Deck 26: Nutrition Gene Interactions in Health and Disease
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Deck 26: Nutrition Gene Interactions in Health and Disease
1
Genetic traits do not affect a person's perception of sweet and savory tastes.
True
2
Most of the disorders resulting from single-gene defects are rare.
True
3
Increased level of physical activity appears to help people with pro-obesity gene variants lose weight.
True
4
Genes replicate themselves exactly over generations, and lasting modifications in them almost never occur.
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5
The probability of disease development among people with certain genetic traits can sometimes be lowered by lifestyle factors such as diet and exercise.
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6
Sitosterolemia is treated by low-phenylalanine diets.
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7
Genetic traits are the main cause of the recent epidemics of obesity and diabetes.
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8
Individuals with hemochromatosis absorb more calcium than normal.
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9
Some people get the set of genes that make them highly sensitive to bitter-tasting foods.
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10
DNA is placed in the endoplasmic reticulum.
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11
Enzymes and other proteins produced as a result of genetic codes are central to life and health because they determine which chemical changes will take place within the body.
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12
It is estimated that 90% of DNA alterations associated with disease are due to genes rather than gene variants.
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13
Hemochromatosis is a fairly common single-gene defect disorder.
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14
Gene variants related to impaired folate and choline utilization can decrease the need for folate and choline.
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15
All humans share 99.9% of the same DNA.
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16
Women who have certain gene variants have a higher risk of developing breast cancer if they regularly consume cabbages.
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17
Humans have 30 pairs of chromosomes.
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18
Personalized modifications of dietary intake based on genotypes will become standard practice in clinical dietetics and medicine.
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19
Knowledge of an individual's genetic makeup does not provide enough information to reliably indicate disease risk.
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20
All sections of DNA code for protein synthesis.
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21
PKU causes high levels of _____ to build up in the blood.
A) lysine
B) threonine
C) phenylalanine
D) methionine
E) valine
A) lysine
B) threonine
C) phenylalanine
D) methionine
E) valine
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22
Among individuals with particular gene types, high-fat diets increase insulin resistance and fat stores in the liver and increase the risk of _____.
A) galactosemia
B) phenylketonuria
C) type 2 diabetes
D) heart disease and obesity
E) hepatitis B
A) galactosemia
B) phenylketonuria
C) type 2 diabetes
D) heart disease and obesity
E) hepatitis B
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23
People with galactosemia must avoid _____ for life.
A) fruits
B) vegetable oils
C) grains
D) milk and milk products
E) fish
A) fruits
B) vegetable oils
C) grains
D) milk and milk products
E) fish
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24
Which structure in the nuclei of cells contains genes?
A) membrane
B) endoplasmic reticulum
C) chromosomes
D) ribosome
E) cytoplasm
A) membrane
B) endoplasmic reticulum
C) chromosomes
D) ribosome
E) cytoplasm
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25
What percentage of an individual's DNA is unique?
A) 0.1%
B) 0.9%
C) 1%
D) 2%
E) 9%
A) 0.1%
B) 0.9%
C) 1%
D) 2%
E) 9%
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26
Genomics includes the scientific study of complex diseases such as heart disease, diabetes, cancer, and _____.
A) celiac disease
B) osteoporosis
C) anemia
D) asthma
E) scurvy
A) celiac disease
B) osteoporosis
C) anemia
D) asthma
E) scurvy
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27
The human genome is estimated to contain _____ genes.
A) 10,000 to 12,000
B) 13,000 to 15,000
C) 16,000 to 18,000
D) 20,000 to 25,000
E) 26,000 to 30,000
A) 10,000 to 12,000
B) 13,000 to 15,000
C) 16,000 to 18,000
D) 20,000 to 25,000
E) 26,000 to 30,000
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28
All babies born in the United States and many other countries are tested for _____ after birth.
A) PKU
B) galactosemia
C) hemochromatosis
D) sitosterolemia
E) cystic fibrosis
A) PKU
B) galactosemia
C) hemochromatosis
D) sitosterolemia
E) cystic fibrosis
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29
Hemochromatosis is treated with medications and a diet low in _____.
A) sodium and potassium
B) milk and milk products
C) gluten and plant sterols
D) calcium and vitamin D
E) iron and vitamin C
A) sodium and potassium
B) milk and milk products
C) gluten and plant sterols
D) calcium and vitamin D
E) iron and vitamin C
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30
A nucleotide consists of a base plus a molecule of _____ and one of phosphoric acid.
A) sugar
B) water
C) fat
D) nitrate
E) phosphate
A) sugar
B) water
C) fat
D) nitrate
E) phosphate
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31
A nucleotide consists of a base, a molecule of sugar, and _____.
