Deck 15: Epidemiology of Oral Cavity Cancer

Question 1

Malignancies of the oral cavity and lip caused approximately 177,384 deaths in 2018 (119,693 in men and 57,691 in women).

Answer 1

True

Question 2

Major risk factors for oral cavity cancer include tobacco, alcohol, and certain strains of human papilloma virus.

Answer 2

True

Question 3

More than 60% of deaths from oral cavity cancer occur in developed countries.

Answer 3

False

Question 4

Alcohol abuse and tobacco addiction synergistically increase the risk of developing oral cavity cancer.

Question 5

HPV-16 exposure heightens the risk of oral cavity cancer in young women but not in young men.

Question 6

Compared to no exposure, chronic exposure to alcohol and tobacco increases the risk of oral cavity cancer by:

A) 2-fold.
B) 4-fold.
C) 10-fold.
D) 35-fold.

Question 7

What strain of human papilloma virus (HPV) has been etiologically linked to the development of oral cavity cancer?

A) HPV 16
B) HPV 18
C) HPV 35
D) a and b are correct.

Question 8

The Plummer Vinson Syndrome includes all of the following symptoms except:

A) iron deficiency anemia.
B) dysphagia.
C) atrophy of the oral cavity mucosa.
D) melanin pigmentation of the oral cavity mucosa.

Question 9

Which of the following factors markedly increases the risk of developing squamous cell carcinoma of the hard palate?

A) Chewing betel quid
B) Reverse smoking
C) Chronic cigarette smoking
D) Chronic alcohol abuse

Question 10

Which of the following is not a major risk factor for the development of lip cancer?

A) Pipe smoking
B) Cigar smoking
C) Chronic exposure to UV radiation
D) Alcohol abuse

Question 11

Describe the global burden of oral cavity cancer.

Question 12

Discuss the epidemiologic evidence supporting synergism between tobacco and alcohol in promoting the development of oral cavity cancer.

Question 13

Discuss the epidemiologic evidence supporting HPV-16 as a major risk factor for oral cavity cancer.

Question 14

Discuss nutritional deficits that increase the risk of developing oral cavity cancer.

Question 15

Define the terms leukoplakia and erythroplakia and briefly discuss causes of these premalignant conditions.