Deck 59: Antifungal and Antiviral Drugs

Question 1

The nurse would carefully monitor the results of which of the following laboratory studies during drug therapy with amphotericin B (Fungizone)?

A) Hemoglobin
B) Sodium
C) Phosphate level
D) Blood urea nitrogen

Answer 1

Blood urea nitrogen

Question 2

The nurse explains to a client who is beginning drug therapy with griseofulvin (Grisactin)that which of the following is the most common adverse effect?

A) Headache
B) Bitter taste in the mouth
C) Gingivitis
D) Ringing in the ears

Answer 2

Headache

Question 3

The nurse anticipates that which of the following drugs will be used to treat fungal endocarditis caused by the Candida species?

A) Amphotericin B (Fungizone)
B) Fluconazole (Diflucan)
C) Flucytosine (Ancobon)
D) Griseofulvin (Fulvicin)

Answer 3

Flucytosine (Ancobon)

Question 4

An 18-year-old female client has been diagnosed with genital herpes.The nurse anticipates that which of the following drugs will be used to treat and manage this infection?

A) Amantadine (Symmetrel)
B) Acyclovir (Zovirax)
C) Zidovudine (Retrovir)
D) Ribavirin (Virazole)

Question 5

The nurse would explain to a male client taking ketoconazole (Nizoral)that which of the following is a rare adverse drug effect that should be reported to the prescriber if it occurs?

A) Priapism
B) Impotence
C) Urinary hesitancy
D) Burning on urination

Question 6

The nurse would consult the prescriber regarding a new order for griseofulvin (Grisactin)if the client routinely needs to follow which of the following types of diets?

A) Low-salt
B) Low-protein
C) Low-carbohydrate
D) Low-fat

Question 7

Acyclovir (Zovirax)is selectively taken up by which of the following microorganisms?

A) Proteus vulgaris
B) Pneumocystis carinii
C) Herpes zoster
D) Staphylococcus aureus

Question 8

The client is taking an oral itraconazole (Sporanox)capsule for treatment of a fungal infection.The nurse explains that the client should not take which of the following over-the-counter products that could reduce drug absorption?

A) Multivitamin
B) Acetaminophen (Tylenol)
C) Ibuprofen (Motrin)
D) Ranitidine (Zantac)

Question 9

Which of the following statements reflects appropriate instructions for the female client with genital herpes?

A) "Using spermicidal jellies and foams will help prevent the spread of herpes."
B) "You will be disease free 72 hours after taking the medication."
C) "Partners do need not be treated because this disease is not retransmittable."
D) "Herpes genitalis is transmitted sexually,so avoid unprotected intercourse."

Question 10

The nurse assesses which of the following body systems for evidence of amantadine (Symmetrel)toxicity?

A) The central nervous system
B) The skin
C) The muscle
D) The endocrine system

Question 11

A client is receiving caspofungin (Cancidas)for a fungal infection.The nurse interprets that the client could be experiencing adverse drug effects after noting which of the following laboratory test results?

A) Potassium 5.2 mEq/L
B) Blood urea nitrogen 32 mg/dL
C) Sodium 142 mEq/L
D) Partial thromboplastin time 35 seconds

Question 12

A client with AIDS and cytomegalovirus retinitis has a new drug order for cidofovir (Vistide).The nurse asks the prescriber about an order for which drug that should be taken concurrently to reduce renal toxicity?

A) Mannitol (Osmitrol)
B) Acetylsalicylic acid (aspirin)
C) Probenecid (Benemid)
D) Furosemide (Lasix)

Question 13

A parent tells the pediatric clinic nurse that she has heard that acyclovir (Zovirax)can be used to treat chickenpox in children.In responding to the parent,the nurse affirms that acyclovir may be useful if drug therapy is begun within how many hours of appearance of the rash?

A) 8
B) 16
C) 24
D) 48

Question 14

The nurse who notes muscular weakness and abdominal distention in a client receiving amphotericin B (Fungizone)concludes that the client is experiencing which of the following adverse drug effects?

A) Hypercalcemia
B) Hypokalemia
C) Leukocytosis
D) Agranulocytosis

Question 15

The nurse anticipates that which of the following drugs will be used to manage viral pneumonia in a client with respiratory syncytial virus?

A) Amantadine (Symmetrel)
B) Flucytosine (Ancobon)
C) Griseofulvin (Grisactin)
D) Ribavirin (Virazole)

Question 16

The nurse would interpret that which of the following trends in laboratory values is consistent with an adverse effect of flucytosine (Ancobon)?

A) Increasing white blood cell count
B) Decreasing platelet count
C) Increasing uric acid level
D) Decreasing blood glucose level

Question 17

To reduce the adverse effects of intravenous acyclovir (Zovirax)on the kidneys,the nurse should plan to do which of the following?

