
Becker's World of the Cell 9th Edition by Lewis Kleinsmith, Jeff Hardin, Gregory Paul Bertoni
Edition 9ISBN: 9780134295510
Becker's World of the Cell 9th Edition by Lewis Kleinsmith, Jeff Hardin, Gregory Paul Bertoni
Edition 9ISBN: 9780134295510 Exercise 3
Sleuthing Using Mutants. An mRNA contains the following sequence:
5 ...CAACUGCCUGACCCACACUUAUCACUAAG
UAGCCUAGCAGUCUGA...3
The wild-type amino acid sequence encoded by this piece of the mRNA is as follows:
N... Asn-Cys-Leu-Thr-His-Thr-Tyr-His-C
The C-terminal ends of three mutant proteins resulting from mutations in the gene encoding this mRNA are as follows:
Mutant 1: N...Asn-Cys-Leu-Thr-His-Thr-C
Mutant 2: N...Asn-Cys-Leu-Thr-His-Thr-Tyr-His-Lys-C
Mutant 3: N...Asn-Cys-Leu-Thr-His-Thr-Tyr-His-Tyr-Ser-Ser-Leu-Ala-Val-C
Identify the mutations in each case that result in these mutant proteins.
5 ...CAACUGCCUGACCCACACUUAUCACUAAG
UAGCCUAGCAGUCUGA...3
The wild-type amino acid sequence encoded by this piece of the mRNA is as follows:
N... Asn-Cys-Leu-Thr-His-Thr-Tyr-His-C
The C-terminal ends of three mutant proteins resulting from mutations in the gene encoding this mRNA are as follows:
Mutant 1: N...Asn-Cys-Leu-Thr-His-Thr-C
Mutant 2: N...Asn-Cys-Leu-Thr-His-Thr-Tyr-His-Lys-C
Mutant 3: N...Asn-Cys-Leu-Thr-His-Thr-Tyr-His-Tyr-Ser-Ser-Leu-Ala-Val-C
Identify the mutations in each case that result in these mutant proteins.
Explanation
The wild type amino acid sequence is:
N-...
Becker's World of the Cell 9th Edition by Lewis Kleinsmith, Jeff Hardin, Gregory Paul Bertoni
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