Deck 49: Antibiotics Affecting Bacterial Protein Synthesis

Question 1

The nurse knows that bacterial protein synthesis inhibitors have selective toxicity because:
1)Bacteria and human ribosomes are different.
2)Susceptible strains of bacteria are affected.
3)Biochemical processes are the same.
4)Antibacterial activity is broad-spectrum.

Answer 1

1

Question 2

In which situation is it appropriate for the nurse to instruct the client to stop taking minocycline (Minocin)and promptly seek medical advice?
1)The client reports occasional nausea.
2)The client reports vaginal discharge.
3)The client reports shortness of breath.
4)The client reports epigastric burning.

Answer 2

3

Question 3

The nurse knows that antibacterial protein synthesis inhibitors act by:
1)Disrupting the polypeptide chain.
2)Promoting lysis of the cell wall.
3)Inhibiting synthesis of enzymes.
4)Disrupting cell wall synthesis.

Answer 3

1

Question 4

The nurse knows _______ is classified as a bacteriocidal protein synthesis inhibitor.
1)Erythromycin (E-mycin)
2)Gentamicin (Garamycin)
3)Tetracycline (Sumycin)
4)Clindamycin (Cleocin)

Question 5

A client reports fever and chills after five days of therapy with tetracycline.The nurse knows that drug resistance can develop in which ways? Select all that apply.
1)A drug is prevented from concentrating inside the bacterial cell.
2)Drug therapy is not completed for the prescribed duration of time.
3)A bacteriostatic agent is paired with a bacteriocidal agent.
4)The shape of the bacterial ribosome is altered to prevent a drug from binding to
It)
5)Use of a broad spectrum antibacterial drug is preferred over use of a narrow-spectrum drug.

Question 6

Which intervention will the nurse implement first when planning the care of a client diagnosed with an infection?
1)Administer the prescribed antibiotic.
2)Instruct the patient and family about adverse effects.
3)Obtain specimens for culture and sensitivity.
4)Perform an infection-focused physical examination.

Question 7

The nurse is obtaining a client's drug history prior to initiating therapy with gentamicin (Garamycin).The client takes diltiazem (Cardizem)and aspirin.Based on this information, the nurse identifies the client is at increased risk for:
1)Pseudomembranous colitis.
2)Nephrotoxicity.
3)Photosensitivity.
4)Ototoxicity.

Question 8

The nurse knows that bacterial protein transcription:
1)Is linked to the 80S ribosome.
2)Is similar to human protein synthesis.
3)Is limited to cellular reproduction.
4)Is controlled by metabolizing enzymes.

Question 9

A client is prescribed gentamicin (Garamycin)concurrently with acyclovir (Zovirax).Which of the following would be most important for the nurse to assess?
1)Visual acuity
2)Balance
3)Urine output
4)Hearing

Question 10

The nurse knows that administering an aminoglycoside as monotherapy:
1)Reduces the incidence of adverse effects.
2)Can lead to resistant bacterial strains.
3)Indicates that it is given intravenously.
4)Shortens the duration of therapy.

Question 11

Components needed for the synthesis of bacterial protein are identified by the nurse to be:
1)mRNA, tRNA, plasma membrane, and pilus.
2)mRNA, tRNA, 80S and ribosome.
3)mRNA, tRNA, and ribosome subunits 30S and 50S.
4)DNA, mRNA, cell wall, and nucleoid.

Question 12

A nurse is managing the care for a client prescribed tetracycline who is reporting frequent episodes of diarrhea.The nurse plans to monitor this client for:
1)Intestinal obstruction.
2)Pseudomembranous colitis.
3)Impaired biliary function.
4)Paralytic ileus.

Question 13

The nurse is instructing a female client about therapy with tetracycline (Sumycin).Which of the following statements by the nurse is correct?
1)"Absorption of this drug is not affected by foods."
2)"If taking oral contraceptives, an additional form of birth control is recommended."
3)"Take this drug immediately before bedtime."
4)"GI upset is a rare side effect."