Genetics: Analysis and Principles 4th Edition by Robert Brooker

Exercise 12

What parts of a nucleotide (namely, phosphate, sugar, and/or bases) occupy the major and minor grooves of double-stranded DNA, and what parts are found in the DNA backbone If a DNA-binding protein does not recognize a specific nucleotide sequence, do you expect that it recognizes the major groove, the minor groove, or the DNA backbone Explain.