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Clinical Laboratory Hematology 3rd Edition by Shirlyn McKenzie, Lynne Williams
Edition 3ISBN: 978-0133076011Clinical Laboratory Hematology 3rd Edition by Shirlyn McKenzie, Lynne Williams
Edition 3ISBN: 978-0133076011 Exercise 24
Jack, a 12-year-old male, was brought to his family physician for evaluation of right-upper-quadrant pain. He has a lifelong history of hemolytic and aplastic crises.
Consider why this patient history is important when selecting and evaluating laboratory tests.
The patient's peripheral smear revealed numerous elliptocytes, spherocytes, teardrop cells, and micropoikilocytes.
Jack's osmotic fragility test revealed the following:
A thermal sensitivity test demonstrated that Jack's erythrocytes fragment when incubated for 10 minutes at 46°C.
This case study depicts a young man who presented with right-upper-quadrant pain. The CBC disclosed anemia with a decreased MCV and increased MCHC. The peripheral blood smear revealed numerous elliptocytes, teardrop cells, and micropoikilocytes. The patient's erythrocytes demonstrated increased osmotic fragility and thermal sensitivity.
What disorder do the patient's lab findings suggest?
Consider why this patient history is important when selecting and evaluating laboratory tests.
The patient's peripheral smear revealed numerous elliptocytes, spherocytes, teardrop cells, and micropoikilocytes.
Jack's osmotic fragility test revealed the following:
A thermal sensitivity test demonstrated that Jack's erythrocytes fragment when incubated for 10 minutes at 46°C.
This case study depicts a young man who presented with right-upper-quadrant pain. The CBC disclosed anemia with a decreased MCV and increased MCHC. The peripheral blood smear revealed numerous elliptocytes, teardrop cells, and micropoikilocytes. The patient's erythrocytes demonstrated increased osmotic fragility and thermal sensitivity.
What disorder do the patient's lab findings suggest?
Explanation
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Inheritance of Hereditary elliptocytosis...
Clinical Laboratory Hematology 3rd Edition by Shirlyn McKenzie, Lynne Williams
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