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Lab Manual and Workbook in Microbiology 11th Edition by Josephine Morello ,Paul Granato,Verna Morton
Edition 11ISBN: 978-0073402390Lab Manual and Workbook in Microbiology 11th Edition by Josephine Morello ,Paul Granato,Verna Morton
Edition 11ISBN: 978-0073402390 Exercise 7
A Case of Pneumonia with Meningitis
A 78-year-old woman developed rapid onset of fever and a shaking chill. She had difficulty breathing and produced thick (mucopurulent), rust-colored sputum. Shortly thereafter, she developed a headache, lethargy, and a stiff neck and lapsed into a coma. She was admitted to the hospital where blood, sputum, and cerebrospinal fluid specimens were obtained for culture. The laboratory shortly reported that Gram-stained smears of the sputum and cerebrospinal fluid revealed gram-positive, lancet-shaped diplococci. The patient was treated with intravenous antimicrobial agents, woke up from the coma, and recovered without incident.
What is the major virulence factor of this organism?
A 78-year-old woman developed rapid onset of fever and a shaking chill. She had difficulty breathing and produced thick (mucopurulent), rust-colored sputum. Shortly thereafter, she developed a headache, lethargy, and a stiff neck and lapsed into a coma. She was admitted to the hospital where blood, sputum, and cerebrospinal fluid specimens were obtained for culture. The laboratory shortly reported that Gram-stained smears of the sputum and cerebrospinal fluid revealed gram-positive, lancet-shaped diplococci. The patient was treated with intravenous antimicrobial agents, woke up from the coma, and recovered without incident.
What is the major virulence factor of this organism?
Explanation
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The bacterial capsule of Streptococcus p...
Lab Manual and Workbook in Microbiology 11th Edition by Josephine Morello ,Paul Granato,Verna Morton
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