Deck 34: Drugs Affecting the Renin-Angiotensin-Aldosterone System

Question 1

Angiotensin receptor blockers work in the body to lower blood pressure by:
1)Blocking AT1 receptors, which prevent angiotensin from raising blood pressure.
2)Blocking the conversion of angiotensin I to angiotensin II.
3)Blocking the formation of renin in the RAAS system.
4)Inhibiting the stimulation of aldosterone secretion.

Answer 1

1

Question 2

A client who is being treated with losartan for hypertension is instructed to avoid using alcohol because of the risk of:
1)Alcohol intoxication.
2)Lowered blood pressure.
3)Increased blood pressure.
4)Angioedema.

Answer 2

2

Question 3

The major difference in adverse effect profile between ACE inhibitors and ARBs is that ARBs do not cause:
1)Cough.
2)Angioedema.
3)Headache.
4)Dizziness.

Answer 3

1

Question 4

The most common adverse effects of lisinopril therapy are:
1)Hypertension, hypokalemia, and productive cough.
2)Rash, hypokalemia, and constipation.
3)Hypotension, Hyperkalemia, and urinary frequency.
4)Hypotension, cough, and rash.

Question 5

Angiotensinogen is a protein that is continuously circulating in the blood stream.It is synthesized where in the body?
1)The kidneys
2)The lungs
3)The liver
4)The gallbladder

Question 6

The secretion, storage, and synthesizing of renin are controlled in which cells of the kidney?
1)The juxtaglomerular cells
2)Henle's loop
3)The distal loop
4)The baroreceptors

Question 7

Which group of cells in the kidneys is considered to make up the juxtaglomerular apparatus, which helps control renin secretion?
1)The nephron and Bowman's capsule
2)The JG cells and the macula densa
3)The tubular and the glomerulus
4)The red blood cells and slit pores

Question 8

A 35-years-old client is going to be started on lisinopril therapy for hypertension.The nurse first performs a test on the client to rule out pregnancy because of which of the following?
1)Lisinopril can cause hypotension in late pregnancy.
2)Lisinopril is pregnancy category C and D.
3)Lisinopril is pregnancy category B.
4)Lisinopril can cause hyperkalemia in pregnant women.

Question 9

Aldosterone antagonist drugs work to lower blood pressure by:
1)Blocking receptors for aldosterone in the adrenal glands.
2)Blocking the AT1 receptors in the RAAS pathway.
3)Blocking the formation of renin in the RAAS pathway.
4)Blocking receptors for aldosterone in the kidneys.

Question 10

The client is starting on lisinopril therapy for hypertension and heart failure.The nurse instructs the client to return for laboratory monitoring because of the risk of:
1)Hyponatremia.
2)Hyperkalemia.
3)Hypokalemia.
4)Hypernatremia.

Question 11

ACE inhibitor drugs prevent ACE from breaking down _______, which results in some of the serious adverse effects of the ACE inhibitors.
1)Bradykinin
2)Renin
3)Aldosterone
4)RAAS

Question 12

The cardiac remodeling changes of the heart caused by angiotensin II increase the risk of:
1)Myocardial infarction and cerebrovascular accident.
2)Hypotension and dehydration.
3)Hypotrophy of myocyte cells.
4)A breakdown of fatty plaque deposits.

Question 13

The angiotensin-converting enzyme converts angiotensin I almost instantly to:
1)Renin.
2)Aldosterone.
3)Angiotensinogen.
4)Angiotensin II.

Question 14

The kidneys response to which occurrence in the body by releasing renin?
1)Lowered blood pressure; dehydration
2)Increased blood pressure; stress, anxiety
3)Increased blood pressure; increased peripheral resistance
4)Lowered blood pressure; decreased cardiac output

Question 15

Additional amounts of aldosterone secretion by the kidneys raises blood pressure due to:
1)Enhanced sodium reabsorption, which increases blood volume.
2)Decreasing sodium absorption, which increases blood volume.
3)Excretion of potassium and hydrogen to retain water.
4)Excretion of sodium and chloride to retain water.

Question 16

ACE inhibitor drugs function in the control of blood pressure:
1)By blocking the conversion of angiotensin II to angiotensinogen.
2)By blocking the conversion of angiotensin I to angiotensin II.
3)By blocking the effects of angiotensin II.
4)By directly inhibiting renin.

Question 17

The arterioles of which organ are most sensitive to the vasopressin action of angiotensin II?
1)The liver
2)The heart
3)The lungs
4)The kidneys

Question 18

Which organ has the primary responsibility in converting angiotensin I to angiotensin II?
1)The liver
2)The kidneys
3)The heart
4)The lungs

Question 19

The nurse is reviewing the diet history of a patient about to start on lisinopril therapy for hypertension.Which part of the client's current dietary intake must be altered while on lisinopril therapy?
1)Use of multiple vitamins
2)Use of calcium supplements
3)Use of potassium supplements
4)Use of fish oil supplements

Question 20

The peptide that is circulating in the blood that can cause profound vasoconstriction is called:
1)Fibrogen.
2)Angiotensin.
3)Kinase.
4)Sodium.