Deck 47: Antifungal Drugs

Question 1

Which antifungal drug causes increased effects of oral anticoagulants?

A)miconazole
B)fluconazole
C)ketoconazole
D)amphotericin B (Fungizone)

Answer 1

fluconazole

Question 2

A patient is receiving therapy with amphotericin B (Fungizone).The nurse will monitor for known adverse effects that are reflected by which laboratory result?

A)A serum potassium level of 2.9 mmol/L
B)A serum potassium level of 5.6 mmol/L
C)A white blood cell count of 6 500 mm3
D)A platelet count of 300 000 per microlitre

Answer 2

A serum potassium level of 2.9 mmol/L

Question 3

The nurse is administering amphotericin B (Fungizone).Which actions by the nurse are appropriate? (Select all that apply.)Express your answer by using small letters followed by a comma and a space (e.g.,a,b,c,d).

A)Administering the medication by rapid IV infusion
B)Discontinuing the drug immediately if the patient develops tingling and numbness in the extremities
C)If adverse effects occur, reducing the IV rate gradually until the adverse effects subside
D)Using an infusion pump with IV therapy
E)Monitoring the IV site for signs of phlebitis and infiltration
F)Administering premedication for fever and nausea as ordered
G)Ensuring that the IV solution for amphotericin B is cloudy
H)Monitoring for muscle twitching, which may indicate hypokalemia

Answer 3

Discontinuing the drug immediately if the patient develops tingling and numbness in the extremities
Using an infusion pump with IV therapy
Monitoring the IV site for signs of phlebitis and infiltration
Administering premedication for fever and nausea as ordered

Question 4

A patient has been prescribed a vaginal antifungal drug.What important information should the nurse teach the patient about this drug?

A)The medication is to be continued even if menstruation begins.
B)The health care provider should be contacted if symptoms are not gone in 48 hours.
C)Daily douching is part of the treatment for vaginal fungal infections.
D)Consumption of alcohol is to be avoided.

Question 5

Which is a contraindication to the use of griseofulvin?

A)Porphyria
B)Renal disease
C)Cardiac disease
D)Meningitis

Question 6

The nurse is administering an antifungal medication.What assessment finding may indicate medication-induced renal damage?

A)Rash and chills
B)Increased urinary output
C)Decreased levels of blood urea nitrogen (BUN) and creatinine
D)A weight gain of 2.5 kg in 1 week

Question 7

A patient has been prescribed ketoconazole.What should the nurse tell the patient to do in regard to this medication?

A)Have liver function tested.
B)Take antacids with the drug to minimize gastrointestinal upset.
C)Take the drug with a large glass of orange juice or water.
D)Take the drug 2 hours before a meal or 2 hours after a meal.

Question 8

The nurse is reviewing the history of a patient who will be taking an antifungal drug.Which condition is a contraindication to this treatment therapy?

A)Diabetes
B)Kidney failure
C)Hyperthyroidism
D)Meningitis

Question 9

Which drug may be used for invasive aspergillosis in patients who cannot tolerate other antifungal drugs?

A)fluconazole (Diflucan)
B)flucytosine (5-FC)
C)caspofungin (Cancidas)
D)nystatin

Question 10

The nurse is administering Amphotec,one of the newer formulations of amphotericin B.When giving this drug,what important information does the nurse need to remember?

A)The new formulation may be given in an oral form.
B)The newer doses are much lower than the older doses.
C)The newer doses are much higher than the older doses.
D)The newer and older forms have no differences in their doses.

Question 11

During administration of amphotericin B (Fungizone),the patient may experience severe adverse effects,such as fever,chills,hypotension,tachycardia,malaise,nausea,and headache.The correct action for the nurse to take is to

A)discontinue the infusion immediately.
B)reduce the infusion rate gradually until the adverse effects subside.
C)administer the medication by rapid intravenous (IV) infusion to reduce the potential adverse effects.
D)Anticipating these effects, pretreat the patient with an antipyretic, such as acetaminophen, an antihistamine, and an antiemetic drug.

Question 12

A patient with a severe fungal infection has been prescribed voriconazole (Vfend).Which assessment finding should the nurse be concerned about before the medication is started?

A)Decreased breath sounds in the lower lobes
B)History of cardiac dysrhythmias
C)History of type 2 diabetes
D)Potassium level of 3.8 mmol/L