Deck 8: Psychedelic Drugs

Question 1

Atropa belladonna is the scientific name for:

A)Jamestown weed.
B)mandrake.
C)moonflower.
D)deadly nightshade.

Answer 1

D

Question 2

Phencyclidine affects _____,whereas psilocybin affects _____.

A)acetylcholine; opioid
B)opioid; acetylcholine
C)glutamate; serotonin
D)serotonin; glutamate

Answer 2

C

Question 3

Ketamine (Ketalar)affects the neurotransmitter:

A)serotonin.
B)glutamate.
C)dopamine.
D)acetylcholine.

Answer 3

B

Question 4

Scopolamine affects _____,and LSD (lysergic acid diethylamide)affects _____.

A)acetylcholine; serotonin
B)serotonin; acetylcholine
C)dopamine; glutamate
D)glutamate; dopamine

Question 5

Scopolamine is _____ to _____.

A)agonist; acetylcholine
B)agonist; serotonin
C)antagonist; acetylcholine
D)antagonist; serotonin

Question 6

The term psychotomimetic refers to the activation of:

A)the sympathetic nervous system.
B)the parasympathetic nervous system.
C)psychotic states.
D)hallucinations.

Question 7

DMT affects the neurotransmitter:

A)serotonin.
B)norepinephrine.
C)dopamine.
D)acetylcholine.

Question 8

Scopalamine is found in all of the following plants EXCEPT:

A)Datura inoxia.
B)Datura stramonium.
C)Lophophora williamsii.
D)Mandragora officinarum.

Question 9

Acetylcholinesterase (AchE)acts by:

A)blocking acetylcholine receptors.
B)activating acetylcholine receptors.
C)metabolizing acetylcholine.
D)synthesizing acetylcholine.

Question 10

Salvinorin A is _____ to _____.

A)agonist; opioid
B)agonist; serotonin
C)antagonist; opioid
D)antagonist; serotonin

Question 11

All of the following are effects of scopolamine EXCEPT:

A)dry skin.
B)dry mouth.
C)decreased body temperature.
D)fatigue.

Question 12

A psychonaut is a person who uses:

A)psychedelic drugs.
B)cocaine.
C)amphetamines.
D)methamphetamines.

Question 13

Scopalamine is an _____ to the _____ receptor.

A)agonist; nicotinic
B)agonist; muscarinic
C)antagonist; nicotinic
D)antagonist; muscarinic

Question 14

All of the following are effects of Scopalamine EXCEPT:

A)sweating.
B)increased body temperature.
C)blurred vision.
D)amnesia.

Question 15

______ is considered the prototypical anticholinergic drug possessing psychedelic properties.

A)Atropine
B)L-hyoscyamine
C)Scopolamine
D)Mescaline

Question 16

Physostigmine acts by:

A)blocking acetylcholine receptors.
B)activating acetylcholine receptors.
C)blocking acetylcholinesterase (AchE).
D)activating acetylcholinesterase (AchE).

Question 17

Monoaminergic psychedelics resemble:

A)dopamine.
B)GABA.
C)glutamate.
D)opioid.

Question 18

Acetylcholinesterase (AchE)_____ acetylcholine (Ach)in the _____.

A)metabolizes; synaptic cleft
B)metabolizes; presynaptic terminal
C)synthesizes; synaptic cleft
D)synthesizes; presynaptic terminal

Question 19

Monoaminergic psychedelics resemble all of the following EXCEPT:

A)dopamine.
B)serotonin.
C)norepinephrine.
D)acetylcholine.

Question 20

Salvinorin A is a(n):

A)cholinergic antagonist.
B)serotonin agonist.
C)glutamatergic NMDA antagonist.
D)opioid kappa agonist.

Question 21

__________ is related to the hormones prolactin and oxytocin.

A)Emotion
B)Memory
C)Depression
D)Empathy

Question 22

At low doses,MDMA is ___________ while at high doses it produces __________ pharmacological effects.

A)hallucinogenic; anxiolytic
B)hallucinogenic; amphetaminelike
C)amphetaminelike; hallucinogenic
D)anxiolytic; hallucinogenic

Question 23

Piperazine was originally developed as an __________ drug.

A)antibipolar
B)anxiolytic
C)anticonvulsant
D)antihelminthic

Question 24

When taken orally,mescaline produces effects _____ after consumption.

A) to 1 hour
B)1 to 2 hours
C)2 to 3 hours
D)3 to 4 hours

Question 25

The drug __________ can be used to treat malignant hyperthermia.

A)MDMA
B)physostigmine
C)dantrolene
D)ayahuasca

Question 26

MDMA is thought to work by:

A)inhibiting reuptake of monoamines.
B)inhibiting release of GABA.
C)enhancing release of acetycholine.
D)activating glutamate receptors

Question 27

The effective dose for LSD is approximately __________ milligrams.

A)5
B)50
C)10
D)75

Question 28

Malignant hyperthermia is associated with:

A)DMT.
B)LSD.
C)MDMA.
D)scopolamine.

Question 29

_____ is officially used in religious practice of the Native American Church of North America.

A)LSD
B)Peyote
C)Psilocybin
D)MDMA

Question 30

MDMA is thought to work by:

A)inhibiting reuptake of acetylcholine.
B)inhibiting release of GABA.
C)enhancing release of monoamines.
D)activating glutamate receptors

Question 31

Myristicin and elemicin induce effects that are most similar to the psychedelic:

A)PCP.
B)mescaline.
C)scopolamine.
D)LSD.

