Biology 8th Edition by Kenneth Mason ,Jonathan Losos,Susan Singer,Peter Raven,George Johnson

Exercise 3

Phosphofructokinase functions to add a phosphate group to a molecule of fructose-6-phosphate. This enzyme functions early in glycolysis, an energy-yielding biochemical pathway discussed in chapter 7. The enzyme has an active site that binds fructose and ATP. An allosteric inhibitory site also binds ATP when cellular levels of ATP are very high.
A) Predict the rate of the reaction if the levels of cellular ATP are low.
B) Predict the rate of the reaction if levels of cellular ATP are very high.
C) Describe what is happening to the enzyme when levels of ATP are very high.