Essential Genetics 6th Edition by Daniel Hartl

Exercise 21

The accompanying pedigree and gel diagram show the molecular phenotypes obtained from genomic DNA samples. The bands are characteristic DNA fragments that distinguish two alleles of a single gene. What mode of inheritance does the pedigree suggest? On the basis of this hypothesis, and using A1 to represent the allele associated with the 4-kb band and A2 to represent the allele associated with the 9-kb band, deduce the genotype of each individual in the pedigree.