Question 32

All of the following are serotonergic psychedelics EXCEPT:

A)LSD.
B)DOM.
C)DMT.
D)bufotenine.

Question 33

Serotonergic psychedelics are thought to work primarily by activating which of the following:

A)presynaptic receptors.
B)postsynaptic receptors.
C)neurotransmitter release.
D)reuptake inhibition.

Question 34

The effects of MDMA on __________ are controversial and have not been confirmed.

A)emotion
B)memory
C)depression
D)body temperature

Question 35

Malignant hyperthermia can be caused by _____ and treated by _____.

A)peyote; dantrolene
B)peyote; physostigmine
C)MDMA; dantrolene
D)MDMA; physostigmine

Question 36

The drug __________ is mostly related to the drugs "T7," "tripstay," "blue mystic," and "nexus."

A)DMT
B)LSD
C)MDMA
D)scopolamine

Question 37

"Ecstasy" (MDMA)use is commonly associated with reports of:

A)hypothermia.
B)empathy.
C)anger.
D)depression.

Question 38

The psychedelic chemical _____ occurs naturally in peyote.

A)myristicin
B)mescaline
C)elemicin
D)MDMA

Question 39

Barry recently took a hit of LSD.Immediately afterward,he experiences sympathomimetic effects such as an elevation of body temperature and dilation of his pupils.He is most likely in the __________ phase of the LSD experience.

A)sensory
B)perceptual
C)psychic
D)somatic

Question 40

MDMA is an _____ to _____.

A)agonist; acetylcholine
B)agonist; serotonin
C)antagonist; acetylcholine
D)antagonist; serotonin

Question 41

Psychedelic therapy involved the administration of:

A)LSD.
B)bufotenine.
C)harmine.
D)psilocybin.

Question 42

Ketamine is thought to be _____ to dopamine and _____ to acetylcholine.

A)agonistic; agonistic
B)agonistic; antagonistic
C)antagonistic; agonistic
D)antagonistic; antagonistic

Question 43

Ketamine primarily affects the neurotransmitter:

A)opioid
B)GABA
C)glutamate
D)serotonin

Question 44

Bufotenine is a compound that originates:

A)artificially.
B)in toads.
C)in certain kinds of mushrooms.
D)in various green plants.

Question 45

______ produces little respiratory depression prompting its use as a safer anesthetic in specific patient populations.

A)Ketamine
B)DMT
C)Phencyclidine
D)Ololiuqui

Question 46

The _____ phase of LSD takes place during the drug's maximum effect.

A)sensory
B)perceptual
C)psychic
D)somatic

Question 47

Phencyclidine and ketamine are both classified as an _____ to the _____ receptor.

A)agonist; muscarinic
B)agonist; NMDA
C)antagonist; muscarinic
D)antagonist; NMDA

Question 48

The psychedelic drug _____ naturally occurs in seeds.

A)LSD
B)bufotenine
C)harmine
D)psilocybin

Question 49

__________ is being investigated as a possible antidepressant since injections produce rapid antidepressant effects in treatment-resistant populations.

A)Methoxetamine
B)DMT
C)Phencyclidine
D)Ketamine

Question 50

__________ has been used to treat hallucinogen persisting perception disorder (HPPD).

A)Benzodiazepine
B)Physostigmine
C)Dantrolene
D)Ayahuasca

Question 51

The elimination half-life of phencyclidine is _____ hours.

A)2
B)4
C)8
D)10 or more

Question 52

Ketamine can induce _____ schizophrenic symptoms.

A)negative
B)positive
C)negative and positive
D)mild

Question 53

Psilocybin is a compound that originates:

A)artificially.
B)in toads.
C)in certain kinds of mushrooms.
D)in various green plants.

Question 54

LSD has a relatively _____ level of toxicity in terms of its lethal dose.

A)low
B)medium
C)high
D)extremely high

Question 55

LSD was used to treat __________ in the 1950s.

A)anxiety
B)depression
C)alcoholism
D)opioid addiction

Question 56

The risk of a lethal overdose of LSD is:

A)low.
B)medium.
C)high.
D)extremely high.

Question 57

The short-acting effects of _____ have earned it the nickname "the lunch-hour drug."

A)LSD
B)MDMA
C)DMT
D)MDA

Question 58

Phencyclidine can affect all of the following neurotransmitters EXCEPT:

A)acetylcholine
B)dopamine
C)glutamate
D)serotonin

Question 59

Phencyclidine is _____ to _____.

A)agonistic; acetylcholine
B)agonistic; glutamate
C)antagonistic; acetylcholine
D)antagonistic; glutamate

Question 60

Oral ingestion of __________ is not an effective means of administration.

A)LSD
B)psilocin
C)psilocybin
D)DMT

Question 61

Ulcerative colitis is related to the drug:

A)DMT.
B)MDMA.
C)ketamine.
D)psilocybin.

Question 62

_____ is a common ingredient in medications aimed at cough suppression.

A)DMT
B)DXM
C)LSD
D)PCP

Question 63

The effects of salvinorin A do not appear to involve the __________ receptor.

A)kappa
B)5-HT_2A
C)5-HT₁
D)nicotinic

Question 64

Preparations of salvinorin A have historically been used to treat:

A)depression.
B)anxiety.
C)diarrhea.
D)chronic pain.

Question 65

With regard to lethality,phencyclidine has a(n)_____ margin of safety.

A)low
B)medium
C)high
D)unknown

Question 66

______ represent(s)a common physical sign of salvinorin A use.

A)Hyperthermia
B)Tachycardia
C)Dilated pupils
D)Hypothermia