Deck 19: Reconstitution of Solutions

Question 1

Directions: Use the label (where provided) to obtain the necessary information. Round answers to the nearest tenth where indicated.
Order: cefazolin (Ancef) 0.375 g IM q6h
Available:
a. How many milliliters of diluent will you add for IM use? _____ mL
b. Why will the reconstituted volume be larger than the amount of diluent? _____
c. What is the dosage strength of the reconstituted solution? ___________
d. What are the directions for use?
e. How many milliliters will you administer? _____ mL

Answer 1

a. 2.5
b. The medication itself adds volume
c. 330 mg per mL
d. For IM or IV use
e. 1.1

Question 2

Directions: Prepare the following strength solutions. Describe your calculations.
800 mL of 3/4 strength Sustacal via gastrostomy over 6 hours

Answer 2

3/4 * 800 = 600 mL of formula (solute)
Amount of solution (800 mL) - Amount of solute (600 mL) = Amount needed to dissolve (200 mL)
Therefore, you will add 200 mL of water to 600 mL of Sustacal to make 800 mL of 3/4 strength Sustacal.

Question 3

Directions: Use the label (where provided) to obtain the necessary information. Round answers to the nearest tenth where indicated.
Order: Amoxicillin clavulanate potassium 275 mg p.o. q12h
Available:
a. How much diluent is recommended for reconstitution? _________
b. What is the dosage strength of amoxicillin when reconstituted? _______
c. What is the total volume of the reconstituted solution? __________
d. How many milliliters will you administer? (based on the amoxicillin) ________

Answer 3

a. 87 mL
b. 400 mg per 5 mL
c. 100 mL
d. 3.4 mL

Question 4

Directions: Prepare the following strength solutions. Describe your calculations.
Prepare irrigant 250 mL 1/2 strength solution: ______________________________

Question 5

Directions: Prepare the following strength solutions. Describe your calculations.
a. What is the total dosage strength of the vial? _____
b. If 450,000 units IV of penicillin were ordered, which concentration would be appropriate to mix? _____
c. How much diluent must be added to make the appropriate concentration? _____
d. If the medication is reconstituted at 1:00 AM on December 18, what must you print on the label? _______________
e. How many milliliters will you give to administer 450,000 units IV? _______

Question 6

Order: Doxycycline 100 mg IVPB q12h
Available: How many milliliters will you administer? __________

Question 7

Directions: Use the label (where provided) to obtain the necessary information. Round answers to the nearest tenth where indicated.
Order: Vancomycin 0.85 g IV q12h
Available:
a. How many milliliters of diluent are used to reconstitute the solution? _____ mL
b. What is the dosage strength of the prepared solution? _______________
c. How many milliliters will you add to the IV? _____ mL

Question 8

Directions: Use the label (where provided) to obtain the necessary information. Round answers to the nearest tenth where indicated.
Order: Synagis 65 mg IM q8h
Available: Refer to label and package insert.
a. What diluent is recommended for reconstitution? ___________
b. How much diluent must be added? ____________
c. What is the dosage strength of the reconstituted solution? ______
d. How many milliliters will you administer? ________
e. How long is the reconstituted solution good for? ___________

Question 9

Directions: Indicate how you would prepare each of the following using full-strength hydrogen peroxide (solute) and normal saline (solvent).
0.24 L of 1/3 strength for wound care

Question 10

Directions: Indicate how you would prepare each of the following using full-strength hydrogen peroxide (solute) and normal saline (solvent).
300 mL of 3/4 strength for skeletal pin care

Question 11

Order: Zithromax 250 mg p.o. daily
Available:
a. How many milliliters of diluent must be added to the bottle? _____________
b. What is the final concentration of the prepared solution? ________________
c. How many milliliters will you administer? ___________________

Question 12

Directions: Prepare the following strength solutions. Describe your calculations.
Order: Amoxicillin 175 mg p.o. q8h
Available:
a. Form: _______________
b. Route of administration: _______________
c. Type of diluent and amount to use: _______________
d. Directions for mixing: _______________
e. Dosage strength of reconstituted solution: _____
g. How many milliliters will you administer? __________

Question 13

Directions: Prepare the following strength solutions. Describe your calculations.
360 mL of 1/4 strength Ensure percutaneous endoscopic (PEG) tube over 4 hours

Question 14

Directions: Prepare the following strength solutions. Describe your calculations.
1/4 strength Ensure 8 oz p.o. q4h for 24 hours

Question 15

Directions: Indicate how you would prepare each of the following using full-strength hydrogen peroxide (solute) and normal saline (solvent).
8 oz of 1/2 strength for wound care

Question 16

Directions: Use the label (where provided) to obtain the necessary information. Round answers to the nearest tenth where indicated.
Order: Ceftriaxone 0.5 g IV q12h
Available:
a. How many milliliters of diluent will you add to reconstitute the solution for IV use? _____ mL
b. What is the dosage strength of the reconstituted solution for IV use? _____
c. How many milliliters will you administer? __________ mL

Question 17

Directions: Use the label (where provided) to obtain the necessary information. Round answers to the nearest tenth where indicated.
Order: Zosyn 3 g IV q6h
Available:
a. How many milliliters of diluent should be used to reconstitute the solution? _____ mL
b. What is the dosage strength of the prepared solution? _______________
c. How many milliliters will you add to the IV? _____ mL