A) hydrochloric acid
B) sulfuric acid
C) nitric acid
D) phosphoric acid
E) citric acid
A) hydrochloric acid
B) sulfuric acid
C) nitric acid
D) phosphoric acid
E) citric acid
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32
How is PKU treated?
A) medication
B) surgery
C) elimination of milk and milk products
D) a low-phenylalanine diet
E) a high-protein diet
A) medication
B) surgery
C) elimination of milk and milk products
D) a low-phenylalanine diet
E) a high-protein diet
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33
_____ refers to a different form of a gene that has a different functional status than the original gene.
A) Chromosome
B) Epigenetic
C) Genome
D) Genotype
E) Gene variant
A) Chromosome
B) Epigenetic
C) Genome
D) Genotype
E) Gene variant
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34
The DNA base pairs are adenine, thymine, guanine, and _____.
A) glutamic acid
B) proline
C) glutamine
D) choline
E) cytosine
A) glutamic acid
B) proline
C) glutamine
D) choline
E) cytosine
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35
A child suffering from galactosemia can eat _____.
A) whey
B) yogurt
C) beef
D) cheese
E) nonfat dry milk
A) whey
B) yogurt
C) beef
D) cheese
E) nonfat dry milk
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36
The influence of gene variants on weight gain is decreased by _____.
A) an increased intake of omega-3 fatty acids
B) physical activity
C) medication
D) low-fat diets
E) low-carbohydrate diets
A) an increased intake of omega-3 fatty acids
B) physical activity
C) medication
D) low-fat diets
E) low-carbohydrate diets
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37
Which substances, produced as a result of genetic codes, are central to life and health because they determine which chemical changes will take place within the body?
A) glucose and hormones
B) enzymes and proteins
C) cholesterol and triglycerides
D) insulin and glucagon
E) glycogen and water
A) glucose and hormones
B) enzymes and proteins
C) cholesterol and triglycerides
D) insulin and glucagon
E) glycogen and water
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38
Noncoding segments of DNA contain _____.
A) genetic codes for protein formation
B) genetic codes for enzyme production
C) instructions for the regulation of gene activity
D) instructions for growth
E) instructions for healing
A) genetic codes for protein formation
B) genetic codes for enzyme production
C) instructions for the regulation of gene activity
D) instructions for growth
E) instructions for healing
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39
How many pairs of chromosomes do humans have?
A) 19
B) 23
C) 27
D) 31
E) 35
A) 19
B) 23
C) 27
D) 31
E) 35
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40
What is the combined term for "genes" and "chromosomes"?
A) genome
B) genes
C) genotype
D) genomics
E) epigenetics
A) genome
B) genes
C) genotype
D) genomics
E) epigenetics
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41
Match between columns
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42
People who prefer sweet and savory tastes tend to have a higher _____ than people who do not.
A) body mass index
B) blood pressure
C) waist circumference
D) heart rate
E) heart rate
A) body mass index
B) blood pressure
C) waist circumference
D) heart rate
E) heart rate
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43
High blood levels of phenylalanine during growth lead to _____.
A) mental retardation
B) hyperactivity
C) poor vision
D) asthma
E) a compromised immune system
A) mental retardation
B) hyperactivity
C) poor vision
D) asthma
E) a compromised immune system
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44
Catherine is a college senior who is taking a health and nutrition course. The class is studying family health history. After completing her family health history project, Catherine realizes that she has a family history of breast cancer and obesity. Catherine wants to continue to study and learn how she can reduce her risk of certain diseases through lifestyle changes.
What should Catherine do to decrease her chances of developing gene-related diseases?
A) Nothing, she can't change her genotype.
B) talk to her doctor about having her genetic profile mapped and then altered accordingly
C) increase her physical activity and vegetable intake and avoid harmful environmental factors
D) talk to a genetic therapist
E) try vitamin and mineral supplements
What should Catherine do to decrease her chances of developing gene-related diseases?
A) Nothing, she can't change her genotype.
B) talk to her doctor about having her genetic profile mapped and then altered accordingly
C) increase her physical activity and vegetable intake and avoid harmful environmental factors
D) talk to a genetic therapist
E) try vitamin and mineral supplements
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45
Catherine is a college senior who is taking a health and nutrition course. The class is studying family health history. After completing her family health history project, Catherine realizes that she has a family history of breast cancer and obesity. Catherine wants to continue to study and learn how she can reduce her risk of certain diseases through lifestyle changes.
How can Catherine modify her diet to lower her risk of developing breast cancer?
A) eliminate caffeine
B) eliminate fried foods
C) increase her folate intake
D) regularly consume cruciferous vegetables
E) regularly consume calcium and vitamin D
How can Catherine modify her diet to lower her risk of developing breast cancer?
