Microbiology 9th Edition by Laura Black, Jacquelyn Black

Exercise 5

Put the following events of the acute phase response in order:
(a)--The acute phase proteins can now activate the com plement system and immune cytolysis and stimulate phagocyte chemotaxis.
(b)--C-reactive protein recognizes and binds to phos pholipids and mannose-binding protein to mannose sugars, in cell membranes of many bacteria and the plasma membrane of fungi.
(c)--Interleukin-6 reaches the liver via the bloodstream where it causes the liver to synthesize and secrete the acute phase proteins (C-reactive and mannose binding proteins) into the blood.
(d)--Once bound, the acute phase proteins act like opsonins.
(e)--Macrophage ingestion of microbe stimulates synthe sis and secretion of interleukin-6