Contemporary Clinical Immunology and Serology 1st Edition by Kate Rittenhouse Olson,Ernesto DeNardin

Exercise 7

Peter comes to his physician's office complaining of being cold all the time, having poor energy, and gaining weight. He mentions to the physician that his sister has the same symptoms. A section of monkey thyroid incubated with the patient's serum shows staining that is not nuclear. The titer of serum that yields positive staining is 1:25 000. He has a cellular infiltrate in the affected organ. What disease do Peter and his sister have?
A) Graves' disease
B) Hashimoto's disease
C) multiple sclerosis
D) myasthenia gravis