A) Infuse the dose over a 1-hour period and encourage fluids for 2 additional hours
B) Infuse the dose over a 2-hour period and encourage fluids for 4 additional hours
C) Infuse the dose over a 30-minute period and encourage fluids for 1 additional hour
D) Infuse the dose over a 90-minute period and encourage fluids for an additional half hour

Question 18

A client with a fungal infection is taking fluconazole (Diflucan).The nurse explains that although this drug is generally well tolerated,possible adverse effects include which of the following?

A) Gastrointestinal upset
B) Constipation
C) Dizziness
D) Ringing in the ears

Question 19

A client is taking fluconazole (Diflucan).The nurse is most concerned about which of the following during drug therapy?

A) Poor adherence to therapy because of drug taste
B) Risk of interactions with other drugs
C) Cost of medication therapy
D) Risk of drug resistance

Question 20

The nurse is assigned to a client on the telemetry unit who is receiving voriconazole (Vfend).The nurse would assess for which of the following changes in the client's cardiac rhythm strip to detect an adverse drug reaction?

A) Shortened PR interval
B) Biphasic P wave
C) Prolonged QT interval
D) Tall T wave

Question 21

A client with hepatitis C has an order for ribavirin (Virazole).The nurse expects to administer the dose by which of the following typical routes for this health problem?

A) Oral
B) Subcutaneous
C) Intravenous
D) Inhalation

Question 22

The nurse would assess the client for exacerbation of which concurrent health problem when taking amprenavir (Agenerase)?

A) Hypertension
B) Diabetes
C) Urinary tract infection
D) Glaucoma

Question 23

The nurse would assess the client taking nevirapine (Viramune)for adverse drug effects from increased serum levels after learning that the client is also taking which of the following drugs?

A) Fluconazole (Diflucan)
B) Rifampin (Rifadin)
C) Phenytoin (Dilantin)
D) Carbamazepine (Tegretol)

Question 24

The nurse concludes that which of the following symptoms reported by a client taking zidovudine (AZT)is not likely to be the result of an adverse drug effect?

A) Excessive sleepiness
B) Nausea
C) Joint pain
D) Weakness

Question 25

The nurse who is teaching a client about the newly ordered drug nevirapine (Viramune)explains that it belongs to which of the following classes of antivirals?

A) Nucleoside reverse transcriptase inhibitor
B) Nonnucleoside reverse transcriptase inhibitor
C) Protease inhibitor
D) Fusion inhibitor

Question 26

A client will begin drug therapy with valganciclovir (Valcyte).The nurse should give the client which of the following instructions related to self-administration of this drug?

A) Reduce fluid intake during therapy
B) Take dose on an empty stomach
C) Sit upright for 30 minutes after the dose
D) Do not break or crush the tablet

Question 27

A client is receiving ribavirin (Virazole)for treatment of respiratory syncytial virus.The nurse plans to administer the ordered dose by which of the following appropriate routes?

A) Oral
B) Subcutaneous
C) Intravenous
D) Inhalation

Question 28

The nurse who is teaching a client about the newly ordered drug enfuvirtide (Fuzeon)explains that it belongs to which of the following classes of antivirals?

A) Nucleoside reverse transcriptase inhibitor
B) Nonnucleoside reverse transcriptase inhibitor
C) Protease inhibitor
D) Fusion inhibitor

Question 29

The nurse would assess the client receiving lamivudine (Epivir)for which of the following acid-base imbalances as an adverse effect of therapy?

A) Respiratory alkalosis
B) Respiratory acidosis
C) Metabolic alkalosis
D) Lactic acidosis

Question 30

The nurse concludes that a client would not be eligible for antiviral therapy with didanosine (Videx)after learning that the client has a history of which of the following?

A) Heavy alcohol use
B) Smoking a pack of cigarettes per day
C) Chronic antiinflammatory drug therapy
D) Cytomegalovirus retinopathy

Question 31

The nurse assesses the client taking saquinavir (Invirase)for a reduction in symptoms of which of the following health problems?

A) Genital herpes
B) Herpes zoster
C) Influenza type A
D) AIDS

Question 32

The charge nurse on a nursing unit would make out the shift assignment so that which of the following nurses would not be assigned to a client receiving ribavirin (Virazole)?

A) The nurse who has not had chickenpox
B) The nurse who has a low-grade fever
C) The nurse who is pregnant
D) The nurse on light duty from a back injury

Question 33

A male client with cytomegalovirus retinitis is receiving ganciclovir (Cytovene).The nurse instructs this client to use barrier contraception during and for how long after completion of drug therapy?

A) 1 month
B) 3 months
C) 6 months
D) 12 months

Question 34

The nurse determines that a course of drug therapy with ribavirin (Virazole)has been effective when the client shows which of the following?

A) Absence of cytomegalovirus retinitis
B) Improved airway clearance
C) Healing of genital lesions
D) Resolution of skin lesions

Question 35

The nurse is admitting a client who has chronic hepatitis B infection.The nurse expects to find which of the following drugs on the client's drug order sheet?

A) Acyclovir (Zovirax)
B) Ganciclovir (Cytovene)
C) Adefovir (Hepsera)
D) Ribavirin (Virazole)