Deck 16: The Microcirculation and Lymphatic System: Capillary Fluid Exchange, Interstitial Fluid, and Lymph Flow

Question 1

An decrease in which of the following tends to increase lymph flow?

A)Interstitial hydrostatic pressure
B)Plasma colloid osmotic pressure
C)Capillary hydrostatic pressure
D)Interstitial colloid osmotic pressure
E)Capillary hydraulic permeability

Answer 1

B

Question 2

A decrease in arteriole diameter would most likely result in which set of changes in a microcirculatory bed?

Answer 2

D

Question 3

A 65-year-old man has a 20-year history of alcoholism and liver disease. He visits his physician complaining of swelling of his extremities. A decrease in which of the following is one of the most likely cause of the ascites?

A)Capillary hydrostatic pressure
B)Arteriole conductance
C)Interstitial hydrostatic pressure
D)Plasma colloid osmotic pressure
E)Interstitial colloid osmotic pressure

Answer 3

D

Question 4

Which one of the following substances in plasma does not contribute to plasma colloid osmotic pressure?

A)Globulins
B)Fibrinogen
C)Albumin
D)NaCl

Question 5

A decrease in which of the following tends to decrease filtration rate across a capillary wall?

A)Plasma colloid osmotic pressure
B)Hydraulic conductivity of the wall
C)Plasma albumin concentration
D)Interstitial hydrostatic pressure
E)Arteriole resistance

Question 6

Listed below are the hydrostatic and oncotic pressures across a muscle capillary wall.
Venous hydrostatic pressure $= 5 \mathrm {~mm} \mathrm { Hg }$
Arterial pressure $= 100 \mathrm {~mm} \mathrm { Hg }$
Capillary hydrostatic pressure $= 35 \mathrm {~mm} \mathrm { Hg }$
Plasma colloid osmotic pressure $= 25 \mathrm {~mm} \mathrm { Hg }$
Interstitial colloid osmotic pressure $= 10 \mathrm {~mm} \mathrm { Hg }$
Interstitial hydrostatic pressure $= - 5 \mathrm {~mm} \mathrm { Hg }$
What is the net filtration pressure (in $\mathrm { mm } \mathrm { Hg }$ ) for fluid movement across the capillary wall?
A. 0
B. 5
C. 10
D. 15
E. 25

Question 7

Use the data below to calculate the rate of net fluid movement (in $\mathrm { mL } / \mathrm { min }$ ) across the capillary wall.
Plasma colloid osmotic pressure $= 40 \mathrm {~mm} \mathrm { Hg }$
Cap illary hydrostatic pressure $= 10 \mathrm {~mm} \mathrm { Hg }$
Venous hydrostatic pressure $= 5 \mathrm {~mm} \mathrm { Hg }$
Arterial pressure $= 80 \mathrm {~mm} \mathrm { Hg }$
Interstitial hydrostatic pressure $= 5 \mathrm {~mm} \mathrm { Hg }$
Interstitial colloid osmotic pressure $= 5 \mathrm {~mm} \mathrm { Hg }$
Filtration coefficient $= 10 \mathrm {~mL} / \mathrm { min } / \mathrm { mm } \mathrm { Hg }$
A. 100 (filtration)
B. 200 (reabsorption)
C. 200 (filtration)
D. 300 (filtration)
E. 300 (reabsorption)

Question 8

Which of the following set of changes would be expected to increase the net movement of sodium across a muscle capillary wall?

Question 9

Use the data below to calculate the filtration coefficient for the capillary bed (in mL/min/mmHg). Plasma colloid osmotic pressure $= 30 \mathrm {~mm} \mathrm { Hg }$
Capillary hydrostatic pressure $= 40 \mathrm {~mm} \mathrm { Hg }$
Interstitial hydrostatic pressure $= 5 \mathrm {~mm} \mathrm { Hg }$
Interstitial colloid osmotic pressure $= 5 \mathrm {~mm} \mathrm { Hg }$
Filtration rate $= 150 \mathrm {~mL} / \mathrm { min }$
Venous hydrostatic pressure $= 10 \mathrm {~mm} \mathrm { Hg }$
A. 10
B. 15
C. 20
D. 25
E. 30

Question 10

A healthy 20 -year-old medical student has an exercise stress test. Which set of changes would be expected to occur in the student's skeletal muscles during exercise?

Question 11

Which of the following is true regarding plasma colloid osmotic pressure?

A)It is less than interstitial colloid osmotic pressure
B)It decreases by 50% in the muscle capillaries as blood flows from the arteriole end to the venous end
C)It is primarily caused by the presence of substances in the plasma such as sodium and potassium
D)It increases in response to an increase in plasma albumin concentration

Question 12

An increase in which of the following would tend to decrease lymph flow?

A)Hydraulic conductivity of the capillary wall
B)Plasma colloid osmotic pressure
C)Capillary hydrostatic pressure
D)Precapillary arteriole diameter
E)Interstitial colloid osmotic pressure

Question 13

A decrease in which of the following tends to increase filtration rate across a capillary wall?

A)Arterial pressure
B)Hydraulic conductivity of the wall
C)Interstitial albumin concentration
D)Capillary hydrostatic pressure
E)Arteriole resistance

Question 14

A decrease in which of the following tends to increase capillary hydrostatic pressure?

A)Arteriole diameter
B)Arteriole resistance
C)Interstitial albumin concentration
D)Capillary filtration coefficient
E)Plasma colloid osmotic pressure

Question 15

A decrease in which of the following would be expected in the skeletal microcirculation in a patient with nephrosis?

A)Capillary filtration rate
B)Plasma colloid osmotic pressure
C)Lymph flow
D)Capillary hydraulic permeability
E)Arteriole resistance