Biology 2nd Edition by Robert Brooker, Eric Widmaier ,Linda Graham ,Peter Stiling

Exercise 13

Which statement best describes the extrinsic pathway for apoptosis
A) Caspases recognize an environmental signal and expose their death domain.
B) Death receptors recognize an environmental signal, which then leads to the activation of caspases.
C) Initiator caspases digest the nuclear lamina and cytoskeleton.
D) Executioner caspases are part of the death-inducing signaling complex (DISC).
E) All of the above are true of the extrinsic pathway.