Biology of Humans 4th Edition by Judith Goodenough,Betty McGuire

Exercise 15

The following are base sequences in four mRNA strands: one normal and three with mutations. (Keep in mind that transla- tion begins with a start codon and ends with a stop codon.) Which of the mutated sequences is likely to have the most severe effects? Why? Which would have the least severe effects? Why? Normal mRNA: AUG ACA UAU GAG ACG ACU Mutation 1: AUG ACC UAC GAA ACG ACC Mutation 2: AUG ACU UAA GAG ACG ACA Mutation 3: AUG ACG UAU GAG ACG ACG