Deck 15: Drugs for Treating Schizophrenia and Mood Disorders

Question 1

Those exposed to long-term treatment with antipsychotic drugs have a 15 to 20 percent risk of developing tardive dyskinesia.

Answer 1

True

Question 2

There is a low risk that large doses of antipsychotic drugs will lead to overdose.

Answer 2

True

Question 3

Clozaril is a second-generation (atypical)antipsychotic drug.

Answer 3

True

Question 4

All schizophrenic patients must take continual doses (maintenance)of medication indefinitely.

Question 5

Depression is a mood disorder.

Question 6

Beginning in the mid-1950s,many schizophrenic patients began to be treated on an outpatient basis.

Question 7

Tardive dyskinesia often appears in the behavior of medicated schizophrenics within a day or so.

Question 8

Another name for psychiatric drugs is psychotropic medication.

Question 9

The incidence of Parkinson's-like symptoms as a side effect of typical antipsychotic drugs implies a dopamine connection in schizophrenia.

Question 10

Schizophrenia is more common in men than women.

Question 11

Abilify is a "third-generation" antipsychotic drug.

Question 12

The concordance rate for schizophrenia is higher in identical twins than it is in fraternal twins.

Question 13

Chlorpromazine (brand name: Thorazine)is an example of a typical antipsychotic drug.

Question 14

Antipsychotic drugs have a high potential for abuse.

Question 15

Treatment using medications such as Clozaril is generally expensive due to the required monitoring of blood.

Question 16

While first-generation antipsychotic drugs are effective in treating delusional behavior,they are less effective in treating social withdrawal.

Question 17

Generally speaking,men and younger patients show a higher incidence of tardive dyskinesia.

Question 18

Weight gain is a side effect of Zyprexa,but not of Risperdal.

Question 19

Risperidone (brand name: Risperdal)unfortunately increases the risk of a potentially lethal blood disorder called agranulocytosis.

Question 20

Schizophrenic patients frequently have multiple or split personalities.

Question 21

First-generation antidepressants include MAO inhibitors.

Question 22

Serotonin-specific reuptake inhibitors (SSRIs)are known actually to be MAO-inhibitors,now that we know the neurotransmitter involved.

Question 23

Prozac carries a high risk for both physical dependence and psychological dependence.

Question 24

Drugs that are weak blockers of dopamine are most effective in treating schizophrenia.

Question 25

After a deep period of depression,the likelihood of a suicide attempt is increased during the initial phase of an upswing in mood.

Question 26

Paxil was the first available SSRI for the treatment of depression.

Question 27

MAO inhibitors inhibit MAO in the brain only;MAO elsewhere in the body is unaffected.

Question 28

Third-generation antidepressant drugs act upon both serotonin and norepinephrine in the brain.

Question 29

President Abraham Lincoln suffered severe depression throughout his presidency.

Question 30

Patients being treated for cardiovascular disorders should avoid taking Prozac.

Question 31

Patients under treatment with fluoxetine (brand name: Prozac)run an increased risk of seizures.

Question 32

Tricyclic antidepressants work in the brain by inhibiting monoamine oxidase (MAO).

Question 33

Schizophrenia is considered to be related to a low level of dopamine activity in the brain.

Question 34

Clozapine (brand name: Clozaril)is believed to act in the same way as chlorpromazine (brand name: Thorazine)in the brain.

Question 35

Prozac increases the risk of suicide.

Question 36

Fluoxetine (brand name: Prozac)is an example of an antidepressant drug that works in the brain by reducing the activity level of norepinephrine.

Question 37

Treatment with MAO inhibitors for depression is risky unless the diet is carefully monitored and restricted.

Question 38

An inclination toward depression increases the risk of an attempted suicide.

Question 39

Third-generation antipsychotic drugs do nothing but block D₂ receptors.

Question 40

Taking too much L-dopa (anti-Parkinson's drug)can result in symptoms of schizophrenia in Parkinson's patients.

Question 41

MAO molecules stimulate dopamine,norepinephrine,and serotonin at the synapse where they operate.

Question 42

Deinstitutionalization was greatly accelerated by the expansion of Medicare and Medicaid programs.

Question 43

Lithium carbonate has potential toxic effects to the thyroid gland and kidneys.

Question 44

Antipsychotic drugs generally refer to drugs used to treat __________.

A)mental illness in general
B)schizophrenia
C)depression
D)depression and extreme anxiety

Question 45

Second-generation antipsychotic drugs for the treatment of bipolar should not be administered to elderly patients with dementia,on the basis of evidence showing an elevated risk of death from cardiovascular disease or infections such as pneumonia.

Question 46

Lithium carbonate has been a major drug for the treatment of bipolar disorder.

Question 47

If there is a strong genetic component to schizophrenia in families,the concordance for identical twins should be __________.

A)higher than the concordance for fraternal twins
B)lower than the concordance for fraternal twins
C)equivalent to the concordance for fraternal twins
D)about 50 percent

Question 48

The biomedical model assumes that __________.

A)schizophrenia is different from mood disorders
B)psychiatrists are not the appropriate professionals to supervise psychotropic medication
C)schizophrenia can be successfully treated
D)mental illness is a result of biochemical processes in the brain

Question 49

Tricyclic antidepressant drugs act on enzymes in the synapse.

Question 50

One indication that the biomedical model is an appropriate perspective on mental illness is the following observation: __________.

