
iGenetics 3rd Edition by Peter Russell
Edition 3ISBN: 978-0321569769
iGenetics 3rd Edition by Peter Russell
Edition 3ISBN: 978-0321569769 Exercise 6
Some complete loss-of-function mutations result from a deletion of just one gene or a missense mutation that results in a completely nonfunctional protein
a. If such mutations were obtained in each of the lacA , lacI , lacY , and lacZ genes, which would show a lac phenotype (be unable to grow using lactose as a sole carbon source)? What properties would the other(s) show?
b. If such mutations were obtained in each of the trpA , trpB , trpC , trpD , and trpR genes, which would show a trp phenotype (require supplemental tryptophan for growth)? What properties would the other(s) show?
c. If such mutations were obtained in each of the araA , araB , araC , and araD genes, which would show an ara phenotype (be unable to grow using arabinose as the sole carbon source)? What properties would the other(s) show?
a. If such mutations were obtained in each of the lacA , lacI , lacY , and lacZ genes, which would show a lac phenotype (be unable to grow using lactose as a sole carbon source)? What properties would the other(s) show?
b. If such mutations were obtained in each of the trpA , trpB , trpC , trpD , and trpR genes, which would show a trp phenotype (require supplemental tryptophan for growth)? What properties would the other(s) show?
c. If such mutations were obtained in each of the araA , araB , araC , and araD genes, which would show an ara phenotype (be unable to grow using arabinose as the sole carbon source)? What properties would the other(s) show?
Explanation
(1) The function of the three proteins p...
iGenetics 3rd Edition by Peter Russell
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