Deck 5: Adverse Drug Reactions

Question 1

Sarah developed a rash after using a topical medication. This is a type __ allergic drug reaction.

A)I
B)II
C)III
D)IV

Answer 1

IV

Question 2

Drugs that are prone to cause adverse drug effects include:

A)Diuretics
B)Inhaled anticholinergics
C)Insulins
D)Stimulants

Answer 2

Insulins

Question 3

The U.S. Food and Drug Administration MedWatch system is activated when:

A)There is an adverse event to a vaccine
B)A patient has a severe reaction that is noted in the "Severe Reaction" section on the medication label
C)A lactating woman takes a medication that is potentially toxic to the breastfeeding infant
D)An adverse event or serious problem that is not already identified on the label occurs

Answer 3

An adverse event or serious problem that is not already identified on the label occurs

Question 4

The type of ADR that is idiosyncratic when a drug is given in the usual therapeutic doses is type:

A)A
B)B
C)C
D)D

Question 5

A first-dose reaction may include:

A)Orthostatic hypotension that does not occur with repeated doses
B)Purple glove syndrome with phenytoin use
C)Hemolytic anemia from ceftriaxone use
D)Contact dermatitis from neomycin use

Question 6

The Vaccine Adverse Events Reporting System is:

A)A mandatory reporting system for all health-care providers for when they encounter an adverse vaccine event
B)A voluntary reporting system that health-care providers or consumers may use to report vaccine adverse events
C)Utilized to send out safety alerts regarding emerging vaccine safety issues
D)Activated when a vaccine has been proven to cause significant adverse effects
E) Adverse Drug Reactions

Question 7

Anaphylactic shock is a:

A)Type I reaction, called immediate hypersensitivity reaction
B)Type II reaction, called cytotoxic hypersensitivity reaction
C)Type III allergic reaction, called immune complex hypersensitivity
D)Type IV allergic reaction, called delayed hypersensitivity reaction

Question 8

Infants and young children are at higher risk of ADRs due to:

A)Immature renal function in school-age children
B)Lack of safety and efficacy studies in the pediatric population
C)Children's skin being thicker than adults, requiring higher dosages of topical medication
D)Infant boys having a higher proportion of muscle mass, leading to a higher volume of distribution

Question 9

Digoxin may cause a type A ADR due to:

A)Idiosyncratic effects
B)Its narrow therapeutic index
C)Being a teratogen
D)Being a carcinogen

Question 10

A 24-year-old male received multiple fractures in a motor vehicle accident that required significant amounts of opioid medication to treat his pain. He is at risk for a _____ ADR when he no longer requires the opioids.

A)Rapid
B)First-dose
C)Late
D)Delayed

Question 11

Malignant hyperthermia after administration of anesthesia is an example of:

A)A hypersensitivity reaction
B)A late-onset reaction
C)A genetic receptor abnormality
D)A drug-drug reaction

Question 12

The elderly are at high risk of ADRs due to:

A)Having greater muscle mass than younger adults, leading to higher volume of distribution
B)The extensive studies that have been conducted on drug safety in this age group
C)The blood-brain barrier being less permeable, requiring higher doses to achieve therapeutic effect
D)Age-related decrease in renal function

Question 13

Medical conditions that can predispose a patient to ADRs include:

A)Chronic kidney disease
B)Asthma
C)Chronic daily headache
D)Pneumonia

Question 14

A patient may develop neutropenia from using topical Silvadene for burns. Neutropenia is a(n):

A)Cytotoxic hypersensitivity reaction
B)Immune complex hypersensitivity
C)Immediate hypersensitivity reaction
D)Delayed hypersensitivity reaction

Question 15

Which of the following patients would be at higher risk of experiencing adverse drug reactions (ADRs):

A)A 32-year-old male
B)A 22-year-old female
C)A 3-month-old female
D)A 48-year-old male