A)the concordance rate for schizophrenia among pairs of identical twins is relatively low
B)the incidence of schizophrenia around the world is remarkably stable
C)psychiatric drugs have significant side effects
D)all of the above

Question 51

According to the text,the number of patients with severe mental illness who are in prison is a major social concern.

Question 52

An individual who has a split personality or multiple personalities is diagnosed as having __________.

A)depression
B)schizophrenia
C)a dissociative disorder
D)none of the above

Question 53

Which statement is true?

A)Swedes and Eskimos show an equivalent incidence of schizophrenia in their populations,but African tribal people show a lower incidence.
B)Swedes and African tribal people show an equivalent incidence of schizophrenia in their populations,but Eskimos show a higher one.
C)Swedes,Eskimos,and African tribal people all show an equivalent incidence of schizophrenia in their populations.
D)Swedes,Eskimos,and African tribal people do not have any diagnosed schizophrenia in their populations.

Question 54

Some second-generation antipsychotic drugs have been shown to be useful in treating bipolar disorder.

Question 55

It may be possible that depression is expressed in different neurochemical ways in different people.

Question 56

Since the late 1960s,the severely mentally ill have been mostly treated through large-scale institutionalization.

Question 57

Off-label usage is an illegal practice.

Question 58

The biomedical model takes into consideration __________.

A)adverse sociological factors
B)psychodynamic factors
C)cognitive factors
D)none of the above

Question 59

The overall risk of suicide among children and adolescents taking SSRI antidepressants is low.

Question 60

There are indications that the third-generation antipsychotic drug Abilify might be helpful in controlling aggressive behavior in the autistic population.

Question 61

Some schizophrenics experience __________.

A)multiple personalities
B)dissociative disorders
C)feelings of paranoia
D)visual hallucinations

Question 62

With antipsychotic medication,agitated patients become more _______ and withdrawn patients become more _______.

A)relaxed;withdrawn
B)agitated;sociable
C)relaxed;sociable
D)agitated;withdrawn

Question 63

Schizophrenia __________.

A)affects more women than men
B)affects more men than women
C)appears at a younger age in men than women
D)appears at a younger age in woman than men

Question 64

If you lived in a small town with a population of 3000,how many individuals in this population would be expected by chance alone to be schizophrenic?

A)1 or 2
B)about 3
C)about 10
D)about 30

Question 65

In 1955,about _______ of all admitted hospital patients were there for psychiatric reasons.

A)20 percent
B)35 percent
C)50 percent
D)75 percent

Question 66

Thorazine,Haldol,Navane,and Mellaril are all examples of __________.

A)typical antidepressants
B)typical antipsychotic drugs
C)atypical antidepressants
D)atypical antipsychotic drugs

Question 67

The most appropriate way of viewing a schizophrenic patient is to understand him or her as having __________.

A)a split mind
B)a depressed mind
C)a split-off mind
D)a strange mind

Question 68

Antipsychotic drugs have a low potential for abuse since they do not produce __________.

A)tolerance
B)euphoria
C)craving or psychological dependence
D)all of the above

Question 69

The peak in the number of hospitalized psychiatric patients in the United States was reached around __________.

A)1905
B)1938
C)1955
D)1982

Question 70

A belief that is clearly not rooted in reality is referred to as a(n)__________.

A)delusion
B)hallucination
C)alliteration
D)illusion

Question 71

The resident population in U.S. mental hospitals decreased by 80 percent as a result of __________.

A)the introduction of antipsychotic drugs
B)neurosurgical interventions
C)deinstitutionalization
D)both A and C

Question 72

Deinstitutionalization __________.

A)refers to a policy of limited hospitalizations of mental patients
B)has resulted in an increase in the number of hospitalized schizophrenic patients
C)has helped to cure countless numbers of schizophrenic patients
D)all of the above

Question 73

What is true about the typical antipsychotic drugs?

A)They are not very effective in reducing apathy.
B)They are effective in treating social consciousness disorder.
C)They are not very effective in reducing delusional behavior.
D)They do not have serious side effects.

Question 74

Prior to the mid-1950s,the principal option for treating schizophrenia was __________.

A)to administer drugs like Thorazine or Haldol
B)to administer CNS stimulants like cocaine
C)to sedate sufferers with drugs like barbiturates
D)to allow schizophrenics to heal themselves

Question 75

According to the text,side effects of first-generation antipsychotic drugs include all but which of the following?

A)over-sensitization of the skin
B)extreme nausea and dehydration
C)blurred vision
D)weight gain

Question 76

Large doses of antipsychotic drugs __________.

A)produce euphoria
B)have high potential for psychological dependence
C)impair breathing
D)do not produce tolerance

Question 77

Schizophrenic hallucinations are most frequently __________.

A)auditory
B)visual
C)a synesthesia-type blend of auditory and visual sensations
D)somatosensory

Question 78

Catatonia refers to __________.

A)a jerky movement of the lower limbs
B)a trance-like state in which the body remains immobile
C)a set of delusions characteristic of schizophrenia
D)a profound level of mental depression despite normal body movement

Question 79

In most cases,schizophrenic patients take their medication __________.

A)orally
B)intravenously
C)intramuscularly
D)sublingually

Question 80

Mercury poisoning can lead to __________.

A)fatigue
B)anxiety
C)dementia
D)all of the above