Deck 9: Psychological Disorders

Question 1

A drug that produces a schizophrenia-like state is ______.

A) imipramine
B) barbituric acid
C) ketamine
D) chlorpromazine

Answer 1

C

Question 2

Blockade of postsynaptic dopamine receptors would be predicted to cause which of the following clinical effects?

A) movement disorders
B) blurred vision
C) tremors
D) hypotension

Answer 2

A

Question 3

The dopamine theory of schizophrenia is supported by which of the following statements?

A) Someone with schizophrenia may have reduced synthesis of dopamine.
B) Drugs that relieve the positive symptoms of schizophrenia are dopamine antagonists.
C) Cocaine is effective as an antipsychotic.
D) The effects of antipsychotics are not seen for several weeks after treatment.

Answer 3

B

Question 4

Which of the following is TRUE of negative schizophrenia symptoms?

A) Chlorpromazine is effective in treating negative symptoms.
B) Negative symptoms relate to an overactive glutamate system.
C) Paranoia is an example of a negative symptom.
D) Negative symptoms involve the loss feelings.

Question 5

The first phase of schizophrenia is referred to as the ______.

A) prophylactic phase
B) prodromal phase
C) primal phase
D) principal phase

Question 6

Which of the following drugs are most likely to be prescribed for a person with schizophrenia?

A) mescaline
B) atropine
C) nicotine
D) clozapine

Question 7

Which of the following applies to tricyclic antidepressants?

A) They cause release of monoamines.
B) They enhance synthesis of monoamines.
C) They inhibit reuptake of monoamines.
D) They inactivate the enzyme monoamine oxidase.

Question 8

Which of the following is NOT a drug action that appears to be involved in the
Antidepressant actions of drugs?

A) blockade of noradrenaline reuptake
B) blockade of serotonin reuptake
C) inhibition of monoamine oxidase
D) stimulation of GABA receptors

Question 9

All of the following are considered symptoms of major depression except ______.

A) hedonia
B) biased thinking
C) altered appetite
D) fatigue

Question 10

The effect of excess secretion of cortisol on the brain is to ______.

A) increase neuron outgrowth
B) reduce levels of BDNF
C) increase levels of BDNF
D) increase neurogenesis in the hippocampus

Question 11

Which of the following pieces of evidence supports the neurogenic theory of depression?

A) Levels of BDNF in hippocampus of mice decrease after antidepressants.
B) Depression is associated with reduced ventricle volume.
C) Injection of BDNF into the hippocampus has an antidepressant effect.
D) Blocking neurogenesis in mice has an antidepressant effect.

Question 12

Benzodiazepines affect GABA transmission by ______.

A) decreasing the affinity of GABA for the GABA-A receptor
B) increasing the frequency of GABA-A Cl^- channel opening
C) increasing the availability of GABA
D) increasing the duration of GABA-A Cl^- channel opening

Question 13

Which if the following is associated with anxiety?

A) reduced amygdala response to fearful stimuli
B) increased hippocampal response to fearful stimuli
C) increased activation of the insular cortex when attending to internal sensations
D) reduced frontal lobe response when attending to internal sensations

Question 14

A person that experiences a fear of having a panic attack in a social situation is experiencing ______.

A) mania
B) agoraphobia
C) generalized anxiety disorder
D) PTSD

Question 15

Which of the following drugs are most like to be prescribed for a person with anxiety?

A) Haloperidol
B) Chlorpromazine
C) Pentobarbital
D) Prozac

Question 16

What are advantages and disadvantages associated with classification systems for psychological disorders?

Question 17

Discuss the suggestion that understanding the mechanism of action of drugs at the neuronal level has contributed to our understanding of the causes of psychological disorders.

Question 18

Based on your knowledge of the biological basis of psychological disorders, suggest a new type of drug that, if developed, would be more effective in treating either schizophrenia or depression or anxiety.

Question 19

What role does the environment play in the development of psychological disorders?

Question 20

Compared with traditional antipsychotic drugs what are the benefits of using new generation antipsychotics to treat schizophrenia? How do these advantages relate to the mechanism of action of new generation drugs?