Genetics: Analysis and Principles 4th Edition by Robert Brooker

Exercise 12

The glucocorticoid receptor and the CREB protein are two examples of transcriptional activators. These proteins bind to response elements and activate transcription. (Note: The answers to this question are not directly described in this chapter. You have to rely on your understanding of the functioning of other proteins that are modulated by the binding of effector molecules, such as the lac repressor.)
A. How would the function of the glucocorticoid receptor be shut off
B. What type of enzyme would be needed to shut off the activation of transcription by the CREB protein