Deck 1: Pharmacology: An Introduction

Question 1

The nonproprietary name of a medication is also known as the:

A) Trade name
B) Generic name
C) Chemical name
D) None of these are correct.

Answer 1

Generic name

Question 2

A medication administered intravenously will have a quicker _____ than a medication administered orally.

A) duration of action
B) onset of action
C) dosage form
D) route of administration

Answer 2

onset of action

Question 3

Toxic effects that are most often fatal occur from:

A) Low doses
B) Therapeutic doses taken PRN
C) High doses
D) Therapeutic doses taken on schedule

Answer 3

High doses

Question 4

What action follows after insulin binds to a receptor?

A) A series of changes will occur inside the cell.
B) The drug is immediately transformed into a metabolite.
C) Changes to the cell's membrane potential will stop all conduction.
D) The drug will signal additional drug molecules to the area.

Question 5

When epinephrine is administered to stimulate heart rate,the medication is acting as a(n)

A) Antagonist
B) Partial agonist
C) Agonist
D) Partial antagonist

Question 6

In a graded dose-response curve,one would expect a more potent medication to cause the curve to shift in what direction?

A)Up
B)Down
C)Left
D)Right

Question 7

Competitive antagonism occurs when:

A) Two agonists compete for the same receptor.
B) An agonist and an antagonist compete for the same receptor.
C) An antagonist directly inactivates an agonist.
D) An antagonist cancels out the effect of an agonist by binding to a unique receptor.

Question 8

Which of the following would not be considered a dose-dependent adverse effect?

A) Teratogen
B) Carcinogen
C) Kidney damage
D) Idiosyncrasy

Question 9

Drug potencies are compared using what value on a dose-response curve?

A) Therapeutic index
B) Half-life
C) ED50
D) LD50

Question 10

The therapeutic index of a drug is determined by comparing the _____ to the _____ in order to predict drug safety.

A) half-life; LD50
B) ED50; LD50
C) LD50; half-life
D) LD50; ED50

Question 11

Examples of common adverse effects would include all of these except:

A) Persistent diarrhea
B) Vomiting
C) Confusion
D) Anaphylaxis

Question 12

Three medications have the following therapeutic index values: 2,4,and 0.5.Which medication is the safest?

A) 0.5
B) 2
C) 4
D) None of these are safe to use.

Question 13

What type of curve should be used for representing data when a proper dosing frequency is being determined?

A) Time-response curve
B) Scatter plot
C) Graded dose-response curve
D) Quantal dose-response curve

Question 14

Mrs.Breaux almost became comatose after receiving an overdose of morphine while in the hospital.In order to reverse this effect,the doctor ordered naloxone,which served as a(n)

A) Partial antagonist
B) Agonist
C) Partial agonist
D) Antagonist

Question 15

The main source of new drugs derived today is:

A) Synthetic sources
B) Animal sources
C) Plant sources
D) Mineral sources

Question 16

Which of the following would not be considered an adverse effect from taking an oral antibiotic?

A) Extravasation
B) Diarrhea
C) Nausea
D) Vomiting

Question 17

The phenomenon that occurs upon taking additional doses of acetaminophen for pain when a 100 percent response has been attained is called

A) Ceiling effect
B) Tolerance
C) First-pass effect
D) Purkinje effect

Question 18

Taking two aspirin tablets instead of one will always result in:

A) Two times the analgesic effect
B) An enhanced analgesic effect
C) No change in analgesic effect
D) Toxicity

Question 19

In toxicity testing,animals are injected with a particular dose of medication so that an LD50 value can be determined.The best curve to represent the findings would be a:

A) Time-response curve
B) Scatter plot
C) Graded dose-response curve
D) Quantal dose-response curve

Question 20

The most current drug reference source would be:

A) Physicians' Desk Reference
B) Drug Facts and Comparisons
C) United States Pharmacopeia/National Formulary
D) Merck Index