Microbiology 9th Edition by Laura Black, Jacquelyn Black

Exercise 15

Put the following steps in order for cell-mediated immune reactions:
(a) Differentiated T cells include T helper, delayed hyper sensitivity, cytotoxic, and memory T cells that all have different immunological functions depending on the an tigen presented.
(b) Antigen-presenting cells (macrophages and dendritic cells) phagocytize pathogens, ingesting and degrading them into pieces which are transported to the surface of the cell.
(c) T cells bearing the corresponding receptor for the pre sented antigen bind to it and become activated only if the appropriate MHC is also present.
(d) Some pieces of the pathogen's antigens are processed by inserting them into the antigen-presenting cell's membrane and are held in place by class II major histocompatibility complex (MHCII) proteins.
(e) Activated T cells are stimulated to divide and differen tiate into different types of T cells, including memory cells