Genetics: Analysis and Principles 4th Edition by Robert Brooker

Exercise 6

According to the examples shown in Figure 12.5, which positions of the 35 sequence (i.e., first, second, third, fourth, fifth, or sixth) are more tolerant of changes Do you think these positions play a more or less important role in the binding of factor Explain why.
FIGURE 12.5 Examples of 35 and 10 sequences within several E. coli promoters. This figure shows the 35 and 10 sequences for one DNA strand found in seven different E. coli promoters. The consensus sequence is shown at the bottom. The spacer regions contain the designated number of nucleotides between the 35 and 10 region or between the 10 region and the transcriptional start site. For example, N 17 means there are 17 nucleotides between the end of the 35 region and the beginning of the 10 region.