adrenergic blockers and those of the calcium channel blockers,and select the statement that does not correspond with an adverse effect that would result from an overdosage of the calcium channel blocker verapamil.

A) Bradycardia
B) Decreased myocardial contraction
C) Increased myocardial contraction
D) AV block

Answer 3

Increased myocardial contraction

Question 4

Differentiate between the classes of drugs available to treat angina,and select the drug that can be used in combination with the nitrates for patients who require more than one drug to control angina.

A) Calcium channel blockers
B) Beta-adrenergic blockers
C) Alpha-blockers
D) Angiotensin-converting enzyme inhibitors

Question 5

Alice is experiencing periods of angina,and she places a sublingual nitroglycerin tablet under her tongue as directed by her physician.After 5 minutes have passed,she is not feeling any relief.What step should be implemented next?

A) Seek medical assistance immediately.
B) Place another sublingual nitroglycerin tablet under her tongue.
C) Swallow the nitroglycerin tablet in order to get better absorption.
D) None of these are correct.

Question 6

The type of angina that is characterized by vasospasm is classified as:

A) Stable angina
B) Prinzmetal angina
C) Ischemia
D) Exertional angina

Question 7

Identify the term used for the reduction in blood flow caused by atherosclerosis.

A) Stable angina
B) Variant angina
C) Ischemia
D) Exertional angina

Question 8

Select the mechanism of action of the calcium channel blockers in the treatment of angina and CAD.

A) Prevention of influx of calcium ions into vascular smooth muscle
B) Reversal of the effects of sympathetic activation
C) Relaxation of vascular smooth muscle
D) All of these are correct.

Question 9

Differentiate between onset of action and duration of action,and select the correct duration of action of nitroglycerin ointment.

A) 30 minutes to 1 hour
B) 1 to 1.5 hours
C) 2 to 4 hours
D) 4 to 8 hours

Question 10

Identify the term used to describe the fatty degeneration of the coronary arteries.

A) Angina pectoris
B) Atherosclerosis
C) Ischemia
D) Hypercholesterolemia

Question 11

Samuel has been prescribed sublingual nitroglycerin for angina pain.You use the Physicians' Desk Reference and determine that the correct length of time that Samuel can expect to wait for the nitroglycerin's actions to take effect will be:

A) 1 to 3 minutes
B) 3 to 5 minutes
C) 5 to 7 minutes
D) 2 to 4 minutes

Question 12

Distinguish between the available dosage forms and strengths of nitrogylcerin,and select the available strengths of the sublingual nitroglycerin tablet Nitrostat.

A) 2.5-, 5-, and10-mg sublingual tablets
B) 0.3-, 0.4-, and 0.6-mg sublingual tablets
C) 40-mg CR tablets and capsules
D) 1-, 2-, and 3-mg extended-release buccal tablets

Question 13

Using the available treatment options for Prinzmetal angina,determine the preferred drug class for the treatment of variant or Prinzmetal angina.

A) Calcium channel blockers
B) Beta-adrenergic blockers
C) Alpha blockers
D) Angiotensin-converting enzyme inhibitors

Question 14

Describe the goal of the treatment of coronary artery disease.

A) Reducing the number and severity of anginal attacks
B) Limiting the progression of atherosclerosis
C) Preventing myocardial infarction
D) All of these are correct

Question 15

Use critical thinking to determine the correct nitrate drug that is used prophylactically to prevent the occurrence of anginal attacks.

A) Isosorbide dinitrate
B) Nitroglycerin for IV infusion
C) Sublingual nitroglycerin
D) Nitroglycerin extended-release capsules

Question 16

Differentiate between the pharmacologic and nonpharmacologic treatments for angina,and select the nonpharmacologic treatment that the patient should consider to prevent the progression of angina attacks.

A) Low-fat diet and exercise
B) Smoking cessation
C) Weight control
D) All of these are correct.

Question 17

Describe the type of information that should be given to a newly diagnosed angina patient about nitroglycerin.

A) Carry the prescribed medication at all times.
B) The tablets lose potency if exposed to air or light.
C) Discard unused nitroglycerin tablets that are more than 6 months old.
D) All of these are correct.

Question 18

Jason has been diagnosed by his physician with CAD and angina.He has been prescribed nitroglycerin for the angina.Select the drug that the physician can prescribe to treat Jason's CAD?

A) Nadolol
B) Propranolol
C) Atenolol
D) All of these are correct.

Question 19

Using the adverse-effects profile of the calcium channel blockers,determine the most common adverse effect associated with the use of the calcium antagonist agents.

A) Dizziness
B) Hypotension
C) Nausea and vomiting
D) GI distress

Question 20

Differentiate between the commercially available nitrate products,and determine the nitrate drug most commonly used to treat angina and coronary artery disease.

A) Isosorbide dinitrate
B) Isosorbide monohydrate
C) Nitroglycerin
D) All of these are correct.