A) eliminate caffeine
B) eliminate fried foods
C) increase her folate intake
D) regularly consume cruciferous vegetables
E) regularly consume calcium and vitamin D
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46
Catherine is a college senior who is taking a health and nutrition course. The class is studying family health history. After completing her family health history project, Catherine realizes that she has a family history of breast cancer and obesity. Catherine wants to continue to study and learn how she can reduce her risk of certain diseases through lifestyle changes.
Catherine knows she should eat more vegetables, but she cannot stand their bitter taste. What is most likely the reason that vegetables taste intensely bitter to Catherine?
A) Catherine may have a set of genes that make her nose extremely sensitive to the smell of vegetables.
B) Catherine may have a set of genes that make her highly sensitive to bitter tastes.
C) Catherine's mother never liked vegetables and did not eat many when she was pregnant with Catherine; therefore, Catherine developed a genetically sensitive palate.
D) Catherine simply believes vegetables are bitter tasting, and it is all in her head.
E) Catherine has a single-gene defect.
Catherine knows she should eat more vegetables, but she cannot stand their bitter taste. What is most likely the reason that vegetables taste intensely bitter to Catherine?
A) Catherine may have a set of genes that make her nose extremely sensitive to the smell of vegetables.
B) Catherine may have a set of genes that make her highly sensitive to bitter tastes.
C) Catherine's mother never liked vegetables and did not eat many when she was pregnant with Catherine; therefore, Catherine developed a genetically sensitive palate.
D) Catherine simply believes vegetables are bitter tasting, and it is all in her head.
E) Catherine has a single-gene defect.
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47
Exposure to famine during early pregnancy can promote the development of gene variants that modify glucose utilization in ways that increase the risk of _____.
A) galactosemia
B) celiac disease
C) hypertension
D) hemochromatosis
E) type 2 diabetes
A) galactosemia
B) celiac disease
C) hypertension
D) hemochromatosis
E) type 2 diabetes
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48
DNA is _____.
A) a single helix
B) a double helix
C) a triple helix
D) disc-shaped
E) non-helical
A) a single helix
B) a double helix
C) a triple helix
D) disc-shaped
E) non-helical
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49
How is sitosterolemia treated?
A) elimination of phenylalanine
B) elimination of gluten
C) a diet low in lactose
D) a diet low in plant sterols
E) a diet low in sodium
A) elimination of phenylalanine
B) elimination of gluten
C) a diet low in lactose
D) a diet low in plant sterols
E) a diet low in sodium
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50
Which food most likely contains plant sterols?
A) bacon
B) chicken
C) almonds
D) yogurt
E) cheese
A) bacon
B) chicken
C) almonds
D) yogurt
E) cheese
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51
People born with a high sensitivity to bitter tastes tend to dislike _____.
A) milk
B) canola oil
C) spinach
D) apples
E) tomatoes
A) milk
B) canola oil
C) spinach
D) apples
E) tomatoes
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52
Diseases such as diabetes and cancer are typically caused by interactions between genetic traits and _____.
A) psychological factors
B) smoking
C) dietary habits
D) environmental factors
E) physical inactivity
A) psychological factors
B) smoking
C) dietary habits
D) environmental factors
E) physical inactivity
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53
Individuals with hemochromatosis absorb more _____ than normal.
A) iron
B) zinc
C) vitamin B 12
D) folate
E) calcium
A) iron
B) zinc
C) vitamin B 12
D) folate
E) calcium
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54
Which single-gene defect disorder is fairly common and affects 1 in 300 Caucasians?
A) galactosemia
B) hemochromatosis
C) sitosterolemia
D) muscular dystrophy
E) PKU
A) galactosemia
B) hemochromatosis
C) sitosterolemia
D) muscular dystrophy
E) PKU
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55
Which of the following statements is true of hemochromatosis?
A) It is a condition caused by the inability of the cells in the small intestine to dispose of plant sterols.
B) It causes plaque buildup in arteries and increases the risk of stroke.
C) It is treated with a low-galactose diet and excessive physical activity.
D) It is a single-gene disorder caused by a lack of the enzyme phenylalanine hydroxylase.
E) It worsens when excess vitamin C is ingested.
A) It is a condition caused by the inability of the cells in the small intestine to dispose of plant sterols.
B) It causes plaque buildup in arteries and increases the risk of stroke.
C) It is treated with a low-galactose diet and excessive physical activity.
D) It is a single-gene disorder caused by a lack of the enzyme phenylalanine hydroxylase.
E) It worsens when excess vitamin C is ingested.
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56
Accumulation of plant sterols in the body increases the risk of _____.
A) obesity
B) heart disease
C) diabetes
D) cancer
E) celiac disease
A) obesity
B) heart disease
C) diabetes
D) cancer
E) celiac disease
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