Deck 18: Serology and Viruses Herpesviridae Family and Other Serologically

Question 1

Varicella zoster is highly contagious and is spread by
a.aerosols produced by coughing and sneezing
b.aerosols of the skin lesions and direct contact with the lesion
c.A and B
d.none of the above

Answer 1

A and B

Question 2

The Paul-Bunnell antigen is associated with
a.infectious mononucleosis
b.serum sickness
c.Forssman
d.A and B
e.all of the above

Answer 2

infectious mononucleosis

Question 3

CMV infections are major causes of infection and death for
a.transplant patients
b.people with HIV
c.people with lymphoproliferative disorders
d.A and B
e.all of the above

Answer 3

all of the above

Question 4

Preventative therapy for chicken pox is
a.acyclovir
b.varicella zoster immune globulin
c.acyclovir
d.all of these

Question 5

Epstein-Barr virus is
a.spread through saliva
b.spread through transplantation
c.A and B
d.none of the above

Question 6

The Herpesviridae group members have which of the following in common?
a.have dsDNA
b.have ssDNA
c.are enveloped
d.A and C
e.B and C

Question 7

Epstein-Barr virus is associated with
a.infectious mononucleosis
b.Burkitt's lymphoma
c.nasopharyngeal carcinoma
d.A and B
e.all of the above

Question 8

Influenza exhibits antigenic
a.drift because of minor changes in the genome of the virus
b.shift because of changes in the genome of the virus
c.drift because of major changes because of gene reassortment with viruses from other species
d.B and C
e.all of the above

Question 9

To serotype HSV to determine whether the patient has HSV 1 or HSV 2, we would look for the serotype specific
a.1, 2 antigen
b.glycoprotein G antigen
c.protein P antigen
d.glycolipid antigen gL

Question 10

Herpes simplex virus
a.can cause a "cold sore" at the mouth and genital herpes
b.can be spread only when there are signs and symptoms
c.cannot be spread if a condom is worn during sexual relations
d.A and B
e.A and C

Question 11

The presence of IgM or a 4-fold increase in paired IgG titers is diagnostic for which current infection?
a.CMV
b.chicken pox
c.mumps
d.all of the above

Question 12

In a presumptive negative infectious mononucleosis patient who has all the signs and symptoms of the disease, we could double-check by testing for
a.IgM to Epstein-Barr early antigen
b.antibody to Epstein-Barr nuclear antigen
c.antibody to viral capsid antigen
d.a negative result to B and a positive result to C
e.a positive result to A and a negative result to C

Question 13

The vaccine response to which of the following diseases is not robust, so cases might be seen in people who were vaccinated?
a.measles
b.mumps
c.rubella
d.chicken pox

Question 14

Of the following concerning cytomegalovirus infectious, which of the following is true?
a.looks clinically like infectious mononucleosis
b.causes problems in 20% of babies who are infected in utero
c.cause problems in 80% of the babies who are infected in utero
d.A and B
e.A and C

Question 15

Preventative therapy for chicken pox is used in
a.full-term babies
b.individuals who are immunocompromised
c.individuals who are not immunocompromised
d.all of the above

Question 16

Which of the following diseases causes many worldwide deaths, mostly in third world countries. A partnership to increase worldwide vaccinations to prevent these deaths has been formed. The importance of the vaccine is clear, yet because of falsified results, some parents in the United States do not vaccinate their children to prevent it.
a.infectious mononucleosis
b.measles
c.HSV1
d.chicken pox

Question 17

TORCH refers to a group of tests used in postnatal care including
a.toxoplasmosis, other infections, rickettsia, chicken pox, hepatitis
b.toxoplasmosis, other infections, rubella, chicken pox, herpes simplex virus
c.toxoplasmosis, other infections, rubella, cytomegalovirus infections, herpes simplex virus
d.none of the above

Question 18

Two different antigens vary in different strains of influenza virus, and every year, a vaccine is developed to include the best choice of them. What are the antigens?
a.the hemagglutinin and the neuraminidase
b.the Paul-Bunnell and the serum sickness antigens
c.the EBNA and VCA antigens
d.GP120 and GP41

Question 19

Bill's serum tests positive for IgM anti-VCA but negative for anti-EBNA. This means that he
a.has recently recovered from infectious mononucleosis
b.currently has infectious mononucleosis
c.has a reactivation of his infectious mononucleosis
d.is well

Question 20

Shingles is caused by a reactivation of the virus that originally caused which of these infections?
a.rubella
b.infectious mononucleosis
c.chicken pox
d.rubeola
e.cytomegalovirus infection

Question 21

Serum from Chris, the snake handler, agglutinated sheep red blood cells but after absorption with either guinea pig kidney or bovine erythrocytes, it did not agglutinate the sheep red blood cells. The serum gave a positive result in the Acceava for infectious mononucleosis. Chris has
a.infectious mononucleosis
b.syphilis
c.serum sickness antibodies
d.Forssman antibodies

Question 22

The HCG pregnancy test is what type of capture assay?
a.antibody-antigen-antibody
b.antigen-antibody-antigen
c.antigen-antibody-antigen
d.antibody, antigen, antibody

Question 23

With what diseases is Epstein-Barr Virus associated?
a.infectious mononucleosis, leprosy, Burkitt's lymphoma
b.infectious mononucleosis, Burkitt's lymphoma, hepatoma
c.infectious mononucleosis, Hodgkin's lymphoma, nasal pharyngeal adenocarcinoma
d.infectious mononucleosis, Burkitt's lymphoma, nasal pharyngeal adenocarcinoma

Question 24

The new test for infectious mononucleosis is what type of capture assay?
a.antigen-antibody-antigen
b.antigen-antibody-antigen
c.antibody-antigen-antibody
d.antibody, antibody, antigen

Question 25

What kind of red blood cells are used in infectious mononucleosis absorption?
a.guinea pig red blood cells
b.human red blood cells and bovine red blood cells
c.horse red blood cells and sheep red blood cells
d.bovine red blood cells

Question 26

Which of the following defines heterophile antigen?
a.an antigen that is present in different species in relation to the evolutionary relationship of the animals
b.an antigen that is present in different species but not in relation to the evolutionary relationship of the animals
c.an antibody that is similar in different species
d.an antibody that reacts with antigen that is present in different species in relation to the evolutionary relationship of the animals

Question 27

What three types of antibody can cause a positive presumptive test for infectious mononucleosis?
a.infectious mononucleosis, malaria, serum sickness
b.infectious mononucleosis, serum sickness, pregnancy
c.infectious mononucleosis, healthy humans with Forssman ab, serum sickness
d.infectious mononucleosis, leprosy, healthy human