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Clinical Laboratory Hematology 3rd Edition by Shirlyn McKenzie, Lynne Williams
Edition 3ISBN: 978-0133076011Clinical Laboratory Hematology 3rd Edition by Shirlyn McKenzie, Lynne Williams
Edition 3ISBN: 978-0133076011 Exercise 14
A pathologist is looking at the bone marrow aspirate of a 26-year-old male. The marrow is packed with undifferentiated blasts. After careful searching, she could not find any Auer rods. She thinks that the patient most probably has acute lymphoblastic leukemia but cannot rule out AML by using morphology.
The pathologist is thinking of ordering a TdT stain on the slides. Is that going to be useful? (Objectives 8, 9)
A) Yes, TdT is always positive in acute lymphoid leukemia but never in myeloid leukemia.
B) Yes, TdT is always positive in acute myeloid leukemia but never in lymphoid leukemia.
C) No, TdT is positive in the majority of acute lymphoid leukemias, but approximately 20% of acute myeloid leukemias can be positive.
D) No, TdT is positive in the majority of acute myeloid leukemias, but approximately 20% of acute lymphoid leukemias can be positive.
The pathologist is thinking of ordering a TdT stain on the slides. Is that going to be useful? (Objectives 8, 9)
A) Yes, TdT is always positive in acute lymphoid leukemia but never in myeloid leukemia.
B) Yes, TdT is always positive in acute myeloid leukemia but never in lymphoid leukemia.
C) No, TdT is positive in the majority of acute lymphoid leukemias, but approximately 20% of acute myeloid leukemias can be positive.
D) No, TdT is positive in the majority of acute myeloid leukemias, but approximately 20% of acute lymphoid leukemias can be positive.
Explanation
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Presence of Auer rods positively confirm...
Clinical Laboratory Hematology 3rd Edition by Shirlyn McKenzie, Lynne Williams
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