Becker's World of the Cell 9th Edition by Lewis Kleinsmith, Jeff Hardin, Gregory Paul Bertoni

Exercise 6

Spongy Actin. You are interested in the detailed effects of cytochalasin D on microfilaments over time. Based on what you know about the molecular mechanism of action of cytocha- lasins, draw diagrams of what happens to microfilaments within cells treated with the drug. In particular, explain why existing actin polymers eventually depolymerize.