
Bioprocess Engineering 2nd Edition by Fikret Kargi,Michael Shuler
Edition 2ISBN: 9780130819086
Bioprocess Engineering 2nd Edition by Fikret Kargi,Michael Shuler
Edition 2ISBN: 9780130819086 Exercise 8
Uric acid is degraded by uricase enzyme immobilized in porous Ca-alginate beads. Experi-
ments conducted with different bead sizes result in the following rate data:
a. Determine the effectiveness factor for particle sizes Dp = 0.5 cm and Dp = 0.7 cm.
b. The following data were obtained for Dp = 0.5 cm at different bulk uric acid concentra-
tions. Assuming negligible liquid film resistance, calculate
for the enzyme. As-
sume no substrate or product inhibition.

ments conducted with different bead sizes result in the following rate data:
a. Determine the effectiveness factor for particle sizes Dp = 0.5 cm and Dp = 0.7 cm.
b. The following data were obtained for Dp = 0.5 cm at different bulk uric acid concentra-
tions. Assuming negligible liquid film resistance, calculate
for the enzyme. As-sume no substrate or product inhibition.

Explanation
The effectiveness factor depicts the rel...
Bioprocess Engineering 2nd Edition by Fikret Kargi,Michael Shuler
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