Chat with AI
Human Heredity 11th Edition by Michael Cummings
Edition 11ISBN: 978-1305251052Human Heredity 11th Edition by Michael Cummings
Edition 11ISBN: 978-1305251052 Exercise 27
DNA Sequencing
In 1977, Fred Sanger and his colleagues started the field of genomics (the study of genomes) by applying a newly developed method to sequence the 5,400 nucleotides in the genome of a virus called F X 174 (phi-X-174). The procedure was slow and laborious, and over the next few years only the very small genomes of other viruses were sequenced. Fast-forward 24 years to June 2001, to the announcement in the White House Rose Garden that a draft sequence of the 3.2 billion nucleotides in the human genome had been finished. The final human genome sequence, some 600,000 times larger than F X 174, was published in 2003. In the decades between those important milestones, the development of newer, automated sequencing methods made it possible to sequence the larger and more complex genomes of eukaryotes, including the 3.2 billion nucleotides that make up the human genome. The development of this technology was slow. The first genome of a free-living organism, a bacterium with 1,830,000 nucleotides in its genome, was not sequenced until 1995, 18 years after Sanger's work.
Progress in DNA sequencing was accelerated by the development of automated DNA sequencing machines and software to store, manipulate, and analyze DNA sequence information. Newer techniques are again revolutionizing DNA sequencing, and lowering the cost of sequencing someone's genome to about $1,000. Rapid, inexpensive genome sequencing is now available and may become a routine part of medical care. This may enable physicians to determine whether someone has a genetic disorder or which predispositions to disease are present in their genome. This information will allow individuals to make lifestyle decisions to reduce the risk or impact of genetically determined disorders and to begin treatment as symptoms develop.
In addition to genome projects, DNA sequencing is used for applications that include drug discovery and development, identification of disease-causing organisms, analysis of environmental contaminants, and conservation. Along with cloning and PCR, DNA sequencing is one of the basic methods in recombinant DNA technology.
Would you allow your genome sequence to be used in conjunction with your medical records for research?
In 1977, Fred Sanger and his colleagues started the field of genomics (the study of genomes) by applying a newly developed method to sequence the 5,400 nucleotides in the genome of a virus called F X 174 (phi-X-174). The procedure was slow and laborious, and over the next few years only the very small genomes of other viruses were sequenced. Fast-forward 24 years to June 2001, to the announcement in the White House Rose Garden that a draft sequence of the 3.2 billion nucleotides in the human genome had been finished. The final human genome sequence, some 600,000 times larger than F X 174, was published in 2003. In the decades between those important milestones, the development of newer, automated sequencing methods made it possible to sequence the larger and more complex genomes of eukaryotes, including the 3.2 billion nucleotides that make up the human genome. The development of this technology was slow. The first genome of a free-living organism, a bacterium with 1,830,000 nucleotides in its genome, was not sequenced until 1995, 18 years after Sanger's work.
Progress in DNA sequencing was accelerated by the development of automated DNA sequencing machines and software to store, manipulate, and analyze DNA sequence information. Newer techniques are again revolutionizing DNA sequencing, and lowering the cost of sequencing someone's genome to about $1,000. Rapid, inexpensive genome sequencing is now available and may become a routine part of medical care. This may enable physicians to determine whether someone has a genetic disorder or which predispositions to disease are present in their genome. This information will allow individuals to make lifestyle decisions to reduce the risk or impact of genetically determined disorders and to begin treatment as symptoms develop.
In addition to genome projects, DNA sequencing is used for applications that include drug discovery and development, identification of disease-causing organisms, analysis of environmental contaminants, and conservation. Along with cloning and PCR, DNA sequencing is one of the basic methods in recombinant DNA technology.
Would you allow your genome sequence to be used in conjunction with your medical records for research?
Explanation
Verified
Verified
Yes. To allow the use of a person's geno...
Human Heredity 11th Edition by Michael Cummings
Why don’t you like this exercise?
Other Minimum 8 character and maximum 255 character
Character 255
